Transient receptor potential ion channel Trpm7 regulates exocrine pancreatic epithelial proliferation by Mg2+-sensitive Socs3a signaling in development and cancer. - Wikidata - wikimedia - TriplyDB

Transient receptor potential ion channel Trpm7 regulates exocrine pancreatic epithelial proliferation by Mg2+-sensitive Socs3a signaling in development and cancer.

Transient receptor potential ion channel Trpm7 regulates exocrine pancreatic epithelial proliferation by Mg2+-sensitive Socs3a signaling in development and cancer.

http://www.wikidata.org/entity/Q34611784

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The Role of nAChR and Calcium Signaling in Pancreatic Cancer Initiation and Progression Emergence of zebrafish models in oncology for validating novel anticancer drug targets and nanomaterials TRPM channels and magnesium in early embryonic development Translating discovery in zebrafish pancreatic development to human pancreatic cancer: biomarkers, targets, pathogenesis, and therapeutics Kinome-wide functional genomics screen reveals a novel mechanism of TNFα-induced nuclear accumulation of the HIF-1α transcription factor in cancer cells TRPM7 Histone deacetylase 1 is required for exocrine pancreatic epithelial proliferation in development and cancer.Targeting developmental regulators of zebrafish exocrine pancreas as a therapeutic approach in human pancreatic cancer.Aberrant over-expression of TRPM7 ion channels in pancreatic cancer: required for cancer cell invasion and implicated in tumor growth and metastasis Role of TRPM7 in Cancer: Potential as Molecular Biomarker and Therapeutic Target.Aberrantly Over-Expressed TRPM8 Channels in Pancreatic Adenocarcinoma: Correlation with Tumor Size/Stage and Requirement for Cancer Cells Invasion High expression of transient receptor potential channels in human breast cancer epithelial cells and tissues: correlation with pathological parameters.Silencing TRPM7 in mouse cortical astrocytes impairs cell proliferation and migration via ERK and JNK signaling pathways.Targeted silencing of TRPM7 ion channel induces replicative senescence and produces enhanced cytotoxicity with gemcitabine in pancreatic adenocarcinoma Regulation of TRPM7 Function by IL-6 through the JAK2-STAT3 Signaling Pathway.TRPM8 ion channel is aberrantly expressed and required for preventing replicative senescence in pancreatic adenocarcinoma: potential role of TRPM8 as a biomarker and target A key role for Mg(2+) in TRPM7's control of ROS levels during cell stress.Inhibition of cancer cell proliferation by midazolam by targeting transient receptor potential melastatin 7.TRPM7 and TRPM8 Ion Channels in Pancreatic Adenocarcinoma: Potential Roles as Cancer Biomarkers and Targets SNHG8 is identified as a key regulator of epstein-barr virus(EBV)-associated gastric cancer by an integrative analysis of lncRNA and mRNA expression Protons and Ca2+: ionic allies in tumor progression?Magnesium and its transporters in cancer: a novel paradigm in tumour development.Proton-sensitive cation channels and ion exchangers in ischemic brain injury: new therapeutic targets for stroke?Interaction of tumour cells with their microenvironment: ion channels and cell adhesion molecules. A focus on pancreatic cancer.Oncogenic role and therapeutic target of transient receptor potential melastatin 7 channel in malignancy.Cellular and Developmental Biology of TRPM7 Channel-Kinase: Implicated Roles in Cancer.Lidocaine suppresses glioma cell proliferation by inhibiting TRPM7 channels.Functional characterization of TRPM7 in nasopharyngeal carcinoma and its knockdown effects on tumorigenesis.Differential expression of TRPM7 in rat hepatoma and embryonic and adult hepatocytes.Transient receptor potential melastatin-related 7 channel is overexpressed in human pancreatic ductal adenocarcinomas and regulates human pancreatic cancer cell migration.TRPM7 channel regulates ox-LDL-induced proliferation and migration of vascular smooth muscle cells via MEK-ERK pathways.A Nonredundant Role for the TRPM6 Channel in Neural Tube Closure.Phylogenetic analysis and expression of zebrafish transient receptor potential melastatin family genes.Activation of Transient Receptor Potential Vanilloid 4 Promotes the Proliferation of Stem Cells in the Adult Hippocampal Dentate Gyrus.The kinase activity of the channel-kinase protein TRPM7 regulates stability and localization of the TRPM7 channel in polarized epithelial cells.

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P2860

Transient receptor potential ion channel Trpm7 regulates exocrine pancreatic epithelial proliferation by Mg2+-sensitive Socs3a signaling in development and cancer.

http://www.wikidata.org/entity/Q34611784

description

2010 nî lūn-bûn

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2010 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

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2010 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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Transient receptor potential i ...... ing in development and cancer.

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Transient receptor potential i ...... ing in development and cancer.

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Disease Models & Mechanisms

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Transient receptor potential i ...... ing in development and cancer.

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P2093

I-Chau Liang

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Nelson S Yee

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Weiqiang Zhou

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P2860

Core signaling pathways in human pancreatic cancers revealed by global genomic analyses

TRP-PLIK, a bifunctional protein with kinase and ion channel activities

Characterization of the protein kinase activity of TRPM7/ChaK1, a protein kinase fused to the transient receptor potential ion channel

LTRPC7 is a Mg.ATP-regulated divalent cation channel required for cell viability

Cyclin G1 has growth inhibitory activity linked to the ARF-Mdm2-p53 and pRb tumor suppressor pathways

Transient receptor potential channel TRPM8 is over-expressed and required for cellular proliferation in pancreatic adenocarcinoma.

Formation of the digestive system in zebrafish. II. Pancreas morphogenesis.

Organ size is limited by the number of embryonic progenitor cells in the pancreas but not the liver.

Coupled mutagenesis screens and genetic mapping in zebrafish.

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240-254

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10.1242/DMM.004564

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2

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4

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21183474

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3046099

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