Granzyme K cleaves the nucleosome assembly protein SET to induce single-stranded DNA nicks of target cells. - Wikidata - wikimedia - TriplyDB

Granzyme K cleaves the nucleosome assembly protein SET to induce single-stranded DNA nicks of target cells.

Granzyme K cleaves the nucleosome assembly protein SET to induce single-stranded DNA nicks of target cells.

http://www.wikidata.org/entity/Q34569924

about

A quarter century of granzymes Structural and functional analysis of novel human cytochrome C targets in apoptosis Granzyme K activates protease-activated receptor-1 Cleavage of survivin by Granzyme M triggers degradation of the survivin-X-linked inhibitor of apoptosis protein (XIAP) complex to free caspase activity leading to cytolysis of target tumor cells Delivery and therapeutic potential of human granzyme B.Death by a thousand cuts: granzyme pathways of programmed cell death MAIT cells are licensed through granzyme exchange to kill bacterially sensitized targets.Chemotherapeutic-induced apoptosis: a phenotype for pharmacogenomics studies.FADD cleavage by NK cell granzyme M enhances its self-association to facilitate procaspase-8 recruitment for auto-processing leading to caspase cascade Granzyme K inhibits replication of influenza virus through cleaving the nuclear transport complex importin α1/β dimer of infected host cells.Human NK cell lytic granules and regulation of their exocytosis Mechanisms of granule-dependent killing.Distinct profiles of cytotoxic granules in memory CD8 T cells correlate with function, differentiation stage, and antigen exposure Phenotype of NK Cells Determined on the Basis of Selected Immunological Parameters in Children Treated due to Acute Lymphoblastic Leukemia.Expression of multiple granzymes by cytotoxic T lymphocyte implies that they activate diverse apoptotic pathways in target cells.Granzyme K synergistically potentiates LPS-induced cytokine responses in human monocytes.Orphan granzymes find a home.Non-cytotoxic antiviral activities of granzymes in the context of the immune antiviral state.Cell death-independent functions of granzymes: hit viruses where it hurts.Controversies in granzyme biology.Modulation of IL-2Rα with daclizumab for treatment of multiple sclerosis.Blessing or curse? Proteomics in granzyme research.Reprogramming the oncogenic response: SET protein as a potential therapeutic target in cancer.Extracellular granzyme K mediates endothelial activation through the cleavage of protease-activated receptor-1.Granzyme K-deficient mice show no evidence of impaired antiviral immunity.Expression of granzyme B sensitizes ALK+ ALCL tumour cells to apoptosis-inducing drugs.Granzymes A and K differentially potentiate LPS-induced cytokine response.All human granzymes target hnRNP K that is essential for tumor cell viability.Accumulation of the SET protein in HEK293T cells and mild oxidative stress: cell survival or death signaling.Mouse granzyme K has pro-inflammatory potential.Granzyme K displays highly restricted substrate specificity that only partially overlaps with granzyme A.

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P2860

Granzyme K cleaves the nucleosome assembly protein SET to induce single-stranded DNA nicks of target cells.

http://www.wikidata.org/entity/Q34569924

description

2006 nî lūn-bûn

@nan

2006 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2006 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

2006年の論文

@ja

2006年論文

@yue

2006年論文

@zh-hant

2006年論文

@zh-hk

2006年論文

@zh-mo

2006年論文

@zh-tw

2006年论文

@wuu

name

Granzyme K cleaves the nucleos ...... ded DNA nicks of target cells.

@ast

Granzyme K cleaves the nucleos ...... ded DNA nicks of target cells.

@en

Granzyme K cleaves the nucleos ...... ded DNA nicks of target cells.

@nl

type

label

Granzyme K cleaves the nucleos ...... ded DNA nicks of target cells.

@ast

Granzyme K cleaves the nucleos ...... ded DNA nicks of target cells.

@en

Granzyme K cleaves the nucleos ...... ded DNA nicks of target cells.

@nl

prefLabel

Granzyme K cleaves the nucleos ...... ded DNA nicks of target cells.

@ast

Granzyme K cleaves the nucleos ...... ded DNA nicks of target cells.

@en

Granzyme K cleaves the nucleos ...... ded DNA nicks of target cells.

@nl

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P1433

Cell Death & Differentiation

P1476

Granzyme K cleaves the nucleos ...... ded DNA nicks of target cells.

@en

P2093

Fan Z

http://www.w3.org/2001/XMLSchema#string

Guo Y

http://www.w3.org/2001/XMLSchema#string

Hou Q

http://www.w3.org/2001/XMLSchema#string

Hua G

http://www.w3.org/2001/XMLSchema#string

Liu H

http://www.w3.org/2001/XMLSchema#string

Lu H

http://www.w3.org/2001/XMLSchema#string

Zhang H

http://www.w3.org/2001/XMLSchema#string

Zhang Q

http://www.w3.org/2001/XMLSchema#string

Zhao T

http://www.w3.org/2001/XMLSchema#string

P2860

Granzyme A activates an endoplasmic reticulum-associated caspase-independent nuclease to induce single-stranded DNA nicks

HMG2 interacts with the nucleosome assembly protein SET and is a target of the cytotoxic T-lymphocyte protease granzyme A

DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis

Cleaving the oxidative repair protein Ape1 enhances cell death mediated by granzyme A

Can, a putative oncogene associated with myeloid leukemogenesis, may be activated by fusion of its 3' half to different genes: characterization of the set gene

Recombinant human granzyme A binds to two putative HLA-associated proteins and cleaves one of them

Purification of three cytotoxic lymphocyte granule serine proteases that induce apoptosis through distinct substrate and target cell interactions

The 2.2-A crystal structure of human pro-granzyme K reveals a rigid zymogen with unusual features

Tumor suppressor NM23-H1 is a granzyme A-activated DNase during CTL-mediated apoptosis, and the nucleosome assembly protein SET is its inhibitor

Granzyme M mediates a novel form of perforin-dependent cell death

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489-499

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scholarly article

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10.1038/SJ.CDD.4402040

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3

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14

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P577

2006-09-29T00:00:00Z

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6785695

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1042677375

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17008916

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