Lambda interferon (IFN-lambda), a type III IFN, is induced by viruses and IFNs and displays potent antiviral activity against select virus infections in vivo.
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Interferon lambda: a new sword in cancer immunotherapyIFNL3 mRNA structure is remodeled by a functional non-coding polymorphism associated with hepatitis C virus clearanceImmune signaling by RIG-I-like receptorsAlpha/beta interferon (IFN-alpha/beta)-independent induction of IFN-lambda1 (interleukin-29) in response to Hantaan virus infectionIL-28B/IFN-lambda 3 drives granzyme B loading and significantly increases CTL killing activity in macaquesLambda interferon inhibits human immunodeficiency virus type 1 infection of macrophagesInterleukin-29 functions cooperatively with interferon to induce antiviral gene expression and inhibit hepatitis C virus replicationIFNalpha and IFNlambda differ in their antiproliferative effects and duration of JAK/STAT signaling activityDNA Damage Response and Immune Defense: Links and MechanismsWhat Do We Know about How Hantaviruses Interact with Their Different Hosts?Targeted therapeutics in SLE: emerging strategies to modulate the interferon pathwayInnate Immunity and Immune Evasion by Enterovirus 71Multifunctional roles of leader protein of foot-and-mouth disease viruses in suppressing host antiviral responsesInterferon-λ: Immune Functions at Barrier Surfaces and BeyondImportant Role of the IL-32 Inflammatory Network in the Host Response against Viral InfectionGenetic variants at the IFNL3 locus and their association with hepatitis C virus infections reveal novel insights into host-virus interactionsComparison of antiviral activity of lambda-interferons against HIV replication in macrophagesTumor Progression Locus 2 Promotes Induction of IFNλ, Interferon Stimulated Genes and Antigen-Specific CD8+ T Cell Responses and Protects against Influenza VirusInterferon-inducible antiviral effectorsAntiviral effect of interferon lambda against West Nile virusInterferon- Is Functionally an Interferon but Structurally Related to the Interleukin-10 FamilyCrystal Structure of Human Interferon-λ1 in Complex with Its High-Affinity Receptor Interferon-λR1IFN-λ: A New Inducer of Local Immunity against Cancer and InfectionsImmune Responses to Influenza Virus and Its Correlation to Age and Inherited FactorsInterferon-lambdas: the modulators of antivirus, antitumor, and immune responsesModulation of human plasmacytoid DC function by IFN-lambda1 (IL-29)An image-based genetic assay identifies genes in T1D susceptibility loci controlling cellular antiviral immunity in mouseInterferons and their receptors in birds: a comparison of gene structure, phylogenetic analysis, and cross modulationDifferential Induction of Type I and Type III Interferons by Swine and Human Origin H1N1 Influenza A Viruses in Porcine Airway Epithelial Cells.Pandemic H1N1 2009 influenza A virus induces weak cytokine responses in human macrophages and dendritic cells and is highly sensitive to the antiviral actions of interferons.Interferon induction and function at the mucosal surface.Induction of interferon-λ contributes to TLR3 and RIG-I activation-mediated inhibition of herpes simplex virus type 2 replication in human cervical epithelial cells.Short communication: antiviral activity of porcine IFN-λ3 against porcine epidemic diarrhea virus in vitro.IFN-lambda (IFN-lambda) is expressed in a tissue-dependent fashion and primarily acts on epithelial cells in vivo.MyD88 is required for protection from lethal infection with a mouse-adapted SARS-CoV.IFNL3/4 genotype is associated with altered immune cell populations in peripheral blood in chronic hepatitis C infectionBorrelia burgdorferi RNA induces type I and III interferons via Toll-like receptor 7 and contributes to production of NF-κB-dependent cytokinesPeg-Interferon Lambda Treatment Induces Robust Innate and Adaptive Immunity in Chronic Hepatitis B Patients.Comparative analysis of the lambda-interferons IL-28A and IL-29 regarding their transcriptome and their antiviral properties against hepatitis C virus.Expression of type III interferon (IFN) in the vaginal mucosa is mediated primarily by dendritic cells and displays stronger dependence on NF-kappaB than type I IFNs.
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P2860
Lambda interferon (IFN-lambda), a type III IFN, is induced by viruses and IFNs and displays potent antiviral activity against select virus infections in vivo.
description
2006 nî lūn-bûn
@nan
2006 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
name
Lambda interferon (IFN-lambda) ...... lect virus infections in vivo.
@ast
Lambda interferon (IFN-lambda) ...... lect virus infections in vivo.
@en
Lambda interferon (IFN-lambda) ...... lect virus infections in vivo.
@nl
type
label
Lambda interferon (IFN-lambda) ...... lect virus infections in vivo.
@ast
Lambda interferon (IFN-lambda) ...... lect virus infections in vivo.
@en
Lambda interferon (IFN-lambda) ...... lect virus infections in vivo.
@nl
prefLabel
Lambda interferon (IFN-lambda) ...... lect virus infections in vivo.
@ast
Lambda interferon (IFN-lambda) ...... lect virus infections in vivo.
@en
Lambda interferon (IFN-lambda) ...... lect virus infections in vivo.
@nl
P2093
P2860
P1433
P1476
Lambda interferon (IFN-lambda) ...... lect virus infections in vivo.
@en
P2093
Christina Bartholdy
Kristina Eriksson
Søren R Paludan
P2860
P304
P356
10.1128/JVI.80.9.4501-4509.2006
P407
P577
2006-05-01T00:00:00Z