Action potential generation requires a high sodium channel density in the axon initial segment.
about
Axons amplify somatic incomplete spikes into uniform amplitudes in mouse cortical pyramidal neuronsAssociation between tetrodotoxin resistant channels and lipid rafts regulates sensory neuron excitabilityIon channel clustering at the axon initial segment and node of Ranvier evolved sequentially in early chordatesNeuroML: a language for describing data driven models of neurons and networks with a high degree of biological detailAdaptive evolution of voltage-gated sodium channels: the first 800 million yearsActivity-dependent regulation of synapses by retrograde messengersElectrogenic tuning of the axon initial segmentGABA neurons and the mechanisms of network oscillations: implications for understanding cortical dysfunction in schizophreniaAxon Initial Segment Cytoskeleton: Architecture, Development, and Role in Neuron PolarityFunctional implications of axon initial segment cytoskeletal disruption in strokeMechanisms of sodium channel clustering and its influence on axonal impulse conductionNeuronal morphology goes digital: a research hub for cellular and system neuroscienceAnatomy and physiology of the thick-tufted layer 5 pyramidal neuronQuantitative description of ion transport via plasma membrane of yeast and small cellsDynamics of Kv1 channel transport in axonsStructural and Functional Plasticity at the Axon Initial SegmentER Stress-Mediated Signaling: Action Potential and Ca(2+) as Key PlayersImaging with organic indicators and high-speed charge-coupled device cameras in neurons: some applications where these classic techniques have advantagesIκBα is not required for axon initial segment assemblySpikelets in Pyramidal Neurons: Action Potentials Initiated in the Axon Initial Segment That Do Not Activate the SomaModelling the Effects of Electrical Coupling between Unmyelinated Axons of Brainstem Neurons Controlling Rhythmic ActivityDistal spike initiation zone location estimation by morphological simulation of ionic current filtering demonstrated in a novel model of an identified Drosophila motoneuronEnd-binding proteins EB3 and EB1 link microtubules to ankyrin G in the axon initial segmentOpposing Effects on NaV1.2 Function Underlie Differences Between SCN2A Variants Observed in Individuals With Autism Spectrum Disorder or Infantile SeizuresMyelin Loss and Axonal Ion Channel Adaptations Associated with Gray Matter Neuronal HyperexcitabilityThe development and modelling of devices and paradigms for transcranial magnetic stimulationSynthesis and biological evaluation of a fluorescent analog of phenytoin as a potential inhibitor of neuropathic pain and imaging agent.Spike-threshold adaptation predicted by membrane potential dynamics in vivo.An investigation of dendritic delay in octopus cells of the mammalian cochlear nucleus.A threshold equation for action potential initiation.Axon-somatic back-propagation in detailed models of spinal alpha motoneuronsAxon initial segment dysfunction in a mouse model of genetic epilepsy with febrile seizures plus.Experimental and computational evidence for an essential role of NaV1.6 in spike initiation at stretch-sensitive colorectal afferent endingsDiffusion fMRI detects white-matter dysfunction in mice with acute optic neuritisStochastically gating ion channels enable patterned spike firing through activity-dependent modulation of spike probabilityAutonomous initiation and propagation of action potentials in neurons of the subthalamic nucleus.Converging on the origins of axonal ion channel clustering.Hyperphosphorylated tau causes reduced hippocampal CA1 excitability by relocating the axon initial segment.Ion channel density regulates switches between regular and fast spiking in soma but not in axons.Disruption of the axon initial segment cytoskeleton is a new mechanism for neuronal injury.
P2860
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P2860
Action potential generation requires a high sodium channel density in the axon initial segment.
description
2008 nî lūn-bûn
@nan
2008 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Action potential generation re ...... y in the axon initial segment.
@ast
Action potential generation re ...... y in the axon initial segment.
@en
Action potential generation re ...... y in the axon initial segment.
@nl
type
label
Action potential generation re ...... y in the axon initial segment.
@ast
Action potential generation re ...... y in the axon initial segment.
@en
Action potential generation re ...... y in the axon initial segment.
@nl
prefLabel
Action potential generation re ...... y in the axon initial segment.
@ast
Action potential generation re ...... y in the axon initial segment.
@en
Action potential generation re ...... y in the axon initial segment.
@nl
P2093
P356
P1433
P1476
Action potential generation re ...... y in the axon initial segment.
@en
P2093
Björn M Kampa
Greg J Stuart
Maarten H P Kole
Peter C Ruben
Stephen R Williams
Susanne U Ilschner
P2860
P2888
P304
P356
10.1038/NN2040
P407
P577
2008-01-20T00:00:00Z