ORAI1-mediated calcium influx is required for human cytotoxic lymphocyte degranulation and target cell lysis - Wikidata - wikimedia - TriplyDB

ORAI1-mediated calcium influx is required for human cytotoxic lymphocyte degranulation and target cell lysis

ORAI1-mediated calcium influx is required for human cytotoxic lymphocyte degranulation and target cell lysis

http://www.wikidata.org/entity/Q34602870

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SOCE and cancer: Recent progress and new perspectives Ion channels and transporters in lymphocyte function and immunity Cell biological steps and checkpoints in accessing NK cell cytotoxicity Molecular regulation of CRAC channels and their role in lymphocyte function Visualization of cytolytic T cell differentiation and granule exocytosis with T cells from mice expressing active fluorescent granzyme B STIM1/Orai1 coiled-coil interplay in the regulation of store-operated calcium entry Diseases caused by mutations in ORAI1 and STIM1 STIM1- and Orai1-mediated Ca(2+) oscillation orchestrates invadopodium formation and melanoma invasion.Clinical and Molecular Heterogeneity of RTEL1 Deficiency CD4⁺ and CD8⁺ T cell-dependent antiviral immunity requires STIM1 and STIM2.Flow cytometry enables a high-throughput homogeneous fluorescent antibody-binding assay for cytotoxic T cell lytic granule exocytosis.Immune synapse: conductor of orchestrated organelle movement.A high-throughput phenotypic screen of cytotoxic T lymphocyte lytic granule exocytosis reveals candidate immunosuppressants.ADP-ribose/TRPM2-mediated Ca2+ signaling is essential for cytolytic degranulation and antitumor activity of natural killer cells.Antiviral and regulatory T cell immunity in a patient with stromal interaction molecule 1 deficiency.VAMP8-dependent fusion of recycling endosomes with the plasma membrane facilitates T lymphocyte cytotoxicity.Variations in ORAI1 Gene Associated with Kawasaki Disease A novel mutation in ORAI1 presenting with combined immunodeficiency and residual T-cell function.Calcium Dynamics of Ex Vivo Long-Term Cultured CD8+ T Cells Are Regulated by Changes in Redox Metabolism.Omenn syndrome associated with a functional reversion due to a somatic second-site mutation in CARD11 deficiency.Human NK cell lytic granules and regulation of their exocytosis Mutations of the Ca2+-sensing stromal interaction molecule STIM1 regulate Ca2+ influx by altered oligomerization of STIM1 and by destabilization of the Ca2+ channel Orai1 Divalent cation signaling in immune cells Natural killer cells and single nucleotide polymorphisms of specific ion channels and receptor genes in myalgic encephalomyelitis/chronic fatigue syndrome.Ion channels in innate and adaptive immunity Partial defects of T-cell development associated with poor T-cell function.Leukocyte function antigen-1, kindlin-3, and calcium flux orchestrate neutrophil recruitment during inflammation.Dysregulation of Protein Kinase Gene Expression in NK Cells from Chronic Fatigue Syndrome/Myalgic Encephalomyelitis Patients.Loss of DNAM-1 ligand expression by acute myeloid leukemia cells renders them resistant to NK cell killing.STIM1 and STIM2-mediated Ca(2+) influx regulates antitumour immunity by CD8(+) T cells Orais and STIMs: physiological mechanisms and disease Altered distribution and function of natural killer cells in murine and human Niemann-Pick disease type C1.Human immunodeficiency syndromes affecting human natural killer cell cytolytic activity.Emerging roles of Orai3 in pathophysiology.Ion channels and anti-cancer immunity.Natural killer cell deficiency.Molecular mechanisms of natural killer cell activation.The natural killer cell cytotoxic function is modulated by HIV-1 accessory proteins.Immunodeficiency due to defects in store-operated calcium entry.Physiological and pathophysiological functions of SOCE in the immune system.

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ORAI1-mediated calcium influx is required for human cytotoxic lymphocyte degranulation and target cell lysis

http://www.wikidata.org/entity/Q34602870

description

2011 nî lūn-bûn

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2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի փետրվարին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

ORAI1-mediated calcium influx ...... nulation and target cell lysis

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ORAI1-mediated calcium influx ...... nulation and target cell lysis

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ORAI1-mediated calcium influx ...... nulation and target cell lysis

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type

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ORAI1-mediated calcium influx ...... nulation and target cell lysis

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ORAI1-mediated calcium influx ...... nulation and target cell lysis

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ORAI1-mediated calcium influx ...... nulation and target cell lysis

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ORAI1-mediated calcium influx ...... nulation and target cell lysis

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ORAI1-mediated calcium influx ...... nulation and target cell lysis

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ORAI1-mediated calcium influx ...... nulation and target cell lysis

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Proceedings of the National Academy of Sciences of the United States of America

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ORAI1-mediated calcium influx ...... nulation and target cell lysis

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Andrea Maul-Pavicic

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Anne Rensing-Ehl

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Birthe Jessen

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Christie-Ann McCarl

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Cyril Fauriat

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Ilka Schulze

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Katsuhiko Mikoshiba

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Klaus Schwarz

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Markus Hufnagel

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P2860

STIM is a Ca2+ sensor essential for Ca2+-store-depletion-triggered Ca2+ influx

CRACM1 is a plasma membrane protein essential for store-operated Ca2+ entry

Ca(2+)-dependent and -independent activities of neural and non-neural synaptotagmins

STIM1, an essential and conserved component of store-operated Ca2+ channel function

Activation and expression of the nuclear factors of activated T cells, NFATp and NFATc, in human natural killer cells: regulation upon CD16 ligand binding

Defective cytotoxic lymphocyte degranulation in syntaxin-11 deficient familial hemophagocytic lymphohistiocytosis 4 (FHL4) patients

Analysis of natural killer-cell function in familial hemophagocytic lymphohistiocytosis (FHL): defective CD107a surface expression heralds Munc13-4 defect and discriminates between genetic subtypes of the disease

A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function

Jinx, an MCMV susceptibility phenotype caused by disruption of Unc13d: a mouse model of type 3 familial hemophagocytic lymphohistiocytosis

Definition of Munc13-homology-domains and characterization of a novel ubiquitously expressed Munc13 isoform

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