T cells expressing the transcription factor PLZF regulate the development of memory-like CD8+ T cells
about
Tec family kinases Itk and Rlk / Txk in T lymphocytes: cross-regulation of cytokine production and T-cell fatesCytokine-induced cytokine production by conventional and innate lymphoid cellsTranscriptional regulation of the NKT cell lineageLin28b reprograms adult bone marrow hematopoietic progenitors to mediate fetal-like lymphopoiesisA spatially-organized multicellular innate immune response in lymph nodes limits systemic pathogen spread.Conserved and divergent aspects of human T-cell development and migration in humanized miceT-Bet independent development of IFNγ secreting natural T helper 1 cell population in the absence of Itk.Dendritic cell-MHC class II and Itk regulate functional development of regulatory innate memory CD4+ T cells in bone marrow transplantation.Cutting edge: innate memory CD8+ T cells are distinct from homeostatic expanded CD8+ T cells and rapidly respond to primary antigenic stimuli.ITK tunes IL-4-induced development of innate memory CD8+ T cells in a γδ T and invariant NKT cell-independent manner.Signal-transducing adaptor protein-2 promotes generation of functional long-term memory CD8+ T cells by preventing terminal effector differentiation.Innate PLZF+CD4+ αβ T cells develop and expand in the absence of Itk.Development of innate CD4+ and CD8+ T cells in Itk-deficient mice is regulated by distinct pathwaysAltered development of NKT cells, γδ T cells, CD8 T cells and NK cells in a PLZF deficient patient.Memory phenotype CD4 T cells undergoing rapid, nonburst-like, cytokine-driven proliferation can be distinguished from antigen-experienced memory cellsAging of the T cell compartment in mice and humans: from no naive expectations to foggy memories.Cutting edge: Lymphoproliferation caused by Fas deficiency is dependent on the transcription factor eomesodermin.ID'ing innate and innate-like lymphoid cellsInterleukin-4 regulates eomesodermin in CD8+ T cell development and differentiation.Alternative memory in the CD8 T cell lineageTranscriptional control of invariant NKT cell development.HDAC1 controls CD8+ T cell homeostasis and antiviral response.Kruppel-like factor 2 is required for trafficking but not quiescence in postactivated T cellsKrüppel-like factor 2 (KLF2) regulates B-cell reactivity, subset differentiation, and trafficking molecule expressionAntigen-inexperienced memory CD8+ T cells: where they come from and why we need them.Foxo: in command of T lymphocyte homeostasis and tolerance.The tyrosine kinase Itk suppresses CD8+ memory T cell development in response to bacterial infection.KLF13 sustains thymic memory-like CD8(+) T cells in BALB/c mice by regulating IL-4-generating invariant natural killer T cells.Jarid2 is induced by TCR signalling and controls iNKT cell maturation.The signaling symphony: T cell receptor tunes cytokine-mediated T cell differentiationPositive selecting cell type determines the phenotype of MHC class Ib-restricted CD8+ T cells.Cytokine signals through PI-3 kinase pathway modulate Th17 cytokine production by CCR6+ human memory T cells.MHC class II-restricted interaction between thymocytes plays an essential role in the production of innate CD8+ T cells.Let-7 microRNAs target the lineage-specific transcription factor PLZF to regulate terminal NKT cell differentiation and effector function.A locus on mouse chromosome 13 inversely regulates CD1d expression and the development of invariant natural killer T-cells.The transcription factor KLF2 restrains CD4⁺ T follicular helper cell differentiation.The transcription factor lymphoid enhancer factor 1 controls invariant natural killer T cell expansion and Th2-type effector differentiation.Loss of PLZF expression in prostate cancer by immunohistochemistry correlates with tumor aggressiveness and metastasis.Type I interferons regulate eomesodermin expression and the development of unconventional memory CD8(+) T cells.IL-4 acts as a potent stimulator of IFN-γ expression in CD8+ T cells through STAT6-dependent and independent induction of Eomesodermin and T-bet.
P2860
Q24610908-144B4E57-559A-417E-9E84-28A16D549510Q27007655-10C765F8-313C-45AF-90E5-CA40AC549BC8Q27012749-DD0FDDCF-2A78-4964-ADE1-2247EBBC4F7FQ28260255-91E84025-45B9-47D7-B7C0-A58301E46D29Q30528971-F485B84B-F238-433B-8C37-391BAE00D7F5Q30664978-D1B1C40D-C45E-4558-8FB0-206D8F952121Q33559914-2B768FAE-BEE9-4621-8D5F-2E19353D7F51Q33660085-33E02CBB-B1C6-4D55-B074-451EBD59F71AQ33660129-ACA41049-3140-410C-9F65-7D3340B9AF18Q33750857-A6415BDD-A7C1-47CD-9550-632CD3DE7B9BQ33761541-73894EA7-2D77-449C-BA7C-EAC685036DFEQ33852292-083FD347-F25D-489B-9F08-A5636D1FF143Q33966006-7A17B1A1-CF8E-4E7B-88D0-FE699CFB4B34Q34019039-452B5C3D-8CD2-464E-8F1C-6E1D5171B2FDQ34055175-0E66D455-DF98-4633-B705-925BBF499034Q34147526-A7427DB4-8640-4E3A-9021-C959457D9318Q34149729-BB42B8B1-06EB-4A75-B3FF-B1837BC306F9Q34157945-1607EA44-8A43-4F2C-B58B-83BC16DA0F1BQ34160201-509ACBF7-59F9-4A11-B182-3B0EE6E77E6DQ34162209-62D96DAC-4711-4032-9CB1-16460E51F977Q34248566-B6C9F437-CB17-473F-BFDB-90E94BD38B72Q34379613-C74473A1-BB63-461A-881B-8CD5EDD42B79Q34472224-F116335E-4FE7-40AA-B540-18D20614ACB3Q34490471-7B0DB94B-67C6-443D-B7EC-3FB9F5D15EF8Q34556329-4DE4BEFF-013E-4F07-BE72-7D6D606296C2Q34645402-4DEDC6FA-B754-427E-B431-5347D980A91FQ34865003-7507187B-A912-4A66-8A98-34473D79BCE6Q34973712-0AABD103-FF63-4C7A-B569-0C79DFEE1E37Q35039298-83CB8E10-0DE0-4BAF-B830-7CCB8E38BCF9Q35115481-E8DFEB7D-41B5-4461-B14F-829C921F7F1EQ35164668-DD48F0E6-02AA-40D8-951D-4CABE8AD0B38Q35208359-7927B96E-3492-4DA0-8A92-287255ED0060Q35334560-82573108-A1DC-46BD-8781-2DEEF9DCED32Q35528627-7DE103E5-A776-4168-9037-C1784E607820Q35537082-7565BF48-D2FA-4FA1-967B-622CA53B5E4EQ35537706-8DB0230B-7575-4097-81B5-EBCB43C44D98Q35568453-EFF9FF17-0C5F-402C-A3EF-A2370F2B8625Q35586422-ECD4E0F9-BCAA-4EF5-87E9-69FEAB2E7848Q35608970-3079F23E-EC15-4B7B-9098-856BC63E6743Q35634137-28D2A263-55E0-4329-8BE3-24EC90B2419E
P2860
T cells expressing the transcription factor PLZF regulate the development of memory-like CD8+ T cells
description
2010 nî lūn-bûn
@nan
2010 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
T cells expressing the transcr ...... nt of memory-like CD8+ T cells
@ast
T cells expressing the transcr ...... nt of memory-like CD8+ T cells
@en
T cells expressing the transcr ...... nt of memory-like CD8+ T cells
@nl
type
label
T cells expressing the transcr ...... nt of memory-like CD8+ T cells
@ast
T cells expressing the transcr ...... nt of memory-like CD8+ T cells
@en
T cells expressing the transcr ...... nt of memory-like CD8+ T cells
@nl
prefLabel
T cells expressing the transcr ...... nt of memory-like CD8+ T cells
@ast
T cells expressing the transcr ...... nt of memory-like CD8+ T cells
@en
T cells expressing the transcr ...... nt of memory-like CD8+ T cells
@nl
P2860
P356
P1433
P1476
T cells expressing the transcr ...... nt of memory-like CD8+ T cells
@en
P2093
Michael A Weinreich
Oludare A Odumade
P2860
P2888
P304
P356
10.1038/NI.1898
P407
P577
2010-07-04T00:00:00Z
P5875
P6179
1020415279