N-terminal transmembrane domain of SUR1 controls gating of Kir6.2 by modulating channel sensitivity to PIP2
about
Running out of time: the decline of channel activity and nucleotide activation in adenosine triphosphate-sensitive K-channelsEngineered Kir6.2 mutations that correct the trafficking defect of K(ATP) channels caused by specific SUR1 mutationsStabilization of Nucleotide Binding Domain Dimers Rescues ABCC6 Mutants Associated with Pseudoxanthoma Elasticum.A Kir6.2 pore mutation causes inactivation of ATP-sensitive potassium channels by disrupting PIP2-dependent gating.On potential interactions between non-selective cation channel TRPM4 and sulfonylurea receptor SUR1.Engineered interaction between SUR1 and Kir6.2 that enhances ATP sensitivity in KATP channels.Pharmacological rescue of trafficking-impaired ATP-sensitive potassium channels.The role of ATP-sensitive potassium channels in cellular function and protection in the cardiovascular systemModulation of Ionic Channels and Insulin Secretion by Drugs and Hormones in Pancreatic Beta Cells.Phosphatidylinositol 4,5-biphosphate (PIP2) modulates interaction of syntaxin-1A with sulfonylurea receptor 1 to regulate pancreatic β-cell ATP-sensitive potassium channels.ATP activates ATP-sensitive potassium channels composed of mutant sulfonylurea receptor 1 and Kir6.2 with diminished PIP2 sensitivityReinterpreting the action of ATP analogs on K(ATP) channels.Lipid signaling to membrane proteins: From second messengers to membrane domains and adapter-free endocytosis.Cryo-electron microscopy structures and progress toward a dynamic understanding of KATP channels.
P2860
Q26744692-EBA0FC78-AD46-4111-9852-F12436C80CE9Q28941209-BD818569-CD81-4684-B093-A926941F0672Q30396634-F0F60055-8449-4A33-8DCB-1B66B229E43EQ34735191-67E82946-95B2-40C9-B7A0-6129FA18AE85Q35842007-6268E406-48D8-46EA-B48F-45471E943CC0Q36130308-92EF05D7-AFEB-4C28-B53A-1AA4C7C644F0Q37409971-6F04EAEF-2853-40B8-AED5-5CACF9A3A0DAQ37418212-AC26E3D6-0543-4280-A0C2-A7DF64A08F83Q38902592-8C325203-9EB0-489B-BC2C-3540ACD54171Q39034153-A614113E-E34D-47DC-8733-3D4D270BB22CQ39430157-5AF572CB-7E2D-4D98-9C11-AC82414BBAB4Q41469020-8D1A2322-78BC-46BB-AB5B-6B9AC5607776Q48258000-92E96636-EDC8-4139-B745-D7A252A6EC16Q52312167-99D307EE-72D5-4D03-9D2A-1E10C17738DA
P2860
N-terminal transmembrane domain of SUR1 controls gating of Kir6.2 by modulating channel sensitivity to PIP2
description
2011 nî lūn-bûn
@nan
2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
N-terminal transmembrane domai ...... ng channel sensitivity to PIP2
@ast
N-terminal transmembrane domai ...... ng channel sensitivity to PIP2
@en
N-terminal transmembrane domai ...... ng channel sensitivity to PIP2
@nl
type
label
N-terminal transmembrane domai ...... ng channel sensitivity to PIP2
@ast
N-terminal transmembrane domai ...... ng channel sensitivity to PIP2
@en
N-terminal transmembrane domai ...... ng channel sensitivity to PIP2
@nl
prefLabel
N-terminal transmembrane domai ...... ng channel sensitivity to PIP2
@ast
N-terminal transmembrane domai ...... ng channel sensitivity to PIP2
@en
N-terminal transmembrane domai ...... ng channel sensitivity to PIP2
@nl
P2093
P2860
P356
P1476
N-terminal transmembrane domai ...... ng channel sensitivity to PIP2
@en
P2093
Cathrin E Bruederle
Emily B Pratt
Paul Tewson
Show-Ling Shyng
William R Skach
P2860
P304
P356
10.1085/JGP.201010557
P577
2011-02-14T00:00:00Z