Discovery of a novel small molecule inhibitor targeting the frataxin/ubiquitin interaction via structure-based virtual screening and bioassays.

Discovery of a novel small molecule inhibitor targeting the frataxin/ubiquitin interaction via structure-based virtual screening and bioassays.

Item
http://www.wikidata.org/entity/Q34626568
Human Cystathionine-β-Synthase Phosphorylation on Serine227 Modulates Hydrogen Sulfide Production in Human UrotheliumState-of-the-art strategies for targeting protein-protein interactions by small-molecule inhibitors.Discovery of new small molecules inhibiting 67 kDa laminin receptor interaction with laminin and cancer cell invasionPerturbation of cellular proteostasis networks identifies pathways that modulate precursor and intermediate but not mature levels of frataxinRegulatory role of rpL3 in cell response to nucleolar stress induced by Act D in tumor cells lacking functional p53Role of uL3 in Multidrug Resistance in p53-Mutated Lung Cancer Cells.Screening for E3-ubiquitin ligase inhibitors: challenges and opportunities.In silico studies in drug research against neurodegenerative diseases.Human rpL3 plays a crucial role in cell response to nucleolar stress induced by 5-FU and L-OHP.Ribosomal Proteins Control or Bypass p53 during Nucleolar Stress.Identification of potential CCR5 inhibitors through pharmacophore-based virtual screening, molecular dynamics simulation and binding free energy analysis.Structural basis for PPAR partial or full activation revealed by a novel ligand binding mode.Synthesis of Benzyl Amines via Copper-Catalyzed Enantioselective Aza-Friedel-Crafts Addition of Phenols to N-Sulfonyl Aldimines.
P2860

Discovery of a novel small molecule inhibitor targeting the frataxin/ubiquitin interaction via structure-based virtual screening and bioassays.

Item
http://www.wikidata.org/entity/Q34626568
description
2013 nî lūn-bûn
@nan
2013 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի մարտին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Discovery of a novel small mol ...... rtual screening and bioassays.
@ast
Discovery of a novel small mol ...... rtual screening and bioassays.
@en
Discovery of a novel small mol ...... rtual screening and bioassays.
@nl
type
label
Discovery of a novel small mol ...... rtual screening and bioassays.
@ast
Discovery of a novel small mol ...... rtual screening and bioassays.
@en
Discovery of a novel small mol ...... rtual screening and bioassays.
@nl
prefLabel
Discovery of a novel small mol ...... rtual screening and bioassays.
@ast
Discovery of a novel small mol ...... rtual screening and bioassays.
@en
Discovery of a novel small mol ...... rtual screening and bioassays.
@nl
P1433
P1476
P2093
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P356
P1433
P1476
Discovery of a novel small mol ...... rtual screening and bioassays.
@en
P2093
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698