Longitudinal noninvasive PET-based beta cell mass estimates in a spontaneous diabetes rat model. - Wikidata - wikimedia - TriplyDB

Longitudinal noninvasive PET-based beta cell mass estimates in a spontaneous diabetes rat model.

Longitudinal noninvasive PET-based beta cell mass estimates in a spontaneous diabetes rat model.

http://www.wikidata.org/entity/Q34619649

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Relationship between pancreatic vesicular monoamine transporter 2 (VMAT2) and insulin expression in human pancreas The development, past achievements, and future directions of brain PET Quantitative Impact of Plasma Clearance and Down-regulation on GLP-1 Receptor Molecular Imaging.Manganese-enhanced magnetic resonance imaging detects declining pancreatic β-cell mass in a cyclophosphamide-accelerated mouse model of type 1 diabetes.Noninvasive assessment of pancreatic beta-cell function in vivo with manganese-enhanced magnetic resonance imaging.Quantitative pancreatic β cell MRI using manganese-enhanced Look-Locker imaging and two-site water exchange analysis.Characterization of 5-(2- 18F-fluoroethoxy)-L-tryptophan for PET imaging of the pancreas.Generation of novel single-chain antibodies by phage-display technology to direct imaging agents highly selective to pancreatic beta- or alpha-cells in vivo.Imaging pancreas in healthy and diabetic rodent model using [18F]fallypride positron emission tomography/computed tomography.Arginine is preferred to glucagon for stimulation testing of β-cell function.New fluorescent substrate enables quantitative and high-throughput examination of vesicular monoamine transporter 2 (VMAT2)Noninvasive imaging of islet grafts using positron-emission tomography.Genome-wide DNA methylation analysis of human pancreatic islets from type 2 diabetic and non-diabetic donors identifies candidate genes that influence insulin secretion.Accurate measurement of pancreatic islet beta-cell mass using a second-generation fluorescent exendin-4 analog Multimodal image coregistration and inducible selective cell ablation to evaluate imaging ligands Synthesis and evaluation of [18F]exendin (9-39) as a potential biomarker to measure pancreatic β-cell mass.Multimodality imaging of β-cells in mouse models of type 1 and 2 diabetes Pharmacokinetics of [(18)F]fluoroalkyl derivatives of dihydrotetrabenazine in rat and monkey brain.Obstacles on the way to the clinical visualisation of beta cells: looking for the Aeneas of molecular imaging to navigate between Scylla and Charybdis.Diabetes imaging-quantitative assessment of islets of Langerhans distribution in murine pancreas using extended-focus optical coherence microscopy Imaging metabolic syndrome.A Novel Potential Positron Emission Tomography Imaging Agent for Vesicular Monoamine Transporter Type 2 Pancreatic magnetic resonance imaging after manganese injection distinguishes type 2 diabetic and normoglycemic patients.Radioiodinated naphthylalanine derivatives targeting pancreatic beta cells in normal and nonobese diabetic mice.Cross-sectional and Test-Retest Characterization of PET with [(18)F]FP-(+)-DTBZ for β Cell Mass Estimates in Diabetes.Vesicular monoamine transporter, type 2 (VMAT2) expression as it compares to insulin and pancreatic polypeptide in the head, body and tail of the human pancreas.Imaging of beta-cell mass and function The utility of [(11)C] dihydrotetrabenazine positron emission tomography scanning in assessing beta-cell performance after sleeve gastrectomy and duodenal-jejunal bypass American College of Endocrinology Pre-Diabetes Consensus Conference: part three Life and death of β cells in Type 1 diabetes: A comprehensive review.Pancreatic beta cell mass PET imaging and quantification with [11C]DTBZ and [18F]FP-(+)-DTBZ in rodent models of diabetes.In vivo imaging of endogenous pancreatic β-cell mass in healthy and type 1 diabetic subjects using 18F-fluoropropyl-dihydrotetrabenazine and PET.Real-time imaging of the pancreas during development of diabetes.Bioluminescence imaging in mouse models quantifies beta cell mass in the pancreas and after islet transplantation.PET studies of d-methamphetamine pharmacokinetics in primates: comparison with l-methamphetamine and ( --)-cocaine.Advances in beta-cell imaging Advances in molecular imaging of pancreatic beta cells Localization and expression of VMAT2 aross mammalian species: a translational guide for its visualization and targeting in health and disease.Evaluation of pancreatic VMAT2 binding with active and inactive enantiomers of 18F-FP-DTBZ in baboons Regenerative medicine for diabetes mellitus.

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Longitudinal noninvasive PET-based beta cell mass estimates in a spontaneous diabetes rat model.

http://www.wikidata.org/entity/Q34619649

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Journal of Clinical Investigation

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Anthony Raffo

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Antonella Maffei

http://www.w3.org/2001/XMLSchema#string

Chitra Saxena

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Fabiola Souza

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J John Mann

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Mark Hardy

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Michael Kilbourn

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Norman Simpson

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Paul E Harris

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Ronald Van Heertum

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P2860

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

Expression of the two isoforms of the vesicular monoamine transporter (VMAT1 and VMAT2) in the endocrine pancreas and pancreatic endocrine tumors

Norepinephrine and epinephrine-deficient mice are hyperinsulinemic and have lower blood glucose

Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes

Gene expression profiling in islet biology and diabetes research.

Pancreatic uptake of [2-(14)C]alloxan.

Developments in the prediction of type 1 diabetes mellitus, with special reference to insulin autoantibodies.

Chemical neuroanatomy of the vesicular amine transporters.

Endocrine pancreas plasticity under physiological and pathological conditions.

11C-DTBZ and 18F-FDG PET measures in differentiating dementias.

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1506-1513

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10.1172/JCI27645

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116

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