Insulin rapidly stimulates phosphorylation of a 46-kDa membrane protein on tyrosine residues as well as phosphorylation of several soluble proteins in intact fat cells.
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Identification of phosphorylated 422(aP2) protein as pp15, the 15-kilodalton target of the insulin receptor tyrosine kinase in 3T3-L1 adipocytes.Glucocorticoid regulation of insulin receptor and substrate IRS-1 tyrosine phosphorylation in rat skeletal muscle in vivo.Monoclonal antibodies to the insulin receptor stimulate the intrinsic tyrosine kinase activity by cross-linking receptor moleculesReversibility of defective adipocyte insulin receptor kinase activity in non-insulin-dependent diabetes mellitus. Effect of weight loss.Insulin receptor substrate 1 mediates insulin and insulin-like growth factor I-stimulated maturation of Xenopus oocytesIncreasing cAMP attenuates activation of mitogen-activated protein kinase.The insulin receptor: structure and function.Further evidence for a two-step model of glucose-transport regulation. Inositol phosphate-oligosaccharides regulate glucose-carrier activity.The insulin receptor and the molecular mechanism of insulin action.Inhibition of insulin-dependent lipogenesis and anti-lipolysis by protein tyrosine kinase inhibitors.The insulinomimetic agents H2O2 and vanadate stimulate tyrosine phosphorylation of potential target proteins for the insulin receptor kinase in intact cells.Regulation of glucose carrier activity by AlCl3 and phospholipase C in fat-cells.Concanavalin A-induced receptor aggregation stimulates the tyrosine kinase activity of the insulin receptor in intact cells.Phorbol esters imitate in rat fat-cells the full effect of insulin on glucose-carrier translocation, but not on 3-O-methylglucose-transport activity.An insulin-sensitive cytosolic protein kinase accounts for the regulation of ATP citrate-lyase phosphorylation.Insulin and insulin-like growth factor 1 stimulate the phosphorylation on tyrosine of a 160 kDa cytosolic protein in 3T3-L1 adipocytes.Tyrosine-specific phosphorylation of calmodulin by the insulin receptor kinase purified from human placenta.Insulin-receptor phosphotyrosyl-protein phosphatases.Activation of mitogen-activated protein kinase and phosphatidylinositol 3'-kinase is not sufficient for the hormonal stimulation of glucose uptake, lipogenesis, or glycogen synthesis in 3T3-L1 adipocytes.An Mr 180,000 protein is an endogenous substrate for the insulin-receptor-associated tyrosine kinase in human placenta.Tyrosine phosphorylation of two cytosolic proteins of 50 kDa and 35 kDa in rat liver by insulin-receptor kinase in vitro.Insulin activates GTP binding to a 40 kDa protein in fat cells.
P2860
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P2860
Insulin rapidly stimulates phosphorylation of a 46-kDa membrane protein on tyrosine residues as well as phosphorylation of several soluble proteins in intact fat cells.
description
1987 nî lūn-bûn
@nan
1987 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1987 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1987年の論文
@ja
1987年論文
@yue
1987年論文
@zh-hant
1987年論文
@zh-hk
1987年論文
@zh-mo
1987年論文
@zh-tw
1987年论文
@wuu
name
Insulin rapidly stimulates pho ...... proteins in intact fat cells.
@ast
Insulin rapidly stimulates pho ...... proteins in intact fat cells.
@en
Insulin rapidly stimulates pho ...... proteins in intact fat cells.
@nl
type
label
Insulin rapidly stimulates pho ...... proteins in intact fat cells.
@ast
Insulin rapidly stimulates pho ...... proteins in intact fat cells.
@en
Insulin rapidly stimulates pho ...... proteins in intact fat cells.
@nl
prefLabel
Insulin rapidly stimulates pho ...... proteins in intact fat cells.
@ast
Insulin rapidly stimulates pho ...... proteins in intact fat cells.
@en
Insulin rapidly stimulates pho ...... proteins in intact fat cells.
@nl
P2093
P2860
P356
P1476
Insulin rapidly stimulates pho ...... proteins in intact fat cells.
@en
P2093
P2860
P304
P356
10.1073/PNAS.84.1.113
P407
P577
1987-01-01T00:00:00Z