The carnitine transporter SLC22A5 is not a general drug transporter, but it efficiently translocates mildronate.
about
Transport mechanisms and their pathology-induced regulation govern tyrosine kinase inhibitor delivery in rheumatoid arthritisDifferent involvement of promoter methylation in the expression of organic cation/carnitine transporter 2 (OCTN2) in cancer cell linesImportance of the novel organic cation transporter 1 for tyrosine kinase inhibition by saracatinib in rheumatoid arthritis synovial fibroblasts.Selective regulation of cardiac organic cation transporter novel type 2 (OCTN2) in dilated cardiomyopathyAssessment of the role of renal organic anion transporters in drug-induced nephrotoxicity.Chronic administration of a leupeptin-derived calpain inhibitor fails to ameliorate severe muscle pathology in a canine model of duchenne muscular dystrophyInhibition of OCTN2-mediated transport of carnitine by etoposide.Phytochemicals Mediate the Expression and Activity of OCTN2 as Activators of the PPARγ/RXRα Pathway.Renal transport of organic anions and cations.OCTN cation transporters in health and disease: role as drug targets and assay development.Pharmacokinetic aspects of the anti-epileptic drug substance vigabatrin: focus on transporter interactions.Muscle carnitine availability plays a central role in regulating fuel metabolism in the rodent.Renal Drug Transporters and Drug Interactions.Characterization of Calu-3 cell monolayers as a model of bronchial epithelial transport: organic cation interaction studies.OAT2 catalyses efflux of glutamate and uptake of orotic acid.Rectal absorption of vigabatrin, a substrate of the proton coupled amino acid transporter (PAT1, Slc36a1), in rats.Carnitine and γ-Butyrobetaine Stimulate Elimination of Meldonium due to Competition for OCTN2-mediated Transport.Mildronate treatment alters γ-butyrobetaine and l-carnitine concentrations in healthy volunteers.A fatty acid analogue targeting mitochondria exerts a plasma triacylglycerol lowering effect in rats with impaired carnitine biosynthesis.SLC22A13 catalyses unidirectional efflux of aspartate and glutamate at the basolateral membrane of type A intercalated cells in the renal collecting ductWhole grain intake associated molecule 5-aminovaleric acid betaine decreases β-oxidation of fatty acids in mouse cardiomyocytes
P2860
Q28484465-DB2A4FBC-8352-4448-ADEB-6622182EE48BQ28534471-23B9D598-EC73-400B-BE25-D9DA1C7B7D90Q30313218-97E0974E-2B93-4AC4-8A15-25CDAEF4D5F9Q35071386-9B0B96F5-56C0-48CC-BFBC-CAA9E35BD261Q35155913-B6D7267C-0D5B-4FB7-A7A3-21D5C33C94F9Q35660362-CD0A125D-EB7D-400A-80BD-87F4DD4DA9AEQ36302949-9D964981-CE40-4CE3-93B3-A1A131F897B5Q37048770-D75CBE72-F610-4E0D-B404-521E207360C8Q38111725-2DA140B1-2810-4E7F-A253-06F8AC75988CQ38114865-86072EC4-E9C3-43D3-9515-4A83650B0237Q38261962-5A31CCE9-CA66-4BE2-9551-1A0183CD8987Q38730157-56A01D69-8F4F-45FD-BE17-87EF6362169CQ39140289-1FA5E171-FCC0-42F8-81FB-18D4B424438CQ39262937-5639FAAA-D038-454A-9361-564D1CA77224Q39568785-0F61BC47-FE03-4E46-9912-33528F2A731DQ48657505-8499FFD6-439C-4D4A-A150-919406A40D6DQ51007182-A9771771-E618-4EBF-8B0C-0942702A986FQ51428083-0A6BE618-9AFF-410A-924A-803D1AF7992FQ55235061-2A952546-11CC-4E15-BB07-2E7CE1D76BD4Q56593638-8B3C0751-549C-46B0-9140-C5909F238B4EQ58695781-D76D8DA3-A23F-4128-967B-C6467061D0D0
P2860
The carnitine transporter SLC22A5 is not a general drug transporter, but it efficiently translocates mildronate.
description
2008 nî lūn-bûn
@nan
2008 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
The carnitine transporter SLC2 ...... ently translocates mildronate.
@ast
The carnitine transporter SLC2 ...... ently translocates mildronate.
@en
The carnitine transporter SLC2 ...... ently translocates mildronate.
@nl
type
label
The carnitine transporter SLC2 ...... ently translocates mildronate.
@ast
The carnitine transporter SLC2 ...... ently translocates mildronate.
@en
The carnitine transporter SLC2 ...... ently translocates mildronate.
@nl
prefLabel
The carnitine transporter SLC2 ...... ently translocates mildronate.
@ast
The carnitine transporter SLC2 ...... ently translocates mildronate.
@en
The carnitine transporter SLC2 ...... ently translocates mildronate.
@nl
P2093
P356
P1476
The carnitine transporter SLC2 ...... ently translocates mildronate.
@en
P2093
Andreas Geerts
Christian Fork
Dirk Gründemann
Edgar Schömig
Markus Bach
Silke Grigat
Stefan Golz
P304
P356
10.1124/DMD.108.023929
P577
2008-11-03T00:00:00Z