Stable rhodopsin/arrestin complex leads to retinal degeneration in a transgenic mouse model of autosomal dominant retinitis pigmentosa.
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Accumulation of rhodopsin in late endosomes triggers photoreceptor cell degenerationImpaired photoreceptor protein transport and synaptic transmission in a mouse model of Bardet-Biedl syndromeConstitutively active rhodopsin and retinal diseaseNegative regulation of the novel norpA(P24) suppressor, diehard4, in the endo-lysosomal trafficking underlies photoreceptor cell degenerationRhodopsin: the functional significance of asn-linked glycosylation and other post-translational modificationsQ344ter mutation causes mislocalization of rhodopsin molecules that are catalytically active: a mouse model of Q344ter-induced retinal degeneration.Effect of g protein-coupled receptor kinase 1 (Grk1) overexpression on rod photoreceptor cell viabilityConstituents of bile, bilirubin and TUDCA, protect against oxidative stress-induced retinal degenerationPhotoactivation-induced instability of rhodopsin mutants T4K and T17M in rod outer segments underlies retinal degeneration in X. laevis transgenic models of retinitis pigmentosaInduction of the unfolded protein response by constitutive G-protein signaling in rod photoreceptor cells.Dysfunction of heterotrimeric kinesin-2 in rod photoreceptor cells and the role of opsin mislocalization in rapid cell death.A novel form of transducin-dependent retinal degeneration: accelerated retinal degeneration in the absence of rod transducinLight regulates the ciliary protein transport and outer segment disc renewal of mammalian photoreceptors.G protein-coupled receptor kinases: more than just kinases and not only for GPCRsAlternative pathway of cell death in Drosophila mediated by NF-κB transcription factor RelishDark-adapted response threshold of OFF ganglion cells is not set by OFF bipolar cells in the mouse retinaRole of rhodopsin and arrestin phosphorylation in retinal degeneration of DrosophilaFunctional comparison of rod and cone Gα(t) on the regulation of light sensitivity.Visual arrestin interaction with clathrin adaptor AP-2 regulates photoreceptor survival in the vertebrate retina.Effect of Rhodopsin Phosphorylation on Dark Adaptation in Mouse Rods.Regulation of arrestin binding by rhodopsin phosphorylation level.Usher syndromes due to MYO7A, PCDH15, USH2A or GPR98 mutations share retinal disease mechanism.Monomeric rhodopsin is the minimal functional unit required for arrestin binding.Caspase-cleaved arrestin-2 and BID cooperatively facilitate cytochrome C release and cell death.Hsp90 inhibition protects against inherited retinal degeneration.Separation of photoreceptor cell compartments in mouse retina for protein analysis.Rhodopsin homeostasis and retinal degeneration: lessons from the fly.Gene expression profiling of light-induced retinal degeneration in phototransduction gene knockout mice.Two pathways of rod photoreceptor cell death induced by elevated cGMP.Biochemical Measurements of Free Opsin in Macular Degeneration Eyes: Examining the 11-CIS Retinal Deficiency Hypothesis of Delayed Dark Adaptation (An American Ophthalmological Society Thesis).Rapid degeneration of rod photoreceptors expressing self-association-deficient arrestin-1 mutant.Arrestins in apoptosis.Adaptor protein-2 interaction with arrestin regulates GPCR recycling and apoptosis.The molecular and cellular basis of rhodopsin retinitis pigmentosa reveals potential strategies for therapy.
P2860
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P2860
Stable rhodopsin/arrestin complex leads to retinal degeneration in a transgenic mouse model of autosomal dominant retinitis pigmentosa.
description
2006 nî lūn-bûn
@nan
2006 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
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2006年学术文章
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2006年学术文章
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2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
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2006年學術文章
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name
Stable rhodopsin/arrestin comp ...... dominant retinitis pigmentosa.
@ast
Stable rhodopsin/arrestin comp ...... dominant retinitis pigmentosa.
@en
Stable rhodopsin/arrestin comp ...... dominant retinitis pigmentosa.
@nl
type
label
Stable rhodopsin/arrestin comp ...... dominant retinitis pigmentosa.
@ast
Stable rhodopsin/arrestin comp ...... dominant retinitis pigmentosa.
@en
Stable rhodopsin/arrestin comp ...... dominant retinitis pigmentosa.
@nl
prefLabel
Stable rhodopsin/arrestin comp ...... dominant retinitis pigmentosa.
@ast
Stable rhodopsin/arrestin comp ...... dominant retinitis pigmentosa.
@en
Stable rhodopsin/arrestin comp ...... dominant retinitis pigmentosa.
@nl
P2093
P1476
Stable rhodopsin/arrestin comp ...... dominant retinitis pigmentosa
@en
P2093
Daniel Oprian
Francis A Concepcion
Jeannie Chen
Jiayan Chen
P304
11929-11937
P356
10.1523/JNEUROSCI.3212-06.2006
P407
P577
2006-11-01T00:00:00Z