The PET radioligand [11C]MePPEP binds reversibly and with high specific signal to cannabinoid CB1 receptors in nonhuman primate brain. - Wikidata - wikimedia - TriplyDB

The PET radioligand [11C]MePPEP binds reversibly and with high specific signal to cannabinoid CB1 receptors in nonhuman primate brain.

The PET radioligand [11C]MePPEP binds reversibly and with high specific signal to cannabinoid CB1 receptors in nonhuman primate brain.

http://www.wikidata.org/entity/Q34613459

about

Positron emission tomography imaging in multiple sclerosis-current status and future applications Analogs of JHU75528, a PET ligand for imaging of cerebral cannabinoid receptors (CB1): development of ligands with optimized lipophilicity and binding affinity [18F]MK-9470, a positron emission tomography (PET) tracer for in vivo human PET brain imaging of the cannabinoid-1 receptor Cannabinoid CB1 receptor immunoreactivity in the prefrontal cortex: Comparison of schizophrenia and major depressive disorder.Neuroimaging in Huntington's disease.PET radiotracers: crossing the blood-brain barrier and surviving metabolism [¹²⁵I]SD-7015 reveals fine modalities of CB₁ cannabinoid receptor density in the prefrontal cortex during progression of Alzheimer's disease Discovery and labeling of high-affinity 3,4-diarylpyrazolines as candidate radioligands for in vivo imaging of cannabinoid subtype-1 (CB1) receptors.Imaging and quantitation of cannabinoid CB1 receptors in human and monkey brains using (18)F-labeled inverse agonist radioligands.Test-retest reproducibility of cannabinoid-receptor type 1 availability quantified with the PET ligand [¹¹C]MePPEP.Evaluation of [11C]PipISB and [18F]PipISB in monkey as candidate radioligands for imaging brain cannabinoid type-1 receptors in vivo.Radiosynthesis and evaluation of an (18)F-labeled positron emission tomography (PET) radioligand for brain histamine subtype-3 receptors based on a nonimidazole 2-aminoethylbenzofuran chemotype.Positron emission tomography imaging using an inverse agonist radioligand to assess cannabinoid CB1 receptors in rodents.Synthesis, ex vivo evaluation, and radiolabeling of potent 1,5-diphenylpyrrolidin-2-one cannabinoid subtype-1 receptor ligands as candidates for in vivo imaging.Breast cancer resistance protein interacts with various compounds in vitro, but plays a minor role in substrate efflux at the blood-brain barrier.Quantitation of cannabinoid CB1 receptors in healthy human brain using positron emission tomography and an inverse agonist radioligand.In vitro and in vivo evaluation of (11)C-SD5024, a novel PET radioligand for human brain imaging of cannabinoid CB1 receptors.Synthesis and in vitro autoradiographic evaluation of a novel high-affinity radioiodinated ligand for imaging brain cannabinoid subtype-1 receptors.Synthetic strategies for radioligands for in vivo imaging of brain cannabinoid type-1 receptors.Dyskinesias in Parkinson's disease: views from positron emission tomography studies.Considerations in the Development of Reversibly Binding PET Radioligands for Brain Imaging.Synthesis and characterization in monkey of [11C]SP203 as a radioligand for imaging brain metabotropic glutamate 5 receptors.Development and characterization of a promising fluorine-18 labelled radiopharmaceutical for in vivo imaging of fatty acid amide hydrolase.18F-MK-9470 PET imaging of the type 1 cannabinoid receptor in prostate carcinoma: a pilot study.Approaches to quantify radioligands that wash out slowly from target organs Low brain CB1 receptor occupancy by a second generation CB1 receptor antagonist TM38837 in comparison with rimonabant in nonhuman primates: a PET study.Acute induction of anxiety in humans by delta-9-tetrahydrocannabinol related to amygdalar cannabinoid-1 (CB1) receptors.Pharmacokinetics of the cannabinoid receptor ligand [18 F]MK-9470 in the rat brain - Evaluation of models using microPET.Preclinical evaluation and quantification of [¹⁸F]MK-9470 as a radioligand for PET imaging of the type 1 cannabinoid receptor in rat brain.Synthesis and preclinical evaluation of [¹⁸F]FCHC for neuroimaging of fatty acid amide hydrolase.Automated one-step radiosynthesis of the CB1 receptor imaging agent [(18) F]MK-9470.Expression and localization of CB1R, NAPE-PLD, and FAAH in the vervet monkey nucleus accumbens.

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The PET radioligand [11C]MePPEP binds reversibly and with high specific signal to cannabinoid CB1 receptors in nonhuman primate brain.

http://www.wikidata.org/entity/Q34613459

description

2007 nî lūn-bûn

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2007 թուականի Մարտին հրատարակուած գիտական յօդուած

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2007 թվականի մարտին հրատարակված գիտական հոդված

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2007年の論文

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2007年学术文章

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2007年学术文章

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2007年学术文章

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2007年学术文章

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2007年学术文章

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2007年學術文章

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name

The PET radioligand [11C]MePPE ...... ors in nonhuman primate brain.

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The PET radioligand [11C]MePPE ...... ors in nonhuman primate brain.

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The PET radioligand [11C]MePPE ...... ors in nonhuman primate brain.

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The PET radioligand [11C]MePPE ...... ors in nonhuman primate brain.

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Neuropsychopharmacology

P1476

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P2093

Amira K Brown

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Amy K Chesterfield

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Christian C Felder

http://www.w3.org/2001/XMLSchema#string

Eyassu Chernet

http://www.w3.org/2001/XMLSchema#string

Fumihiko Yasuno

http://www.w3.org/2001/XMLSchema#string

Jinsoo Hong

http://www.w3.org/2001/XMLSchema#string

Johannes Tauscher

http://www.w3.org/2001/XMLSchema#string

John M Schaus

http://www.w3.org/2001/XMLSchema#string

Joseph H Krushinski

http://www.w3.org/2001/XMLSchema#string

Lee A Phebus

http://www.w3.org/2001/XMLSchema#string

P2860

Cannabinoid receptor localization in brain

A new look at the statistical model identification

Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

Endocannabinoids in appetite control and the treatment of obesity

International Union of Pharmacology. XXVII. Classification of cannabinoid receptors

Increased drug delivery to the brain by P-glycoprotein inhibition.

The neurobiology of cannabinoid analgesia.

Gene targets related to phospholipid and fatty acid metabolism in schizophrenia and other psychiatric disorders: an update.

Evidence for novel cannabinoid receptors.

In vivo imaging of the brain cannabinoid receptor.

P2888

P304

259-269

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scholarly article

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10.1038/SJ.NPP.1301402

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2

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33

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Christer Halldin

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2007-03-28T00:00:00Z

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6416936

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1005198182

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17392732

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cannabinoid receptor