Gene knockout and metabolome analysis of carnitine/organic cation transporter OCTN1.
about
From genetics of inflammatory bowel disease towards mechanistic insightsA mutation in SLC22A4 encoding an organic cation transporter expressed in the cochlea strial endothelium causes human recessive non-syndromic hearing loss DFNB60Organic cation transporter-mediated ergothioneine uptake in mouse neural progenitor cells suppresses proliferation and promotes differentiation into neurons.Detection of QTL controlling feed efficiency and excretion in chickens fed a wheat-based diet.Metabolomics reveals an essential role for peroxisome proliferator-activated receptor α in bile acid homeostasis.Identification of OCTN2 variants and their association with phenotypes of Crohn's disease in a Korean population.Wide tolerance to amino acids substitutions in the OCTN1 ergothioneine transporter.Food-derived hydrophilic antioxidant ergothioneine is distributed to the brain and exerts antidepressant effect in mice.Selenoneine, a novel selenium-containing compound, mediates detoxification mechanisms against methylmercury accumulation and toxicity in zebrafish embryo.Identification and determination of selenoneine, 2-selenyl-N α , N α , N α -trimethyl-L-histidine, as the major organic selenium in blood cells in a fish-eating population on remote Japanese IslandsAssociation study between OCTN1 functional haplotypes and Crohn's disease in a Korean population.The Anti-Oxidant Ergothioneine Augments the Immunomodulatory Function of TLR Agonists by Direct Action on Macrophages.Hijacking solute carriers for proton-coupled drug transport.Renal transport of organic anions and cations.OCTN cation transporters in health and disease: role as drug targets and assay development.Separation technique for the determination of highly polar metabolites in biological samples.Carnitine/Organic Cation Transporter OCTN1 Negatively Regulates Activation in Murine Cultured Microglial Cells.Functional and molecular effects of mercury compounds on the human OCTN1 cation transporter: C50 and C136 are the targets for potent inhibition.Usefulness of kidney slices for functional analysis of apical reabsorptive transporters.Role of organic cation/carnitine transporter 1 in uptake of phenformin and inhibitory effect on complex I respiration in mitochondria.Characterization of ergothionase from Burkholderia sp. HME13 and its application to enzymatic quantification of ergothioneine.Anaerobic Origin of Ergothioneine.Knockout of a putative ergothioneine transporter in Caenorhabditis elegans decreases lifespan and increases susceptibility to oxidative damage.Safety of synthetic l‐ergothioneine (Ergoneine®) as a novel food pursuant to Regulation (EC) No 258/97Distribution and accumulation of dietary ergothioneine and its metabolites in mouse tissues.Ergothioneine and melatonin attenuate oxidative stress and protect against learning and memory deficits in C57BL/6J mice treated with D-galactose.Biochemistry: The surprising history of an antioxidant.L503F variant of carnitine/organic cation transporter 1 efficiently transports metformin and other biguanides.A mushroom-derived amino acid, ergothioneine, is a potential inhibitor of inflammation-related DNA halogenation.Dietary Supplementation of Selenoneine-Containing Tuna Dark Muscle Extract Effectively Reduces Pathology of Experimental Colorectal Cancers in Mice
P2860
Q26824328-667AF22E-8C6C-4A18-8824-E94CB8841F22Q30357625-B0130E03-C6FA-4159-9EB2-364AF622448AQ35107315-B463928E-DCB8-402E-9C8E-94A0C83AF569Q36092760-75EC0F1D-0AAF-4F7D-8F00-A53D2200C15DQ36520380-9DA9B625-2B59-4FBD-8166-9E020AF1B5A8Q36674906-CFC09AED-0152-40BD-9C2F-7F90E11BBB71Q36817792-066C9B77-C8C4-4851-B52D-D7C0EB8D9C0EQ36830164-71FC19C8-3169-4D2A-B9E2-8A94C926BA0EQ37094021-50A5FC16-CC76-4621-B550-8D8BCBB2CE3BQ37351395-1367B95B-F4C6-4A59-ABEA-3C647BD48F69Q37559551-E578CFBF-7ACB-4371-ACEA-B3A21B45548CQ37600569-154CB8D1-62A8-4B52-876C-D3D23374CFB7Q37824123-7413E0B7-DBCE-4B27-8660-DBC785903E5BQ38111725-241E81CE-8AD7-409D-B90A-BFB79274D981Q38114865-850281B3-6F5C-4D0C-B78E-1A8215663E44Q38222614-CBF9F33C-AB2A-461F-B74F-97FA44AD4E9CQ38697830-105F721D-BB5C-496B-9D70-672D2B0873C3Q41710987-A7A27A51-F91C-4C63-9F3E-342E2A0DABEEQ42373933-BF50B1AF-BE72-4E1E-8D58-ED440C3AFBFEQ42713880-021DEFF4-67AE-4AB2-9B24-175387775BD2Q45941648-6BD10F2D-5F34-4CEB-9DD1-C89DEE0C430BQ46324293-35E7B512-484C-47BA-AFFD-B169B0911E78Q47069263-152C9349-8DEB-4039-9721-17EE02993D0FQ47158376-35522C0C-F559-4C68-8351-DDD4864DAD0FQ47711211-F0C1ABAB-C480-4AD3-973A-42E94095C833Q48793462-7C1C080B-A5EF-4280-A37A-599477AEF60CQ50332964-B68AA9C0-2F64-4614-AAF2-45C4C538756BQ51677782-07F8A66E-D27A-4321-AF4D-5016A9FA31E8Q53357013-CD973DCF-DC6A-4095-8967-2A24D275865FQ59126825-856D8DEE-344D-434E-A186-0F1DDE579FF7
P2860
Gene knockout and metabolome analysis of carnitine/organic cation transporter OCTN1.
description
2010 nî lūn-bûn
@nan
2010 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մարտին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Gene knockout and metabolome analysis of carnitine/organic cation transporter OCTN1.
@ast
Gene knockout and metabolome analysis of carnitine/organic cation transporter OCTN1.
@en
Gene knockout and metabolome analysis of carnitine/organic cation transporter OCTN1.
@nl
type
label
Gene knockout and metabolome analysis of carnitine/organic cation transporter OCTN1.
@ast
Gene knockout and metabolome analysis of carnitine/organic cation transporter OCTN1.
@en
Gene knockout and metabolome analysis of carnitine/organic cation transporter OCTN1.
@nl
prefLabel
Gene knockout and metabolome analysis of carnitine/organic cation transporter OCTN1.
@ast
Gene knockout and metabolome analysis of carnitine/organic cation transporter OCTN1.
@en
Gene knockout and metabolome analysis of carnitine/organic cation transporter OCTN1.
@nl
P2093
P1476
Gene knockout and metabolome analysis of carnitine/organic cation transporter OCTN1
@en
P2093
Akira Tsuji
Akiyoshi Hirayama
Daisuke Iwata
Kazushi Sugihara
Masahide Asano
Masahiro Sugimoto
Masaru Tomita
Morimasa Wada
Sayaka Kato
Shuichi Kaneko
P304
P356
10.1007/S11095-010-0076-Z
P577
2010-03-12T00:00:00Z