Loss of imprinting of the insulin-like growth factor II gene occurs by biallelic methylation in a core region of H19-associated CTCF-binding sites in colorectal cancer
about
Comprehensive molecular characterization of human colon and rectal cancerMutations in the IGF-II pathway that confer resistance to lytic reovirus infectionA screen for germline mutations in the gene encoding CCCTC-binding factor (CTCF) in familial non-BRCA1/BRCA2 breast cancerDNA modifications: function and applications in normal and disease StatesNoncoding RNAs in Tumor Epithelial-to-Mesenchymal TransitionLong Noncoding RNA in Digestive Tract Cancers: Function, Mechanism, and Potential BiomarkerMethylation-mediated silencing of TMS1/ASC is accompanied by histone hypoacetylation and CpG island-localized changes in chromatin architectureMethylation mattersGender-specific methylation differences in relation to prenatal exposure to cigarette smokeEpigenetic features of human mesenchymal stem cells determine their permissiveness for induction of relevant transcriptional changes by SYT-SSX1.Impact of the genome on the epigenome is manifested in DNA methylation patterns of imprinted regions in monozygotic and dizygotic twinsThe aberrant asynchronous replication - characterizing lymphocytes of cancer patients - is erased following stem cell transplantationLoss of IGF2 imprinting is associated with abrogation of long-range intrachromosomal interactions in human cancer cells.Insulin-like growth factor pathway genetic polymorphisms, circulating IGF1 and IGFBP3, and prostate cancer survival.Validation of methylation biomarkers that distinguish normal colon mucosa of cancer patients from normal colon mucosa of patients without cancer.Methylation variation at IGF2 differentially methylated regions and maternal folic acid use before and during pregnancy.Microdeletion of target sites for insulator protein CTCF in a chromosome 11p15 imprinting center in Beckwith-Wiedemann syndrome and Wilms' tumor.Mechanisms by which IGF-I may promote cancerErythrocyte folate concentrations, CpG methylation at genomically imprinted domains, and birth weight in a multiethnic newborn cohortFrom genotype to functional phenotype: unraveling the metabolomic features of colorectal cancer.Hypomethylation of the IGF2 DMR in colorectal tumors, detected by bisulfite pyrosequencing, is associated with poor prognosisDistinct allelic expression patterns of imprinted IGF2 in adenocarcinoma and squamous cell carcinoma of the lung.Selective methylation of CpGs at regulatory binding sites controls NNAT expression in Wilms tumors.Colonic mucosal DNA methylation, immune response, and microbiome patterns in Toll-like receptor 2-knockout miceInvolvement of long non-coding RNA in colorectal cancer: From benchtop to bedside (Review)Non-random, individual-specific methylation profiles are present at the sixth CTCF binding site in the human H19/IGF2 imprinting control regionEffect of maternal and post-weaning folate supply on gene-specific DNA methylation in the small intestine of weaning and adult apc and wild type mice.Loss of imprinting and marked gene elevation are 2 forms of aberrant IGF2 expression in colorectal cancer.Epigenetic differences in normal colon mucosa of cancer patients suggest altered dietary metabolic pathways.Association of cord blood methylation fractions at imprinted insulin-like growth factor 2 (IGF2), plasma IGF2, and birth weightDNA hypermethylation appears early and shows increased frequency with dysplasia in Lynch syndrome-associated colorectal adenomas and carcinomas.Pax6 regulation in retinal cells by CCCTC binding factor.Cancer epigenetics takes center stage.Predicting lncRNA-disease associations and constructing lncRNA functional similarity network based on the information of miRNAInsulin-like growth factor 2/H19 methylation at birth and risk of overweight and obesity in childrenDietary factors, genetic and epigenetic influences in colorectal cancer.MSH6 missense mutations are often associated with no or low cancer susceptibilityClassification of colorectal cancer based on correlation of clinical, morphological and molecular features.Colorectal cancer epigenetics: the role of environmental factors and the search for molecular biomarkers.Lead Exposure during Early Human Development and DNA Methylation of Imprinted Gene Regulatory Elements in Adulthood.
P2860
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P2860
Loss of imprinting of the insulin-like growth factor II gene occurs by biallelic methylation in a core region of H19-associated CTCF-binding sites in colorectal cancer
description
2000 nî lūn-bûn
@nan
2000 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Loss of imprinting of the insu ...... ing sites in colorectal cancer
@ast
Loss of imprinting of the insu ...... ing sites in colorectal cancer
@en
Loss of imprinting of the insu ...... ing sites in colorectal cancer
@nl
type
label
Loss of imprinting of the insu ...... ing sites in colorectal cancer
@ast
Loss of imprinting of the insu ...... ing sites in colorectal cancer
@en
Loss of imprinting of the insu ...... ing sites in colorectal cancer
@nl
prefLabel
Loss of imprinting of the insu ...... ing sites in colorectal cancer
@ast
Loss of imprinting of the insu ...... ing sites in colorectal cancer
@en
Loss of imprinting of the insu ...... ing sites in colorectal cancer
@nl
P2093
P2860
P356
P1476
Loss of imprinting of the insu ...... ing sites in colorectal cancer
@en
P2093
A de La Chapelle
H Nakagawa
P Peltomaki
R B Chadwick
Y Nakamura
P2860
P304
P356
10.1073/PNAS.011528698
P407
P577
2000-12-19T00:00:00Z