Novel ethyl methanesulfonate (EMS)-induced null alleles of the Drosophila homolog of LRRK2 reveal a crucial role in endolysosomal functions and autophagy in vivo.
about
Genetic perspective on the role of the autophagy-lysosome pathway in Parkinson diseaseLRRK2 at the interface of autophagosomes, endosomes and lysosomesIdentification of Atg2 and ArfGAP1 as Candidate Genetic Modifiers of the Eye Pigmentation Phenotype of Adaptor Protein-3 (AP-3) Mutants in Drosophila melanogaster.The function of orthologues of the human Parkinson's disease gene LRRK2 across species: implications for disease modelling in preclinical research.Cellular processes associated with LRRK2 function and dysfunctionGenome editing in Drosophila melanogaster: from basic genome engineering to the multipurpose CRISPR-Cas9 system.LRRK2 and Autophagy.Defects in trafficking bridge Parkinson's disease pathology and genetics.Models of LRRK2-Associated Parkinson's Disease.Parkinson disease-associated LRRK2 G2019S transgene disrupts marrow myelopoiesis and peripheral Th17 response.Autophagy impairment in Parkinson's disease.The functional roles of retromer in Parkinson's disease.Vps35 in cooperation with LRRK2 regulates synaptic vesicle endocytosis through the endosomal pathway in Drosophila.Interaction of LRRK2 and α-Synuclein in Parkinson's Disease.Modeling Parkinson's Disease in Drosophila: What Have We Learned for Dominant Traits?
P2860
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P2860
Novel ethyl methanesulfonate (EMS)-induced null alleles of the Drosophila homolog of LRRK2 reveal a crucial role in endolysosomal functions and autophagy in vivo.
description
2014 nî lūn-bûn
@nan
2014 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Novel ethyl methanesulfonate ( ...... nctions and autophagy in vivo.
@ast
Novel ethyl methanesulfonate ( ...... nctions and autophagy in vivo.
@en
Novel ethyl methanesulfonate
@nl
type
label
Novel ethyl methanesulfonate ( ...... nctions and autophagy in vivo.
@ast
Novel ethyl methanesulfonate ( ...... nctions and autophagy in vivo.
@en
Novel ethyl methanesulfonate
@nl
prefLabel
Novel ethyl methanesulfonate ( ...... nctions and autophagy in vivo.
@ast
Novel ethyl methanesulfonate ( ...... nctions and autophagy in vivo.
@en
Novel ethyl methanesulfonate
@nl
P2093
P2860
P356
P1476
Novel ethyl methanesulfonate ( ...... nctions and autophagy in vivo.
@en
P2093
Lok K Leung
Mark W Dodson
Michael A Lizzio
Mohiddin Lone
P2860
P304
P356
10.1242/DMM.017020
P577
2014-10-02T00:00:00Z