Functional assessment of perforin C2 domain mutations illustrates the critical role for calcium-dependent lipid binding in perforin cytotoxic function

Functional assessment of perforin C2 domain mutations illustrates the critical role for calcium-dependent lipid binding in perforin cytotoxic function

Item
http://www.wikidata.org/entity/Q34598862
A Pore Idea: the ion conduction pathway of TMEM16/ANO proteins is composed partly of lipidA novel Dutch mutation in UNC13D reveals an essential role of the C2B domain in munc13-4 functionPerforin rapidly induces plasma membrane phospholipid flip-flopPerforin: structure, function, and role in human immunopathology.Modulatory effects of perforin gene dosage on pathogen-associated blood-brain barrier (BBB) disruption.Primary and secondary hemophagocytic lymphohistiocytosis: clinical features, pathogenesis and therapy.Enhancement of NK cells proliferation and function by Shikonin.Real-time detection of CTL function reveals distinct patterns of caspase activation mediated by Fas versus granzyme B.Perforin gene transfer into hematopoietic stem cells improves immune dysregulation in murine models of perforin deficiencyFinding a Balance between Protection and Pathology: The Dual Role of Perforin in Human Disease.Intracellular trafficking of perforin: to thwart a killer.Human perforin gene variation is geographically distributed.
P2860

Functional assessment of perforin C2 domain mutations illustrates the critical role for calcium-dependent lipid binding in perforin cytotoxic function

Item
http://www.wikidata.org/entity/Q34598862
description
2008 nî lūn-bûn
@nan
2008 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
name
Functional assessment of perfo ...... in perforin cytotoxic function
@ast
Functional assessment of perfo ...... in perforin cytotoxic function
@en
Functional assessment of perfo ...... in perforin cytotoxic function
@nl
type
label
Functional assessment of perfo ...... in perforin cytotoxic function
@ast
Functional assessment of perfo ...... in perforin cytotoxic function
@en
Functional assessment of perfo ...... in perforin cytotoxic function
@nl
prefLabel
Functional assessment of perfo ...... in perforin cytotoxic function
@ast
Functional assessment of perfo ...... in perforin cytotoxic function
@en
Functional assessment of perfo ...... in perforin cytotoxic function
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
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P5875
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P1476
Functional assessment of perfo ...... in perforin cytotoxic function
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P2093
P2860
P304
P31
P356
10.1182/BLOOD-2008-08-172924
P407
P433
P478
P50
P577
P5875
P698
P921
P932