Direct regulation of complex I by mitochondrial MEF2D is disrupted in a mouse model of Parkinson disease and in human patients.
about
Tyrosine phosphorylation of mitochondrial pyruvate dehydrogenase kinase 1 is important for cancer metabolismThe import of the transcription factor STAT3 into mitochondria depends on GRIM-19, a component of the electron transport chainChaperone-Mediated Autophagy and Mitochondrial Homeostasis in Parkinson's DiseaseInteractions between mitochondria and the transcription factor myocyte enhancer factor 2 (MEF2) regulate neuronal structural and functional plasticity and metaplasticityReactive Oxygen Species: Physiological and Physiopathological Effects on Synaptic PlasticityDysregulation of autophagy and mitochondrial function in Parkinson's diseaseDifferential Protein Distribution between the Nucleus and Mitochondria: Implications in AgingDynamic self-guiding analysis of Alzheimer's disease.Oxidation of survival factor MEF2D in neuronal death and Parkinson's diseaseA mitochondrial etiology of Alzheimer and Parkinson diseaseMito-nuclear co-evolution: the positive and negative sides of functional ancient mutationsTranscriptomic analysis of brown adipose tissue across the physiological extremes of natural hibernationTranscription factor myocyte enhancer factor 2D regulates interleukin-10 production in microglia to protect neuronal cells from inflammation-induced death.The ARL2 GTPase is required for mitochondrial morphology, motility, and maintenance of ATP levels.Calpain-mediated degradation of myocyte enhancer factor 2D contributes to excitotoxicity by activation of extrasynaptic N-methyl-D-aspartate receptorsDifferential Expression of Genes that Control Respiration Contribute to Thermal Adaptation in Redband Trout (Oncorhynchus mykiss gairdneri).Potent Protection Against MPP(+)-Induced Neurotoxicity via Activating Transcription Factor MEF2D by a Novel Derivative of Naturally Occurring Danshensu/Tetramethylpyrazine.Ancient Out-of-Africa Mitochondrial DNA Variants Associate with Distinct Mitochondrial Gene Expression Patterns.Activation of transcription factor MEF2D by bis(3)-cognitin protects dopaminergic neurons and ameliorates Parkinsonian motor defects.Perturbation of transcription factor Nur77 expression mediated by myocyte enhancer factor 2D (MEF2D) regulates dopaminergic neuron loss in response to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).Essential control of mitochondrial morphology and function by chaperone-mediated autophagy through degradation of PARK7Higher order signaling: ARL2 as regulator of both mitochondrial fusion and microtubule dynamics allows integration of 2 essential cell functions.Evidence for site-specific occupancy of the mitochondrial genome by nuclear transcription factors.The little big genome: the organization of mitochondrial DNA.ATM-dependent phosphorylation of MEF2D promotes neuronal survival after DNA damage.Mitochondrial PKM2 regulates oxidative stress-induced apoptosis by stabilizing Bcl2.Multi-tasking: nuclear transcription factors with novel roles in the mitochondria.Engrailed signaling in axon guidance and neuron survival.The MEF2 family and the brain: from molecules to memory.Mitochondria in health, aging and diseases: the epigenetic perspective.An unexpected role for the transcriptional coactivator isoform NT-PGC-1α in the regulation of mitochondrial respiration in brown adipocytes.Molecular changes in the postmortem parkinsonian brain.Nuclear Transcription Factors in the Mitochondria: A New Paradigm in Fine-Tuning Mitochondrial Metabolism.Imaging and spectroscopic approaches to probe brain energy metabolism dysregulation in neurodegenerative diseases.Experimental support that natural selection has shaped the latitudinal distribution of mitochondrial haplotypes in Australian Drosophila melanogaster.Destabilization of survival factor MEF2D mRNA by neurotoxin in models of Parkinson's disease.Role of Chaperone-Mediated Autophagy Dysfunctions in the Pathogenesis of Parkinson's Disease.Rotenone upregulates alpha-synuclein and myocyte enhancer factor 2D independently from lysosomal degradation inhibition.Nuclear but not mitochondrial-encoded oxidative phosphorylation genes are altered in aging, mild cognitive impairment, and Alzheimer's disease.Neurotoxin-induced selective ubiquitination and regulation of MEF2A isoform in neuronal stress response.
P2860
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P2860
Direct regulation of complex I by mitochondrial MEF2D is disrupted in a mouse model of Parkinson disease and in human patients.
description
2011 nî lūn-bûn
@nan
2011 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մարտին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Direct regulation of complex I ...... isease and in human patients.
@ast
Direct regulation of complex I ...... isease and in human patients.
@en
Direct regulation of complex I ...... isease and in human patients.
@nl
type
label
Direct regulation of complex I ...... isease and in human patients.
@ast
Direct regulation of complex I ...... isease and in human patients.
@en
Direct regulation of complex I ...... isease and in human patients.
@nl
prefLabel
Direct regulation of complex I ...... isease and in human patients.
@ast
Direct regulation of complex I ...... isease and in human patients.
@en
Direct regulation of complex I ...... isease and in human patients.
@nl
P2093
P2860
P356
P1476
Direct regulation of complex I ...... isease and in human patients.
@en
P2093
Claudia Testa
Gary Miller
Kennie Shepherd
Yoland Smith
P2860
P304
P356
10.1172/JCI43871
P407
P577
2011-03-01T00:00:00Z