Applications of linking PBPK and PD models to predict the impact of genotypic variability, formulation differences, differences in target binding capacity and target site drug concentrations on drug responses and variability
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Recent Advances in Development and Application of Physiologically-Based Pharmacokinetic (PBPK) Models: a Transition from Academic Curiosity to Regulatory AcceptanceQuantitative Systems Pharmacology: A Framework for Context.A Tutorial on Pharmacodynamic Scripting Facility in Simcyp.Alzheimer disease research in the 21st century: past and current failures, new perspectives and funding prioritiesApplication of a systems pharmacology model for translational prediction of hERG-mediated QTc prolongation.Applications of physiologically based pharmacokinetic modeling for the optimization of anti-infective therapies.Physiologically-based pharmacokinetic models: approaches for enabling personalized medicine.Next generation testing strategy for assessment of genomic damage: A conceptual framework and considerations.Pediatric Development of Bosentan Facilitated by Modeling and Simulation.Development of a Physiologically Based Pharmacokinetic/Pharmacodynamic Model to Predict the Impact of Genetic Polymorphisms on the Pharmacokinetics and Pharmacodynamics Represented by Receptor/Transporter Occupancy of Central Nervous System Drugs.Editorial: The emerging discipline of quantitative systems pharmacology.Physiologically Based Pharmacokinetic Modeling to Evaluate the Systemic Exposure of Gefitinib in CYP2D6 Ultrarapid Metabolizers and Extensive Metabolizers.Bridging the Data Gap From Toxicity Testing to Chemical Safety Assessment Through Computational Modeling
P2860
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P2860
Applications of linking PBPK and PD models to predict the impact of genotypic variability, formulation differences, differences in target binding capacity and target site drug concentrations on drug responses and variability
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2014 nî lūn-bûn
@nan
2014 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի նոյեմբերին հրատարակված գիտական հոդված
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2014年の論文
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2014年学术文章
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2014年学术文章
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2014年学术文章
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2014年学术文章
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2014年学术文章
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2014年學術文章
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name
Applications of linking PBPK a ...... drug responses and variability
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Applications of linking PBPK a ...... drug responses and variability
@en
Applications of linking PBPK a ...... drug responses and variability
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type
label
Applications of linking PBPK a ...... drug responses and variability
@ast
Applications of linking PBPK a ...... drug responses and variability
@en
Applications of linking PBPK a ...... drug responses and variability
@nl
prefLabel
Applications of linking PBPK a ...... drug responses and variability
@ast
Applications of linking PBPK a ...... drug responses and variability
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Applications of linking PBPK a ...... drug responses and variability
@nl
P2093
P2860
P356
P1476
Applications of linking PBPK a ...... drug responses and variability
@en
P2093
Khaled Abduljalil
Manoranjenni Chetty
Masoud Jamei
Nikunjkumar Patel
Rachel H Rose
Theresa Cain
P2860
P356
10.3389/FPHAR.2014.00258
P577
2014-11-26T00:00:00Z