The genetics of the E2F family of transcription factors: shared functions and unique roles.
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Impaired DNA damage checkpoint response in MIF-deficient miceCharacterization of cis- and trans-acting elements in the imprinted human SNURF-SNRPN locusInhibition of oncogenic transformation by mammalian Lin-9, a pRB-associated proteinThe transcriptional coregulator RIP140 represses E2F1 activity and discriminates breast cancer subtypesE2f1, E2f2, and E2f3 control E2F target expression and cellular proliferation via a p53-dependent negative feedback loopMicroarray and comparative genomics-based identification of genes and gene regulatory regions of the mouse immune systemSelection of novel mediators of E2F1-induced apoptosis through retroviral expression of an antisense cDNA libraryConservation and evolution of cis-regulatory systems in ascomycete fungiIdentification of genes involved in Ca2+ ionophore A23187-mediated apoptosis and demonstration of a high susceptibility for transcriptional repression of cell cycle genes in B lymphoblasts from a patient with Scott syndromeImpaired DNA replication within progenitor cell pools promotes leukemogenesis.Transcriptional control of mitosis: deregulation and cancerA role for E2F6 in distinguishing G1/S- and G2/M-specific transcriptionDeregulation of Rb-E2F1 axis causes chromosomal instability by engaging the transactivation function of Cdc20-anaphase-promoting complex/cyclosome.Contrasting roles of E2F2 and E2F3 in cardiac neovascularization.Cell size checkpoint control by the retinoblastoma tumor suppressor pathwaySeparation of anti-proliferation and anti-apoptotic functions of retinoblastoma protein through targeted mutations of its A/B domain.E2F-1 induces melanoma cell apoptosis via PUMA up-regulation and Bax translocation.Comparative analysis of E2F family member oncogenic activity.Folate pathway gene expression differs in subtypes of acute lymphoblastic leukemia and influences methotrexate pharmacodynamicsDisruption of mutually negative regulatory feedback loop between interferon-inducible p202 protein and the E2F family of transcription factors in lupus-prone mice.Tandem E2F binding sites in the promoter of the p107 cell cycle regulator control p107 expression and its cellular functions.Coupling of the cell cycle and apoptotic machineries in developing T cells.Transcriptional networks and cellular senescence in human mammary fibroblasts.Diabetes and exocrine pancreatic insufficiency in E2F1/E2F2 double-mutant mice.MicroRNA-493 suppresses tumor growth, invasion and metastasis of lung cancer by regulating E2F1Distinctions in the specificity of E2F function revealed by gene expression signatures.RNAi-mediated knockdown of E2F2 inhibits tumorigenicity of human glioblastoma cells.Folylpolyglutamate synthetase gene transcription is regulated by a multiprotein complex that binds the TEL-AML1 fusion in acute lymphoblastic leukemia.Surprising dependency for retinoblastoma protein in ras-mediated tumorigenesisBMI1 is a target gene of E2F-1 and is strongly expressed in primary neuroblastomas.DNA motifs in human and mouse proximal promoters predict tissue-specific expressionRecombinant adenoviral vectors can induce expression of p73 via the E4-orf6/7 proteinLPLUNC1 inhibits nasopharyngeal carcinoma cell growth via down-regulation of the MAP kinase and cyclin D1/E2F pathwaysTranscriptional repressor functions of Drosophila E2F1 and E2F2 cooperate to inhibit genomic DNA synthesis in ovarian follicle cells.miRNA-205 suppresses melanoma cell proliferation and induces senescence via regulation of E2F1 protein.Cell cycle regulator E2F1 modulates angiogenesis via p53-dependent transcriptional control of VEGF.EWS-FLI1 employs an E2F switch to drive target gene expression.A small molecule disruptor of Rb/Raf-1 interaction inhibits cell proliferation, angiogenesis, and growth of human tumor xenografts in nude mice.The pRb/E2F cell-cycle pathway mediates cell death in Parkinson's diseaseThe CHR promoter element controls cell cycle-dependent gene transcription and binds the DREAM and MMB complexes.
P2860
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P2860
The genetics of the E2F family of transcription factors: shared functions and unique roles.
description
2002 nî lūn-bûn
@nan
2002 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
name
The genetics of the E2F family ...... ed functions and unique roles.
@ast
The genetics of the E2F family ...... ed functions and unique roles.
@en
The genetics of the E2F family ...... ed functions and unique roles.
@nl
type
label
The genetics of the E2F family ...... ed functions and unique roles.
@ast
The genetics of the E2F family ...... ed functions and unique roles.
@en
The genetics of the E2F family ...... ed functions and unique roles.
@nl
prefLabel
The genetics of the E2F family ...... ed functions and unique roles.
@ast
The genetics of the E2F family ...... ed functions and unique roles.
@en
The genetics of the E2F family ...... ed functions and unique roles.
@nl
P1476
The genetics of the E2F family ...... ed functions and unique roles.
@en
P2093
James DeGregori
P304
P356
10.1016/S0304-419X(02)00051-3
P407
P577
2002-06-01T00:00:00Z