Genetic analyses of Schizosaccharomyces pombe dna2(+) reveal that dna2 plays an essential role in Okazaki fragment metabolism.
about
Activation of an alternative, rec12 (spo11)-independent pathway of fission yeast meiotic recombination in the absence of a DNA flap endonucleaseIsolation of human Dna2 endonuclease and characterization of its enzymatic propertiesBiochemical analysis of human Dna2Human Dna2 is a nuclear and mitochondrial DNA maintenance proteinOkazaki fragment processing-independent role for human Dna2 enzyme during DNA replicationIdentification of delta helicase as the bovine homolog of HUPF1: demonstration of an interaction with the third subunit of DNA polymerase delta.DNA replication meets genetic exchange: chromosomal damage and its repair by homologous recombinationEnzymatic properties of the Caenorhabditis elegans Dna2 endonuclease/helicase and a species-specific interaction between RPA and Dna2Mapping and mutation of the conserved DNA polymerase interaction motif (DPIM) located in the C-terminal domain of fission yeast DNA polymerase delta subunit Cdc27Contrasting effects of Elg1-RFC and Ctf18-RFC inactivation in the absence of fully functional RFC in fission yeastDynamic localization of an Okazaki fragment processing protein suggests a novel role in telomere replicationMutations in DNA replication genes reduce yeast life span.Bimodal interaction between replication-protein A and Dna2 is critical for Dna2 function both in vivo and in vitro.Significance of the dissociation of Dna2 by flap endonuclease 1 to Okazaki fragment processing in Saccharomyces cerevisiae.Rad52/Rad59-dependent recombination as a means to rectify faulty Okazaki fragment processing.Tripartite structure of Saccharomyces cerevisiae Dna2 helicase/endonucleaseOkazaki fragment processing: modulation of the strand displacement activity of DNA polymerase delta by the concerted action of replication protein A, proliferating cell nuclear antigen, and flap endonuclease-1.Reconstitution of eukaryotic lagging strand DNA replication.G-quadruplex nucleic acids and human diseasemcl1+, the Schizosaccharomyces pombe homologue of CTF4, is important for chromosome replication, cohesion, and segregation.Telomeres: structures in need of unwinding.The fission yeast pfh1(+) gene encodes an essential 5' to 3' DNA helicase required for the completion of S-phaseEvidence suggesting that Pif1 helicase functions in DNA replication with the Dna2 helicase/nuclease and DNA polymerase deltaThe human Bloom syndrome gene suppresses the DNA replication and repair defects of yeast dna2 mutants.The Saccharomyces cerevisiae Dna2 can function as a sole nuclease in the processing of Okazaki fragments in DNA replicationA Selective Small Molecule DNA2 Inhibitor for Sensitization of Human Cancer Cells to ChemotherapySequence, structure and functional diversity of PD-(D/E)XK phosphodiesterase superfamilyInteraction between APC and Fen1 during breast carcinogenesis.Flap endonuclease 1.Comprehensive mapping of the C-terminus of flap endonuclease-1 reveals distinct interaction sites for five proteins that represent different DNA replication and repair pathwaysDna2 is involved in CA strand resection and nascent lagging strand completion at native yeast telomeres.Human DNA2 possesses a cryptic DNA unwinding activity that functionally integrates with BLM or WRN helicases.Genetic and biochemical analyses of Pfh1 DNA helicase function in fission yeastFission yeast Dna2 is required for generation of the telomeric single-strand overhangGenetics of lagging strand DNA synthesis and maturation in fission yeast: suppression analysis links the Dna2-Cdc24 complex to DNA polymerase delta.The N-terminal 45-kDa domain of Dna2 endonuclease/helicase targets the enzyme to secondary structure DNAStudies on human DNA polymerase epsilon and GINS complex and their role in DNA replication.FEN1 ensures telomere stability by facilitating replication fork re-initiationInviability of a DNA2 deletion mutant is due to the DNA damage checkpoint.GSK-3β Homolog Rim11 and the Histone Deacetylase Complex Ume6-Sin3-Rpd3 Are Involved in Replication Stress Response Caused by Defects in Dna2.
P2860
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P2860
Genetic analyses of Schizosaccharomyces pombe dna2(+) reveal that dna2 plays an essential role in Okazaki fragment metabolism.
description
2000 nî lūn-bûn
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2000 թուականի Յուլիսին հրատարակուած գիտական յօդուած
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2000 թվականի հուլիսին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年论文
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name
Genetic analyses of Schizosaccharomyces pombe dna2
@nl
Genetic analyses of Schizosacc ...... n Okazaki fragment metabolism.
@ast
Genetic analyses of Schizosacc ...... n Okazaki fragment metabolism.
@en
type
label
Genetic analyses of Schizosaccharomyces pombe dna2
@nl
Genetic analyses of Schizosacc ...... n Okazaki fragment metabolism.
@ast
Genetic analyses of Schizosacc ...... n Okazaki fragment metabolism.
@en
prefLabel
Genetic analyses of Schizosaccharomyces pombe dna2
@nl
Genetic analyses of Schizosacc ...... n Okazaki fragment metabolism.
@ast
Genetic analyses of Schizosacc ...... n Okazaki fragment metabolism.
@en
P2093
P2860
P1433
P1476
Genetic analyses of Schizosacc ...... n Okazaki fragment metabolism.
@en
P2093
MacNeill SA
P2860
P304
P407
P577
2000-07-01T00:00:00Z