Mouse model of congenital polycythemia: Homologous replacement of murine gene by mutant human erythropoietin receptor gene
about
The distal region and receptor tyrosines of the Epo receptor are non-essential for in vivo erythropoiesisRecovery and Biodistribution of Ex Vivo Expanded Human Erythroblasts Injected into NOD/SCID/IL2Rγ miceErythropoietin receptor signaling regulates both erythropoiesis and megakaryopoiesis in vivo.EPO receptor gain-of-function causes hereditary polycythemia, alters CD34 cell differentiation and increases circulating endothelial precursors.Advances in understanding the pathogenesis of primary familial and congenital polycythaemiaEpo receptors are not detectable in primary human tumor tissue samplesHematopoietic cell survival signals are elicited through non-tyrosine-containing sequences in the membrane-proximal region of the erythropoietin receptor (EPOR) by a Stat5-dependent pathway.Ligand-induced EpoR internalization is mediated by JAK2 and p85 and is impaired by mutations responsible for primary familial and congenital polycythemiaThe glial cell response is an essential component of hypoxia-induced erythropoiesis in mice.Hypoxia. 5. Hypoxia and hematopoiesis.Blood Collection from Mice and Hematological Analyses on Mouse Blood.Delayed hemoglobin switching and perinatal neocytolysis in mice with gain-of-function erythropoietin receptor.Signals for stress erythropoiesis are integrated via an erythropoietin receptor-phosphotyrosine-343-Stat5 axis.Roles for an Epo receptor Tyr-343 Stat5 pathway in proliferative co-signaling with kit.Lack of expression and function of erythropoietin receptors in the kidney.Endogenous erythropoietin signaling is required for normal neural progenitor cell proliferation.Erythropoietin Signaling Increases Choroidal Macrophages and Cytokine Expression, and Exacerbates Choroidal Neovascularization.Effects of Erythropoietin Receptor Activity on Angiogenesis, Tubular Injury and Fibrosis in Acute Kidney Injury: A "U-Shaped" Relationship.
P2860
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P2860
Mouse model of congenital polycythemia: Homologous replacement of murine gene by mutant human erythropoietin receptor gene
description
2001 nî lūn-bûn
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2001 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունվարին հրատարակված գիտական հոդված
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2001年の論文
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2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
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name
Mouse model of congenital poly ...... n erythropoietin receptor gene
@ast
Mouse model of congenital poly ...... n erythropoietin receptor gene
@en
Mouse model of congenital poly ...... n erythropoietin receptor gene
@nl
type
label
Mouse model of congenital poly ...... n erythropoietin receptor gene
@ast
Mouse model of congenital poly ...... n erythropoietin receptor gene
@en
Mouse model of congenital poly ...... n erythropoietin receptor gene
@nl
prefLabel
Mouse model of congenital poly ...... n erythropoietin receptor gene
@ast
Mouse model of congenital poly ...... n erythropoietin receptor gene
@en
Mouse model of congenital poly ...... n erythropoietin receptor gene
@nl
P2093
P2860
P356
P1476
Mouse model of congenital poly ...... n erythropoietin receptor gene
@en
P2093
P2860
P304
P356
10.1073/PNAS.98.3.986
P407
P577
2001-01-01T00:00:00Z