Creation and screening of a multi-family bacterial oxidoreductase library to discover novel nitroreductases that efficiently activate the bioreductive prodrugs CB1954 and PR-104A.

Creation and screening of a multi-family bacterial oxidoreductase library to discover novel nitroreductases that efficiently activate the bioreductive prodrugs CB1954 and PR-104A.

Item
http://www.wikidata.org/entity/Q34582616
The Flavin Reductase MsuE Is a Novel Nitroreductase that Can Efficiently Activate Two Promising Next-Generation Prodrugs for Gene-Directed Enzyme Prodrug TherapyProgress and problems with the use of suicide genes for targeted cancer therapyPseudomonas aeruginosa MdaB and WrbA are water-soluble two-electron quinone oxidoreductases with the potential to defend against oxidative stressEscherichia coli NemA is an efficient chromate reductase that can be biologically immobilized to provide a cell free system for remediation of hexavalent chromium.Toward a high-throughput screening platform for directed evolution of enzymes that activate genotoxic prodrugs.A gain-of-function positive-selection expression plasmid that enables high-efficiency cloning.Azoreductases in drug metabolism.Enzyme/Prodrug Systems for Cancer Gene Therapy.Pseudomonas aeruginosa NfsB and nitro-CBI-DEI--a promising enzyme/prodrug combination for gene directed enzyme prodrug therapy.Evolutionary and molecular foundations of multiple contemporary functions of the nitroreductase superfamily.Evaluation of NfsA-like nitroreductases from Neisseria meningitidis and Bartonella henselae for enzyme-prodrug therapy, targeted cellular ablation, and dinitrotoluene bioremediation.
P2860

Creation and screening of a multi-family bacterial oxidoreductase library to discover novel nitroreductases that efficiently activate the bioreductive prodrugs CB1954 and PR-104A.

Item
http://www.wikidata.org/entity/Q34582616
description
2013 nî lūn-bûn
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2013 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Creation and screening of a mu ...... e prodrugs CB1954 and PR-104A.
@ast
Creation and screening of a mu ...... e prodrugs CB1954 and PR-104A.
@en
Creation and screening of a mu ...... e prodrugs CB1954 and PR-104A.
@nl
type
label
Creation and screening of a mu ...... e prodrugs CB1954 and PR-104A.
@ast
Creation and screening of a mu ...... e prodrugs CB1954 and PR-104A.
@en
Creation and screening of a mu ...... e prodrugs CB1954 and PR-104A.
@nl
prefLabel
Creation and screening of a mu ...... e prodrugs CB1954 and PR-104A.
@ast
Creation and screening of a mu ...... e prodrugs CB1954 and PR-104A.
@en
Creation and screening of a mu ...... e prodrugs CB1954 and PR-104A.
@nl
P1433
P1476
P2093
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P356
P1433
P1476
Creation and screening of a mu ...... e prodrugs CB1954 and PR-104A.
@en
P2093
P304
P31
P356
P407
P433
P478
P577
P5875
P698