A novel small-molecule thienoquinolin urea transporter inhibitor acts as a potential diuretic.
about
Pathophysiology, Evaluation, and Management of Edema in Childhood Nephrotic SyndromeStructure of urea transportersEmerging Targets of Diuretic Therapy.Developing hypothetical inhibition mechanism of novel urea transporter B inhibitor.Generation and phenotypic analysis of mice lacking all urea transporters.Diuresis and reduced urinary osmolality in rats produced by small-molecule UT-A-selective urea transport inhibitors.Thienoquinolins exert diuresis by strongly inhibiting UT-A urea transporters.A small molecule screen identifies selective inhibitors of urea transporter UT-A.Small-molecule inhibitors of urea transporters.Dexamethasone attenuates LPS-induced changes in expression of urea transporter and aquaporin proteins, ameliorating brain endotoxemia in mice.Structure-activity analysis of thiourea analogs as inhibitors of UT-A and UT-B urea transporters.Discovery, synthesis and structure-activity analysis of symmetrical 2,7-disubstituted fluorenones as urea transporter inhibitors.Salt-sparing diuretic action of a water-soluble urea analog inhibitor of urea transporters UT-A and UT-B in ratsFunctional inhibition of urea transporter UT-B enhances endothelial-dependent vasodilatation and lowers blood pressure via L-arginine-endothelial nitric oxide synthase-nitric oxide pathway.Urea transporter proteins as targets for small-molecule diuretics.Urea channel inhibitors: a new functional class of aquareticsPhenylphthalazines as small-molecule inhibitors of urea transporter UT-B and their binding modelUrea transport and clinical potential of urearetics.The knockout of urea transporter-B improves the hemorheological properties of erythrocyte.Development and validation of an LC-MS/MS method for the determination of a novel thienoquinolin urea transporter inhibitor PU-48 in rat plasma and its application to a pharmacokinetic study.Tolvaptan promotes urinary excretion of sodium and urea: a retrospective cohort study.Nanomolar-Potency 1,2,4-Triazoloquinoxaline Inhibitors of the Kidney Urea Transporter UT-A1.Pharmacokinetics, Tissue Distribution and Excretion of a Novel Diuretic (PU-48) in Rats
P2860
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P2860
A novel small-molecule thienoquinolin urea transporter inhibitor acts as a potential diuretic.
description
2013 nî lūn-bûn
@nan
2013 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի մարտին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
A novel small-molecule thienoq ...... acts as a potential diuretic.
@ast
A novel small-molecule thienoq ...... acts as a potential diuretic.
@en
A novel small-molecule thienoq ...... acts as a potential diuretic.
@nl
type
label
A novel small-molecule thienoq ...... acts as a potential diuretic.
@ast
A novel small-molecule thienoq ...... acts as a potential diuretic.
@en
A novel small-molecule thienoq ...... acts as a potential diuretic.
@nl
prefLabel
A novel small-molecule thienoq ...... acts as a potential diuretic.
@ast
A novel small-molecule thienoq ...... acts as a potential diuretic.
@en
A novel small-molecule thienoq ...... acts as a potential diuretic.
@nl
P2093
P356
P1433
P1476
A novel small-molecule thienoq ...... acts as a potential diuretic.
@en
P2093
Baoxue Yang
Jihui Chen
Juanjuan Zhu
Tianluo Lei
Weiling Wang
Zixun Dong
P2888
P304
P356
10.1038/KI.2013.62
P407
P577
2013-03-13T00:00:00Z
P5875
P6179
1008481446