Extensive nuclear localization of alpha-synuclein in normal rat brain neurons revealed by a novel monoclonal antibody.
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The synaptic pathology of alpha-synuclein aggregation in dementia with Lewy bodies, Parkinson's disease and Parkinson's disease dementiaUnfolded Protein Response and Macroautophagy in Alzheimer's, Parkinson's and Prion DiseasesNeuronal response in Alzheimer's and Parkinson's disease: the effect of toxic proteins on intracellular pathwaysThe Synaptic Function of α-SynucleinC-Terminal Tyrosine Residue Modifications Modulate the Protective Phosphorylation of Serine 129 of α-Synuclein in a Yeast Model of Parkinson's Disease.Alpha-synuclein structure, functions, and interactionsSelective binding of nuclear alpha-synuclein to the PGC1alpha promoter under conditions of oxidative stress may contribute to losses in mitochondrial function: implications for Parkinson's diseaseDynamic transport and localization of alpha-synuclein in primary hippocampal neurons.Nitrated alpha-synuclein induces the loss of dopaminergic neurons in the substantia nigra of rats.Novel AAV-based rat model of forebrain synucleinopathy shows extensive pathologies and progressive loss of cholinergic interneuronsThe novel Parkinson's disease linked mutation G51D attenuates in vitro aggregation and membrane binding of α-synuclein, and enhances its secretion and nuclear localization in cells.Biochemical and morphological consequences of human α-synuclein expression in a mouse α-synuclein null background.Alpha-synuclein function and dysfunction on cellular membranes.Icariin reduces α-synuclein over-expression by promoting α-synuclein degradation.Altered machinery of protein synthesis is region- and stage-dependent and is associated with α-synuclein oligomers in Parkinson's disease.Post-translational modifications of α-synuclein contribute to neurodegeneration in the colon of elderly individuals.Neuronal hemoglobin in mitochondria is reduced by forming a complex with α-synuclein in aging monkey brains.Age- and brain region-dependent α-synuclein oligomerization is attributed to alterations in intrinsic enzymes regulating α-synuclein phosphorylation in aging monkey brains.Alpha-synuclein-immunopositive myenteric neurons and vagal preganglionic terminals: autonomic pathway implicated in Parkinson's disease?Direct detection of alpha synuclein oligomers in vivoMacrophages are unsuccessful in clearing aggregated alpha-synuclein from the gastrointestinal tract of healthy aged Fischer 344 rats.DNA methylation, a hand behind neurodegenerative diseases.Alpha-synuclein immunopositive aggregates in the myenteric plexus of the aging Fischer 344 rat.Anti-apoptotic effect of Shudipingchan granule in the substantia nigra of rat models of Parkinson's disease.Principles of self-organization in biological pathways: a hypothesis on the autogenous association of alpha-synucleinα-Synuclein in Parkinson's disease.Aberrant autophagy and parkinsonism: does correction rescue from disease progression?α-Synuclein promotes clathrin-mediated NMDA receptor endocytosis and attenuates NMDA-induced dopaminergic cell death.An antibody with high reactivity for disease-associated α-synuclein reveals extensive brain pathology.Mechanisms of alpha-synuclein action on neurotransmission: cell-autonomous and non-cell autonomous roleRole of Apolipoproteins and α-Synuclein in Parkinson's Disease.Implication of Alpha-Synuclein Phosphorylation at S129 in Synucleinopathies: What Have We Learned in the Last Decade?Investigational α-synuclein aggregation inhibitors: hope for Parkinson's disease.Cell Biology and Pathophysiology of α-Synuclein.A prolyl oligopeptidase inhibitor, KYP-2047, reduces α-synuclein protein levels and aggregates in cellular and animal models of Parkinson's disease.C-terminal part of α-synuclein mediates its activity in promoting proliferation of dopaminergic cells.Determining nuclear localization of alpha-synuclein in mouse brains.Excess α-synuclein compromises phagocytosis in iPSC-derived macrophagesPink1 interacts with α-synuclein and abrogates α-synuclein-induced neurotoxicity by activating autophagy.In vivo RNAi-mediated alpha-synuclein silencing induces nigrostriatal degeneration
P2860
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P2860
Extensive nuclear localization of alpha-synuclein in normal rat brain neurons revealed by a novel monoclonal antibody.
description
2007 nî lūn-bûn
@nan
2007 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
name
Extensive nuclear localization ...... y a novel monoclonal antibody.
@ast
Extensive nuclear localization ...... y a novel monoclonal antibody.
@en
Extensive nuclear localization ...... y a novel monoclonal antibody.
@nl
type
label
Extensive nuclear localization ...... y a novel monoclonal antibody.
@ast
Extensive nuclear localization ...... y a novel monoclonal antibody.
@en
Extensive nuclear localization ...... y a novel monoclonal antibody.
@nl
prefLabel
Extensive nuclear localization ...... y a novel monoclonal antibody.
@ast
Extensive nuclear localization ...... y a novel monoclonal antibody.
@en
Extensive nuclear localization ...... y a novel monoclonal antibody.
@nl
P2093
P1433
P1476
Extensive nuclear localization ...... y a novel monoclonal antibody.
@en
P2093
P304
P356
10.1016/J.NEUROSCIENCE.2006.12.028
P407
P577
2007-02-01T00:00:00Z