Distinct roles of Ape1 protein in the repair of DNA damage induced by ionizing radiation or bleomycin.
about
DNA double-strand-break complexity levels and their possible contributions to the probability for error-prone processing and repair pathway choiceStructure of human apurinic/apyrimidinic endonuclease 1 with the essential Mg2+cofactorProcessing of damaged DNA ends for double-strand break repair in mammalian cellsRequirements for 5'dRP/AP lyase activity in Ku.A stochastic model of DNA fragments rejoiningDistinct roles of Ape1 protein, an enzyme involved in DNA repair, in high or low linear energy transfer ionizing radiation-induced cell killing.Post-irradiation chemical processing of DNA damage generates double-strand breaks in cells already engaged in repair.Removal of reactive oxygen species-induced 3'-blocked ends by XPF-ERCC1.Inhibitors of the apurinic/apyrimidinic endonuclease 1 (APE1)/nucleophosmin (NPM1) interaction that display anti-tumor propertiesFractionated Radiation Exposure of Rat Spinal Cords Leads to Latent Neuro-Inflammation in Brain, Cognitive Deficits, and Alterations in Apurinic Endonuclease 1.DNA double-strand break repair is impaired in presenescent Syrian hamster fibroblastsBase excision repair: contribution to tumorigenesis and target in anticancer treatment paradigmsAPE1-mediated DNA damage repair provides survival advantage for esophageal adenocarcinoma cells in response to acidic bile salts.A threshold of endogenous stress is required to engage cellular response to protect against mutagenesis.Functional analysis of the involvement of apurinic/apyrimidinic endonuclease 1 in the resistance to melphalan in multiple myeloma.Human apurinic/apyrimidinic endonuclease 1.Tracking the processing of damaged DNA double-strand break ends by ligation-mediated PCR: increased persistence of 3'-phosphoglycolate termini in SCAN1 cells.Aberrant expression of redox protein Ape1 in colon cancer stem cells.Elevated level of acetylation of APE1 in tumor cells modulates DNA damage repair.Translesion DNA synthesis in the context of cancer research.Small-molecule inhibitors of DNA damage-repair pathways: an approach to overcome tumor resistance to alkylating anticancer drugs.Myeloprotection by cytidine deaminase gene transfer in antileukemic therapy.A review on protein-protein interaction network of APE1/Ref-1 and its associated biological functions.Structure-based virtual screening toward the discovery of novel inhibitors of the DNA repair activity of the human apurinic/apyrimidinic endonuclease 1.Nanoparticle mediated silencing of DNA repair sensitizes pediatric brain tumor cells to γ-irradiation.The contribution of thermally labile sugar lesions to DNA double-strand break formation in cells grown in the presence of BrdU.Impact of apurinic/apyrimidinic endonuclease 1/redox factor-1 on treatment response and survival in oral squamous cell carcinoma.Functional regulation of the apurinic/apyrimidinic endonuclease 1 by nucleophosmin: impact on tumor biology.Reduced contribution of thermally labile sugar lesions to DNA double strand break formation after exposure to heavy ions.Receptor-based virtual screening and biological characterization of human apurinic/apyrimidinic endonuclease (Ape1) inhibitors.Design and synthesis of 3-carbamoylbenzoic acid derivatives as inhibitors of human apurinic/apyrimidinic endonuclease 1 (APE1).Developing an in silico model of the modulation of base excision repair using methoxyamine for more targeted cancer therapeutics.Apurinic/apyrimidinic endonuclease 1, the sensitive marker for DNA deterioration in dextran sulfate sodium-induced acute colitis.Nanoparticle-mediated knockdown of DNA repair sensitizes cells to radiotherapy and extends survival in a genetic mouse model of glioblastoma.
P2860
Q27014837-3D7E4822-9C49-4AF2-9154-EEF8BD78A473Q27680779-85592AC1-C295-4670-8896-59444EBCABE8Q28000148-D549CBB8-9EA5-48FD-9220-CE94DD28D67DQ34248869-F5427BD0-F324-493C-AD72-16AF99E47EA9Q34427007-6D4763F6-938D-4E42-B0F0-E2C4D38CDBB4Q34431051-4B532D45-7A46-4766-BEE5-AF1870EA308AQ35447479-5B035DAB-4E20-481C-BDAB-F9C427C4CBCAQ35566661-A57DB5DE-7CCD-4712-83FC-A22E6E41E720Q35599868-3E194379-B84A-4C63-AA63-795830EB5192Q35712315-E31C30B5-3770-4241-873A-34871720CF2AQ35803657-A580902A-3793-4195-9B77-B6335C740A08Q35955906-74A1E877-8D92-4F99-98CA-A89BEA5D952AQ37086100-428BF40C-BCA2-470C-ACF5-24615110A104Q37089340-25A8B952-24A9-479C-B0A2-41E39C082BACQ37509136-B08C7CBD-EA7A-4526-8955-86C517BA29F2Q37512952-27A13E48-C308-44A9-95C4-5A73D714B05FQ37631883-4777FA06-BF36-4A71-9528-4644F6BA6BCDQ37652446-7111B0FA-8A23-4EF1-BF24-8AD408ED4534Q37688921-EBD76306-E8F3-4C14-A2DE-8D61DCE9954CQ37952001-0E27723C-4B6D-431A-A2CF-69F8D6DE442EQ38019607-9F2F1255-82CD-4FF1-A3D3-931513A603DBQ38088242-02382748-EB19-4FD3-9D62-019855DF106CQ38383985-854986A1-2A90-4B7A-B1AB-213D84222360Q38733657-4BEAEFFD-71D6-4957-8C63-7C292423E14EQ38909841-A9ED5FE3-80BA-45BF-8C13-7BE84F0492DFQ38928463-D7718A79-A5AA-4EA6-BF7D-70E74901BDA8Q38931527-80A32369-8842-4BE2-BB46-C8D0D005B443Q39129437-DD2A9597-5F0F-403F-A267-964224AAA675Q39172661-E3879F64-E5BD-41E2-A6C6-79532345C72AQ39251743-64649E92-F947-47BB-A4AB-F95F09EF0A99Q39284845-8155889E-280E-46F0-9277-88900944A14AQ41858731-C382FA9D-B570-402E-9E88-0729E99EC24AQ44431067-63FB0F8E-E5D8-4737-850F-B9E68D5FA9D6Q48018806-806516C0-264E-4ED2-B7C3-7221C85667BE
P2860
Distinct roles of Ape1 protein in the repair of DNA damage induced by ionizing radiation or bleomycin.
description
2010 nî lūn-bûn
@nan
2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Distinct roles of Ape1 protein ...... nizing radiation or bleomycin.
@ast
Distinct roles of Ape1 protein ...... nizing radiation or bleomycin.
@en
Distinct roles of Ape1 protein ...... nizing radiation or bleomycin.
@nl
type
label
Distinct roles of Ape1 protein ...... nizing radiation or bleomycin.
@ast
Distinct roles of Ape1 protein ...... nizing radiation or bleomycin.
@en
Distinct roles of Ape1 protein ...... nizing radiation or bleomycin.
@nl
prefLabel
Distinct roles of Ape1 protein ...... nizing radiation or bleomycin.
@ast
Distinct roles of Ape1 protein ...... nizing radiation or bleomycin.
@en
Distinct roles of Ape1 protein ...... nizing radiation or bleomycin.
@nl
P2860
P356
P1476
Distinct roles of Ape1 protein ...... nizing radiation or bleomycin.
@en
P2093
Bruce Demple
P2860
P304
P356
10.1074/JBC.M110.146498
P407
P577
2010-11-15T00:00:00Z