An IRF8-binding promoter variant and AIRE control CHRNA1 promiscuous expression in thymus.
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Aire and T cell developmentTranscriptional regulation by AIRE: molecular mechanisms of central tolerancePrecision medicine in myasthenia graves: begin from the data precisionClinical features, pathogenesis, and treatment of myasthenia gravis: a supplement to the Guidelines of the German Neurological SocietyAntigen Presentation, Autoantigens, and Immune Regulation in Multiple Sclerosis and Other Autoimmune DiseasesRisk for myasthenia gravis maps to a (151) Pro→Ala change in TNIP1 and to human leukocyte antigen-B*08Positive and negative selection of the T cell repertoire: what thymocytes see (and don't see)Prioritizing genes of potential relevance to diseases affected by sex hormones: an example of myasthenia gravisSex bias in CNS autoimmune disease mediated by androgen control of autoimmune regulator.Aire regulates the expression of differentiation-associated genes and self-renewal of embryonic stem cellsThe differential disease regulomeGenetic-epigenetic dysregulation of thymic TSH receptor gene expression triggers thyroid autoimmunityThe role of X-linked FOXP3 in the autoimmune susceptibility of Turner Syndrome patientsVAV1 and BAFF, via NFκB pathway, are genetic risk factors for myasthenia gravis.Clinical and serologic parallels to APS-I in patients with thymomas and autoantigen transcripts in their tumors.Clues to immune tolerance: the monogenic autoimmune syndromesBoth polymorphic variable number of tandem repeats and autoimmune regulator modulate differential expression of insulin in human thymic epithelial cells.Impaired thymic tolerance to α-myosin directs autoimmunity to the heart in mice and humansYeast one-hybrid screen of a thymus epithelial library identifies ZBTB7A as a regulator of thymic insulin expressionAnalysis of serum miRNA profiles of myasthenia gravis patients.Intercommunication between the neuroendocrine and immune systems: focus on myasthenia gravis.John Newsom-Davis: clinician-scientist and so much more.T cells in the control of organ-specific autoimmunityMyasthenia gravis and neuromyelitis optica spectrum disorder: a multicenter study of 16 patientsBrd4 bridges the transcriptional regulators, Aire and P-TEFb, to promote elongation of peripheral-tissue antigen transcripts in thymic stromal cellsComplicating autoimmune diseases in myasthenia gravis: a review.Zinc transporter 8 autoantibodies and their association with SLC30A8 and HLA-DQ genes differ between immigrant and Swedish patients with newly diagnosed type 1 diabetes in the Better Diabetes Diagnosis studyRole of impaired central tolerance to α-myosin in inflammatory heart disease.RANKL-RANK interaction in immune regulatory systems.Mechanisms of an autoimmunity syndrome in mice caused by a dominant mutation in Aire.Estrogen-mediated downregulation of AIRE influences sexual dimorphism in autoimmune diseases.Aire employs a histone-binding module to mediate immunological tolerance, linking chromatin regulation with organ-specific autoimmunity.Ectopic expression of peripheral-tissue antigens in the thymic epithelium: probabilistic, monoallelic, misinitiatedStudies in mice deficient for the autoimmune regulator (Aire) and transgenic for the thyrotropin receptor reveal a role for Aire in tolerance for thyroid autoantigensHuman APECED; a Sick Thymus Syndrome?Hypothetical review: thymic aberrations and type-I interferons; attempts to deduce autoimmunizing mechanisms from unexpected clues in monogenic and paraneoplastic syndromes.Monogenic autoimmune diseases: insights into self-tolerance.An RNAi screen for Aire cofactors reveals a role for Hnrnpl in polymerase release and Aire-activated ectopic transcription.Whole-genome analysis in Korean patients with autoimmune myasthenia gravis.The auto-antigen repertoire in myasthenia gravis.
P2860
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P2860
An IRF8-binding promoter variant and AIRE control CHRNA1 promiscuous expression in thymus.
description
2007 nî lūn-bûn
@nan
2007 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
An IRF8-binding promoter varia ...... miscuous expression in thymus.
@ast
An IRF8-binding promoter varia ...... miscuous expression in thymus.
@en
An IRF8-binding promoter varia ...... miscuous expression in thymus.
@nl
type
label
An IRF8-binding promoter varia ...... miscuous expression in thymus.
@ast
An IRF8-binding promoter varia ...... miscuous expression in thymus.
@en
An IRF8-binding promoter varia ...... miscuous expression in thymus.
@nl
prefLabel
An IRF8-binding promoter varia ...... miscuous expression in thymus.
@ast
An IRF8-binding promoter varia ...... miscuous expression in thymus.
@en
An IRF8-binding promoter varia ...... miscuous expression in thymus.
@nl
P2093
P356
P1433
P1476
An IRF8-binding promoter varia ...... miscuous expression in thymus.
@en
P2093
Bruno Eymard
Bruno Kyewski
Christine Tranchant
Claire Vandiedonck
David Beeson
Francisco E Baralle
Franco Pagani
Henri-Jean Garchon
Matthieu Giraud
Matthieu Lévi-Strauss
P2888
P304
P356
10.1038/NATURE06066
P407
P577
2007-08-08T00:00:00Z
P6179
1037113719