Palmitoylethanolamide exerts neuroprotective effects in mixed neuroglial cultures and organotypic hippocampal slices via peroxisome proliferator-activated receptor-α - Wikidata - wikimedia - TriplyDB

Palmitoylethanolamide exerts neuroprotective effects in mixed neuroglial cultures and organotypic hippocampal slices via peroxisome proliferator-activated receptor-α

Palmitoylethanolamide exerts neuroprotective effects in mixed neuroglial cultures and organotypic hippocampal slices via peroxisome proliferator-activated receptor-α

http://www.wikidata.org/entity/Q34636570

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Treatment of chronic regional pain syndrome type 1 with palmitoylethanolamide and topical ketamine cream: modulation of nonneuronal cells.Glial Modulation by N-acylethanolamides in Brain Injury and Neurodegeneration Does neuroinflammation turn on the flame in Alzheimer's disease? Focus on astrocytes Organotypic brain slice cultures: A review A fatty gut feeling Perinatal asphyxia results in altered expression of the hippocampal acylethanolamide/endocannabinoid signaling system associated to memory impairments in postweaned rats.Regulation of Ketone Body Metabolism and the Role of PPARα Effects of Intermittent Alcohol Exposure on Emotion and Cognition: A Potential Role for the Endogenous Cannabinoid System and Neuroinflammation.The pharmacology of palmitoylethanolamide and first data on the therapeutic efficacy of some of its new formulations.PPAR-alpha and PPAR-beta expression changes in the hippocampus of rats undergoing global cerebral ischemia/reperfusion due to PPAR-gamma status Localization of peroxisome proliferator-activated receptor alpha (PPARα) and N-acyl phosphatidylethanolamine phospholipase D (NAPE-PLD) in cells expressing the Ca(2+)-binding proteins calbindin, calretinin, and parvalbumin in the adult rat hippocamp Palmitoylethanolamide inhibits glutamate release in rat cerebrocortical nerve terminals Oxidative Stress during the Progression of β-Amyloid Pathology in the Neocortex of the Tg2576 Mouse Model of Alzheimer's Disease.Mast cell-glia axis in neuroinflammation and therapeutic potential of the anandamide congener palmitoylethanolamide.Environmental Enrichment, Age, and PPARα Interact to Regulate Proliferation in Neurogenic Niches.Acetylcholine receptors from human muscle as pharmacological targets for ALS therapy.Evolution in pharmacologic thinking around the natural analgesic palmitoylethanolamide: from nonspecific resistance to PPAR-α agonist and effective nutraceutical.Brain levels of prostaglandins, endocannabinoids, and related lipids are affected by mating strategies.Glia and mast cells as targets for palmitoylethanolamide, an anti-inflammatory and neuroprotective lipid mediator.Mast cells, glia and neuroinflammation: partners in crime?Role of astrocytes in major neurological disorders: the evidence and implications.An update on PPAR activation by cannabinoids.PPARα activation attenuates amyloid-β-dependent neurodegeneration by modulating Endo G and AIF translocation.Palmitoylethanolamide is a disease-modifying agent in peripheral neuropathy: pain relief and neuroprotection share a PPAR-alpha-mediated mechanism.Sirtuin modulators control reactive gliosis in an in vitro model of Alzheimer's disease.Differential Effects of Palmitoylethanolamide against Amyloid-β Induced Toxicity in Cortical Neuronal and Astrocytic Primary Cultures from Wild-Type and 3xTg-AD Mice.Palmitoylethanolamide controls reactive gliosis and exerts neuroprotective functions in a rat model of Alzheimer's disease.Palmitoylethanolamide Blunts Amyloid-β42-Induced Astrocyte Activation and Improves Neuronal Survival in Primary Mouse Cortical Astrocyte-Neuron Co-Cultures.Ultramicronized palmitoylethanolamide rescues learning and memory impairments in a triple transgenic mouse model of Alzheimer's disease by exerting anti-inflammatory and neuroprotective effects.Multiple mechanisms of dimethyl fumarate in amyloid β-induced neurotoxicity in human neuronal cells.Palmitoylethanolamide Ameliorates Hippocampal Damage and Behavioral Dysfunction After Perinatal Asphyxia in the Immature Rat Brain.Palmitoylethanolamide Dampens Reactive Astrogliosis and Improves Neuronal Trophic Support in a Triple Transgenic Model of Alzheimer's Disease: In Vitro and In Vivo Evidence.A Pharmacological Rationale to Reduce the Incidence of Opioid Induced Tolerance and Hyperalgesia: A Review.

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Palmitoylethanolamide exerts neuroprotective effects in mixed neuroglial cultures and organotypic hippocampal slices via peroxisome proliferator-activated receptor-α

http://www.wikidata.org/entity/Q34636570

description

2012 nî lūn-bûn

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Journal of Neuroinflammation

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Caterina Scuderi

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Claudia Stecca

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Giuseppe Esposito

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Luca Steardo

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Maria Rosaria Carratù

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Marta Valenza

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P2860

Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-gamma

Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors

Palmitoylethanolamide counteracts reactive astrogliosis induced by β-amyloid peptide

Neurotensin receptor involvement in the rise of extracellular glutamate levels and apoptotic nerve cell death in primary cortical cultures after oxygen and glucose deprivation

Microglia and inflammation-mediated neurodegeneration: multiple triggers with a common mechanism

Alzheimer's disease

Mechanisms underlying inflammation in neurodegeneration

The nuclear receptor peroxisome proliferator-activated receptor-alpha mediates the anti-inflammatory actions of palmitoylethanolamide.

N-Acylethanolamines and precursor phospholipids - relation to cell injury.

Palmitoylethanolamide and other anandamide congeners. Proposed role in the diseased brain.

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10.1186/1742-2094-9-49

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Giuseppe Esposito

Maria Rosaria Carratù

Liang-Chuan Lai

Caterina Scuderi

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221691224

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