Molecular kinetics. Ras activation by SOS: allosteric regulation by altered fluctuation dynamics. - Wikidata - wikimedia - TriplyDB

Molecular kinetics. Ras activation by SOS: allosteric regulation by altered fluctuation dynamics.

Molecular kinetics. Ras activation by SOS: allosteric regulation by altered fluctuation dynamics.

http://www.wikidata.org/entity/Q34631440

about

Current approaches to studying membrane organization Seeing and believing: recent advances in imaging cell-cell interactions Shedding light on protein folding, structural and functional dynamics by single molecule studies Keep on moving: discovering and perturbing the conformational dynamics of enzymes The dynamical nature of enzymatic catalysis.Phosphotyrosine-mediated LAT assembly on membranes drives kinetic bifurcation in recruitment dynamics of the Ras activator SOS.One-way membrane trafficking of SOS in receptor-triggered Ras activation.Mechanism of SOS PR-domain autoinhibition revealed by single-molecule assays on native protein from lysate.Inhibitors of Ras-SOS Interactions.Stochastic focusing coupled with negative feedback enables robust regulation in biochemical reaction networks The Structural Basis of Oncogenic Mutations G12, G13 and Q61 in Small GTPase K-Ras4B.Plasma membrane regulates Ras signaling networks.Direct observation of proton pumping by a eukaryotic P-type ATPase.Supported lipid bilayers as dynamic platforms for tethered particles.Supported Lipid Bilayers for the Generation of Dynamic Cell-Material Interfaces.Deconstruction of the Ras switching cycle through saturation mutagenesis.Drugging Ras GTPase: a comprehensive mechanistic and signaling structural view.Single-Molecule Sensors: Challenges and Opportunities for Quantitative Analysis.Membrane orientation dynamics of lipid-modified small GTPases.Dynamic studies of H-Ras•GTPγS interactions with nucleotide exchange factor Sos reveal a transient ternary complex formation in solution.Monitoring the Waiting Time Sequence of Single Ras GTPase Activation Events Using Liposome Functionalized Zero-Mode Waveguides.Monitoring Ras Interactions with the Nucleotide Exchange Factor Son of Sevenless (Sos) Using Site-specific NMR Reporter Signals and Intrinsic Fluorescence.Covalent Ras Dimerization on Membrane Surfaces through Photosensitized Oxidation.Transitions in genetic toggle switches driven by dynamic disorder in rate coefficients.Switching of the positive feedback for RAS activation by a concerted function of SOS membrane association domains.The invariances of power law size distributions.Allosteric Modulation of Grb2 Recruitment to the Intrinsically Disordered Scaffold Protein, LAT, by Remote Site Phosphorylation.K-Ras4B Remains Monomeric on Membranes over a Wide Range of Surface Densities and Lipid Compositions.Dynamic disorder in simple enzymatic reactions induces stochastic amplification of substrate.Detection of Correlated Protein Backbone and Side-Chain Angle Fluctuations.Kinetics of PTEN-mediated PI(3,4,5)P3 hydrolysis on solid supported membranes.Rhythmicity and waves in the cortex of single cells.New insights into RAS biology reinvigorate interest in mathematical modeling of RAS signaling.

P2860

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P2860

Molecular kinetics. Ras activation by SOS: allosteric regulation by altered fluctuation dynamics.

http://www.wikidata.org/entity/Q34631440

description

2014 nî lūn-bûn

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2014 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի հուլիսին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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name

Molecular kinetics. Ras activa ...... altered fluctuation dynamics.

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Molecular kinetics. Ras activa ...... altered fluctuation dynamics.

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Molecular kinetics. Ras activa ...... altered fluctuation dynamics.

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Molecular kinetics. Ras activa ...... altered fluctuation dynamics.

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Molecular kinetics. Ras activa ...... altered fluctuation dynamics.

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Molecular kinetics. Ras activa ...... altered fluctuation dynamics.

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Molecular kinetics. Ras activa ...... altered fluctuation dynamics.

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Molecular kinetics. Ras activa ...... altered fluctuation dynamics.

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Molecular kinetics. Ras activa ...... altered fluctuation dynamics.

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Molecular kinetics. Ras activa ...... altered fluctuation dynamics.

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Arup K Chakraborty

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Cheng-Han Yu

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Christopher Rhodes

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Jay T Groves

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Jeff Iwig

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Jodi Gureasko

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John Kuriyan

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Lars Iversen

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Peter Thill

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Rebecca S Petit

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P2860

Structural evidence for feedback activation by Ras.GTP of the Ras-specific nucleotide exchange factor SOS

Structural analysis of autoinhibition in the Ras activator Son of sevenless

Unusual interplay of two types of Ras activators, RasGRP and SOS, establishes sensitive and robust Ras activation in lymphocytes

Regulation of small GTPases by GEFs, GAPs, and GDIs

Observation of a Power-Law Memory Kernel for Fluctuations within a Single Protein Molecule

Role of the histone domain in the autoinhibition and activation of the Ras activator Son of Sevenless

Single-molecule enzymatic dynamics

Ever-fluctuating single enzyme molecules: Michaelis-Menten equation revisited

GEFs and GAPs: critical elements in the control of small G proteins

Ras plasma membrane signalling platforms

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Sune M Christensen

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