Stat3 inhibitor Stattic exhibits potent antitumor activity and induces chemo- and radio-sensitivity in nasopharyngeal carcinoma - Wikidata - wikimedia - TriplyDB

Stat3 inhibitor Stattic exhibits potent antitumor activity and induces chemo- and radio-sensitivity in nasopharyngeal carcinoma

Stat3 inhibitor Stattic exhibits potent antitumor activity and induces chemo- and radio-sensitivity in nasopharyngeal carcinoma

http://www.wikidata.org/entity/Q34575479

about

Mitochondrial Stat3, the Need for Design Thinking STAT3: A Novel Molecular Mediator of Resistance to Chemoradiotherapy Novel multiplexed assay for identifying SH2 domain antagonists of STAT family proteins Molecular targets for anticancer redox chemotherapy and cisplatin-induced ototoxicity: the role of curcumin on pSTAT3 and Nrf-2 signalling.Stat3 regulates centrosome clustering in cancer cells via Stathmin/PLK1.Extracellular signal-regulated kinase signaling-mediated induction and interaction of FOXO3a and p53 contribute to the inhibition of nasopharyngeal carcinoma cell growth by curcumin WP1066 sensitizes oral squamous cell carcinoma cells to cisplatin by targeting STAT3/miR-21 axis Combined STAT3 and BCR-ABL1 inhibition induces synthetic lethality in therapy-resistant chronic myeloid leukemia βA3/A1-crystallin is a critical mediator of STAT3 signaling in optic nerve astrocytes.Differential roles of STAT3 in the initiation and growth of lung cancer G-CSF Promotes Neuroblastoma Tumorigenicity and Metastasis via STAT3-Dependent Cancer Stem Cell Activation.Ibuprofen and Diclofenac Restrict Migration and Proliferation of Human Glioma Cells by Distinct Molecular Mechanisms.βA3/A1-crystallin and persistent fetal vasculature (PFV) disease of the eye.MiR-23a sensitizes nasopharyngeal carcinoma to irradiation by targeting IL-8/Stat3 pathway.A novel small molecule STAT3 inhibitor, LY5, inhibits cell viability, colony formation, and migration of colon and liver cancer cells.JAK/STAT regulation of Aspergillus fumigatus corneal infections and IL-6/23-stimulated neutrophil, IL-17, elastase, and MMP9 activity.Small-molecule inhibition of STAT3 in radioresistant head and neck squamous cell carcinoma Honokiol as a Radiosensitizing Agent for Colorectal cancers.Stat3 contributes to cancer progression by regulating Jab1/Csn5 expression.Activation of HERV-K Env protein is essential for tumorigenesis and metastasis of breast cancer cells STAT3-Mediated Metabolic Reprograming in Cellular Transformation and Implications for Drug Resistance STAT3-Interacting Proteins as Modulators of Transcription Factor Function: Implications to Targeted Cancer Therapy.Zoledronic acid reverses cisplatin resistance in nasopharyngeal carcinoma cells by activating the mitochondrial apoptotic pathway Suppression of the Growth and Invasion of Human Head and Neck Squamous Cell Carcinomas via Regulating STAT3 Signaling and the miR-21/β-catenin Axis with HJC0152.Combined Treatment with Stattic and Docetaxel Alters the Bax/Bcl-2 Gene Expression Ratio in Human Prostate Cancer Cells STAT3 inhibitor stattic enhances radiosensitivity in esophageal squamous cell carcinoma.The preliminary study of 18F-FLT micro-PET/CT in predicting radiosensitivity of human nasopharyngeal carcinoma xenografts.STAT3 inhibitor NSC74859 radiosensitizes esophageal cancer via the downregulation of HIF-1α.Niclosamide enhances the antitumor effects of radiation by inhibiting the hypoxia-inducible factor-1α/vascular endothelial growth factor signaling pathway in human lung cancer cells.Epigenetic regulation of the extrinsic oncosuppressor PTX3 gene in inflammation and cancer.Valproic acid, an inhibitor of class I histone deacetylases, reverses acquired Erlotinib-resistance of lung adenocarcinoma cells: a Connectivity Mapping analysis and an experimental study.Stattic Enhances Radiosensitivity and Reduces Radio-Induced Migration and Invasion in HCC Cell Lines through an Apoptosis Pathway.Correlation of the expressions of IGF1R-RACK1-STAT3 and Bcl-xl in nasopharyngeal carcinoma with the clinicopathological features and prognosis of nasopharyngeal carcinoma.Impact of STAT3 phosphorylation in glioblastoma stem cells radiosensitization and patient outcome.Targeting the IL-6/JAK/STAT3 signalling axis in cancer.Interaction of stattic, a STAT3 inhibitor with human serum albumin: spectroscopic and computational study.STAT3-Mediated Transcriptional Regulation of Osteopontin in STAT3 Loss-of-Function Related Hyper IgE Syndrome.Caffeic Acid Phenethyl Ester Induces N-myc Downstream Regulated Gene 1 to Inhibit Cell Proliferation and Invasion of Human Nasopharyngeal Cancer Cells.Immune Checkpoint Inhibition in Head and Neck Cancer

P2860

Q26750616-9CC9C8D8-C44C-40C7-B18C-BA71ECB34FD9 Q27003190-70CF60C7-B23B-43B6-B18B-6CDB0C0C650C Q28535402-A8B73083-C51F-4413-AD6F-B763D1104CBB Q30369661-4B69FA9A-0810-41A8-A032-276FFBB0F8B6 Q33654342-AD31A200-B3A0-43BE-A691-5C9ABE461E2D Q33836475-77CB2778-A0C2-4323-9620-43F887F4308E Q34719683-34ADD38E-8B61-4812-9608-1C149DDB3C31 Q35102414-DEF35B85-43BC-4824-8114-A055C916E09C Q35144228-35032C95-FAB9-4F15-997F-45F8561FBBDF Q35288058-F3944C28-9E42-4C2E-9FB8-B52773BD74E1 Q35752008-284017D9-3993-46A4-B971-520C33986523 Q35814510-15000A97-00E0-45C1-BEE2-052A8A7D37B7 Q36338837-7497ACC6-461B-4A0E-B053-F9209C3F9FCF Q36414053-99FC6A9C-56E4-4D2A-8FDE-DAD9E3705026 Q37022338-40150030-FC93-40A4-B92A-9BB8D249A664 Q37098061-FB7F1C5F-AE35-4E90-9056-30877534D3C1 Q37295655-275ED8CC-4002-49E7-941B-EF6115338C2F Q37351849-A7E1F5B8-35F2-4634-B355-36F7B0F48B5C Q37643955-08711DAC-1A47-46AE-97FD-85148B9F0841 Q37708924-111BA310-5604-4224-996A-99B9E007F910 Q38536624-8BAA0E86-C646-4BBB-B64C-023CA887C0AD Q38667977-1409A9BC-099A-4786-8BE9-5717A7684C84 Q38705637-118B6C6F-E0CB-4E68-9092-33E385BCC54C Q38718723-061C899B-E071-434C-BE85-73BADB796D54 Q38723854-81278904-89DA-4DE1-860C-A194C0828011 Q38930318-F48E817B-BE42-444C-9165-52E37BECE7D6 Q38957000-49209C40-C001-42D6-B7C6-CFBE2170B178 Q38979390-E5473C5B-CDD2-4EDF-80FC-B18CB4F30196 Q40104743-D0DC05C9-9D00-4776-B517-C398D9384637 Q41252240-3D24379E-CB04-4524-B266-BDCAEDDBF9D0 Q41837321-23E6E2CB-DB11-46A3-8F28-966CD0AFB601 Q47096604-2513E7DD-0384-4905-B73E-EF549A5B40FC Q48224087-D93E13C1-3B43-4C12-A1FA-8D92608D508F Q49273540-3EF6E62F-A1B4-4C9B-9734-34B6BC232CD3 Q50191433-BE76AFC6-0914-4151-AACD-769738C63D52 Q54098584-20CB3247-6C8C-4EB9-88FE-A491B79D7A8F Q54942168-B37CC58D-1D4C-4687-94E6-000F38A4F2F9 Q54977714-873F6006-7932-4BE9-8021-C74FD17E21CB Q58694216-9A850ED7-E106-47C0-B59E-A937A16A72E3

P2860

Stat3 inhibitor Stattic exhibits potent antitumor activity and induces chemo- and radio-sensitivity in nasopharyngeal carcinoma

http://www.wikidata.org/entity/Q34575479

description

2013 nî lūn-bûn

@nan

2013 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2013 թվականի հունվարին հրատարակված գիտական հոդված

@hy

2013年の論文

@ja

2013年論文

@yue

2013年論文

@zh-hant

2013年論文

@zh-hk

2013年論文

@zh-mo

2013年論文

@zh-tw

2013年论文

@wuu

name

Stat3 inhibitor Stattic exhibi ...... ty in nasopharyngeal carcinoma

@ast

Stat3 inhibitor Stattic exhibi ...... ty in nasopharyngeal carcinoma

@en

Stat3 inhibitor Stattic exhibi ...... ty in nasopharyngeal carcinoma

@nl

type

label

Stat3 inhibitor Stattic exhibi ...... ty in nasopharyngeal carcinoma

@ast

Stat3 inhibitor Stattic exhibi ...... ty in nasopharyngeal carcinoma

@en

Stat3 inhibitor Stattic exhibi ...... ty in nasopharyngeal carcinoma

@nl

prefLabel

Stat3 inhibitor Stattic exhibi ...... ty in nasopharyngeal carcinoma

@ast

Stat3 inhibitor Stattic exhibi ...... ty in nasopharyngeal carcinoma

@en

Stat3 inhibitor Stattic exhibi ...... ty in nasopharyngeal carcinoma

@nl

P1433

Q34575479-AA07D1F9-1323-494F-8EE9-56AD97909E14

P1476

Q34575479-640CC453-068E-4ADE-8156-A814EF33D224

P2093

Q34575479-93005273-7365-4971-93F6-E93D0C9EABC0

Q34575479-D0D7DA95-CE22-4033-9A37-0B69F54BBD2F

P2860

Q34575479-057D6E61-948F-444E-AE20-52C91E4B5DF4

Q34575479-082D8C45-626E-468C-9861-FA2ACD08DF63

Q34575479-0DC39FAC-FD1C-4669-90D6-B9A17E4274C7

Q34575479-10BC9290-D442-40AE-9AA5-38C69883ACAB

Q34575479-1538B9C9-909C-45BF-B81F-39DB4B934AEB

Q34575479-18D0C0ED-644A-4966-AA3D-EF4B95B1E92B

Q34575479-1D6F6094-3A7F-4BD8-8E91-985DA34342A9

Q34575479-2D926F34-EEE7-45A3-966C-5D3B1309CE8E

Q34575479-36665D53-1726-480E-BCF3-987DCE59B433

Q34575479-4075BA3E-D356-414D-A7D0-E722D95085AF

P304

Q34575479-92A02E46-8CD3-4B8F-B52C-783592746DE8

P31

Q34575479-5F9BA199-E272-4488-9C28-16FE2BC0FEC2

P356

Q34575479-A05C14E8-425B-4A26-93EF-04F47A281D81

P407

Q34575479-2334947C-69F5-4B6A-A5CB-F33F3834419A

P433

Q34575479-AE7EF352-2141-40EB-9D20-93879523AF8B

P478

Q34575479-D1619A75-148B-4E62-8B0F-1A2F993DA9FE

P50

Q34575479-BB64E411-F13A-446A-9C97-656C81E04CE0

Q34575479-EDE850EF-C6B4-4AF9-9AE7-2F6245019587

P577

Q34575479-A9E0F983-72E9-4AD6-A3B7-9DF6E822D8BC

P5875

Q34575479-8509E2C5-AA96-47EA-B59F-BBE2B986CC6F

P698

Q34575479-96A66C9B-42F2-4D6B-97FF-2A180471E801

P932

Q34575479-BE889D8D-7FC9-4ACB-ADBC-1DE1B305A394

P356

JOURNAL.PONE.0054565

P1433

P1476

Stat3 inhibitor Stattic exhibi ...... ty in nasopharyngeal carcinoma

@en

P2093

Francois X Claret

http://www.w3.org/2001/XMLSchema#string

Ronghua Zhang

http://www.w3.org/2001/XMLSchema#string

P2860

Three-dimensional structure of the Stat3beta homodimer bound to DNA

Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis

Chemical probes that competitively and selectively inhibit Stat3 activation

Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6

Deciphering the molecular genetic basis of NPC through molecular, cytogenetic, and epigenetic approaches

The STATs of cancer--new molecular targets come of age

Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE

Stattic: a small-molecule inhibitor of STAT3 activation and dimerization.

Selective chemical probe inhibitor of Stat3, identified through structure-based virtual screening, induces antitumor activity.

A low-molecular-weight compound discovered through virtual database screening inhibits Stat3 function in breast cancer cells.

P304

e54565

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1371/JOURNAL.PONE.0054565

http://www.w3.org/2001/XMLSchema#string

P407

P433

1

http://www.w3.org/2001/XMLSchema#string

P478

8

http://www.w3.org/2001/XMLSchema#string

P50

P577

2013-01-29T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

235402835

http://www.w3.org/2001/XMLSchema#string

P698

23382914

http://www.w3.org/2001/XMLSchema#string

P932

3558509

http://www.w3.org/2001/XMLSchema#string