Oral resiquimod in chronic HCV infection: safety and efficacy in 2 placebo-controlled, double-blind phase IIa studies.
about
Targeting toll-like receptors: promising therapeutic strategies for the management of sepsis-associated pathology and infectious diseasesSkin TLR7 triggering promotes accumulation of respiratory dendritic cells and natural killer cellsHepatitis C and Innate Immunity: Recent AdvancesHepatitis C Virus Is a Weak Inducer of Interferon Alpha in Plasmacytoid Dendritic Cells in Comparison with Influenza and Human Herpesvirus Type-1High throughput screening for small molecule enhancers of the interferon signaling pathway to drive next-generation antiviral drug discoveryToll-like receptor 7 agonists: chemical feature based pharmacophore identification and molecular docking studiesTickling the TLR7 to cure viral hepatitis.The therapeutic potential of Toll-like receptor 7 stimulation in asthma.Adjuvant-carrying synthetic vaccine particles augment the immune response to encapsulated antigen and exhibit strong local immune activation without inducing systemic cytokine release.R-848 triggers the expression of TLR7/8 and suppresses HIV replication in monocytesA phase II dose-ranging study of topical resiquimod to treat actinic keratosis.The pharmacokinetics of Toll-like receptor agonists and the impact on the immune system.Use of modelling and simulation techniques to support decision making on the progression of PF-04878691, a TLR7 agonist being developed for hepatitis CUpping the antedrug: is a novel anti-inflammatory Toll-like receptor 7 agonist also a bronchodilator?Biological characterization of a novel class of toll-like receptor 7 agonists designed to have reduced systemic activityTrial Watch: Experimental Toll-like receptor agonists for cancer therapyTolerability in man following inhalation dosing of the selective TLR7 agonist, AZD8848.IFN-α subtypes: distinct biological activities in anti-viral therapy.GS-9620, an oral agonist of Toll-like receptor-7, induces prolonged suppression of hepatitis B virus in chronically infected chimpanzees.Toll-like receptor 7 affects the pathogenesis of non-alcoholic fatty liver disease.TLR-7 activation enhances IL-22-mediated colonization resistance against vancomycin-resistant enterococcus.Evaluation of mucosal adjuvants and immunization routes for the induction of systemic and mucosal humoral immune responses in macaques.Liposomal resiquimod for the treatment of Leishmania donovani infection.Therapeutic targeting of Toll-like receptors for infectious and inflammatory diseases and cancer.HCV drug discovery aimed at viral eradication.New NS5B polymerase inhibitors for hepatitis C.Toll-like receptor modulators: a patent review (2006-2010).The type I interferon response during viral infections: a "SWOT" analysis.Prophylactic and therapeutic implications of toll-like receptor ligands.Preclinical development of TLR ligands as drugs for the treatment of chronic viral infections.Resiquimod, a topical drug for viral skin lesions and skin cancer.Adjuvant immunotherapies as a novel approach to bacterial infections.Innate immunity in systemic sclerosis pathogenesis.Monocyte/macrophage inflammatory response pathways to combat Francisella infection: possible therapeutic targets?Promising Role of Toll-Like Receptor 8 Agonist in Concert with Prostratin for Activation of Silent HIV.An Enzyme-Directed Imidazoquinoline for Cancer Immunotherapy.Strategies for designing synthetic immune agonists.Cognitive impairment in relation to depression, anxiety and virological response in hepatitis C patients in Egypt.Anti-tumor Activity of Toll-Like Receptor 7 Agonists.TLR7/8 ligand, R-848, inhibits IgE synthesis by acting directly on B lymphocytes.
P2860
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P2860
Oral resiquimod in chronic HCV infection: safety and efficacy in 2 placebo-controlled, double-blind phase IIa studies.
description
2007 nî lūn-bûn
@nan
2007 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Oral resiquimod in chronic HCV ...... ouble-blind phase IIa studies.
@ast
Oral resiquimod in chronic HCV ...... ouble-blind phase IIa studies.
@en
Oral resiquimod in chronic HCV ...... ouble-blind phase IIa studies.
@nl
type
label
Oral resiquimod in chronic HCV ...... ouble-blind phase IIa studies.
@ast
Oral resiquimod in chronic HCV ...... ouble-blind phase IIa studies.
@en
Oral resiquimod in chronic HCV ...... ouble-blind phase IIa studies.
@nl
prefLabel
Oral resiquimod in chronic HCV ...... ouble-blind phase IIa studies.
@ast
Oral resiquimod in chronic HCV ...... ouble-blind phase IIa studies.
@en
Oral resiquimod in chronic HCV ...... ouble-blind phase IIa studies.
@nl
P2093
P1476
Oral resiquimod in chronic HCV ...... ouble-blind phase IIa studies.
@en
P2093
Dominque Guyader
Heather Patton
John G McHutchison
Myron J Tong
Paul J Pockros
Terry Wright
Tze-Chiang Meng
P304
P356
10.1016/J.JHEP.2007.02.025
P577
2007-05-04T00:00:00Z