Insights into the serine protease mechanism from atomic resolution structures of trypsin reaction intermediates. - Wikidata - wikimedia - TriplyDB

Insights into the serine protease mechanism from atomic resolution structures of trypsin reaction intermediates.

Insights into the serine protease mechanism from atomic resolution structures of trypsin reaction intermediates.

http://www.wikidata.org/entity/Q34598232

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Autosomal-recessive posterior microphthalmos is caused by mutations in PRSS56, a gene encoding a trypsin-like serine protease Rigidification of a Flexible Protease Inhibitor Variant upon Binding to Trypsin Structural basis for intramembrane proteolysis by rhomboid serine proteases Structure of a serine protease poised to resynthesize a peptide bond Differential P1 arginine and lysine recognition in the prototypical proprotein convertase Kex2 Crystal structure of the VP4 protease from infectious pancreatic necrosis virus reveals the acyl-enzyme complex for an intermolecular self-cleavage reaction Structural basis for accelerated cleavage of bovine pancreatic trypsin inhibitor (BPTI) by human mesotrypsin Crystal Structure of Fatty Acid Amide Hydrolase Bound to the Carbamate Inhibitor URB597: Discovery of a Deacylating Water Molecule and Insight into Enzyme Inactivation Determinants of Affinity and Proteolytic Stability in Interactions of Kunitz Family Protease Inhibitors with Mesotrypsin Structural Insight into Serine Protease Rv3671c that Protects M. tuberculosis from Oxidative and Acidic Stress The catalytic aspartate is protonated in the Michaelis complex formed between trypsin and an in vitro evolved substrate-like inhibitor: a refined mechanism of serine protease action Different active-site loop orientation in serine hydrolases versus acyltransferases Crystal Structure of a Viral Protease Intramolecular Acyl-enzyme Complex: INSIGHTS INTO cis-CLEAVAGE AT THE VP4/VP3 JUNCTION OF TELLINA BIRNAVIRUS Functional and structural characterization of a thermostable acetyl esterase from Thermotoga maritima Presence versus absence of hydrogen bond donor Tyr-39 influences interactions of cationic trypsin and mesotrypsin with protein protease inhibitors Conformational flexibility in the catalytic triad revealed by the high-resolution crystal structure ofStreptomyces erythraeustrypsin in an unliganded state Crystal structure of 6-guanidinohexanoyl trypsin near the optimum pH reveals the acyl-enzyme intermediate to be deacylated Atomic resolution crystal structure of HV-BBI protease inhibitor from amphibian skin in complex with bovine trypsin Investigation of Serine-Proteinase-Catalyzed Peptide Splicing in Analogues of Sunflower Trypsin Inhibitor 1 (SFTI-1)Mesotrypsin Has Evolved Four Unique Residues to Cleave Trypsin Inhibitors as Substrates An Acrobatic Substrate Metamorphosis Reveals a Requirement for Substrate Conformational Dynamics in Trypsin Proteolysis.Bare histidine-serine models: implication and impact of hydrogen bonding on nucleophilicity.The enzymes of β-lactam biosynthesis.Enumerating pathways of proton abstraction based on a spatial and electrostatic analysis of residues in the catalytic site.Handicap-Recover Evolution Leads to a Chemically Versatile, Nucleophile-Permissive Protease.Specific amyloid β clearance by a catalytic antibody construct.Serine protease acylation proceeds with a subtle re-orientation of the histidine ring at the tetrahedral intermediate.Catalytic mechanism of rhomboid protease GlpG probed by 3,4-dichloroisocoumarin and diisopropyl fluorophosphonate.Metal-dependent amyloid β-degrading catalytic antibody construct.Constant domain-regulated antibody catalysis.Characterization of the macrocyclase involved in the biosynthesis of RiPP cyclic peptides in plants.Analysis of residue conformations in peptides in Cambridge structural database and protein-peptide structural complexes.A tetrahedral transition state at the active sites of the 20S proteasome is coupled to opening of the alpha-ring channel.Atomic resolution structure of serine protease proteinase K at ambient temperature.SGNH hydrolase-type esterase domain containing Cbes-AcXE2: a novel and thermostable acetyl xylan esterase from Caldicellulosiruptor bescii.Structural basis of ribosomal peptide macrocyclization in plants.

P2860

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P2860

Insights into the serine protease mechanism from atomic resolution structures of trypsin reaction intermediates.

http://www.wikidata.org/entity/Q34598232

description

2006 nî lūn-bûn

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2006 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2006 թվականի ապրիլին հրատարակված գիտական հոդված

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2006年の論文

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2006年学术文章

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2006年学术文章

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2006年学术文章

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2006年学术文章

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2006年学术文章

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2006年學術文章

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name

Insights into the serine prote ...... rypsin reaction intermediates.

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Insights into the serine prote ...... rypsin reaction intermediates.

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Insights into the serine prote ...... rypsin reaction intermediates.

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type

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Insights into the serine prote ...... rypsin reaction intermediates.

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Insights into the serine prote ...... rypsin reaction intermediates.

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Insights into the serine prote ...... rypsin reaction intermediates.

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Insights into the serine prote ...... rypsin reaction intermediates.

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Insights into the serine prote ...... rypsin reaction intermediates.

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Insights into the serine prote ...... rypsin reaction intermediates.

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PNAS.0601910103

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Proceedings of the National Academy of Sciences of the United States of America

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Insights into the serine prote ...... rypsin reaction intermediates.

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P2093

Chia-Jung Karen Lu

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Daniel E Koshland

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Evette S Radisky

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Justin M Lee

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P2860

Improved methods for building protein models in electron density maps and the location of errors in these models

High-resolution structures of three new trypsin-squash-inhibitor complexes: a detailed comparison with other trypsins and their complexes

The crystal structures of the complexes between bovine beta-trypsin and ten P1 variants of BPTI

High-resolution structure of a potent, cyclic proteinase inhibitor from sunflower seeds

Substitutions at the P(1) position in BPTI strongly affect the association energy with serine proteinases

Transition state structure of purine nucleoside phosphorylase and principles of atomic motion in enzymatic catalysis

X-ray snapshots of serine protease catalysis reveal a tetrahedral intermediate

Catalysis by hen egg-white lysozyme proceeds via a covalent intermediate

X-ray structure of a serine protease acyl-enzyme complex at 0.95-A resolution

A clogged gutter mechanism for protease inhibitors.

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