Characterization of a functional bacterial homologue of sodium-dependent neurotransmitter transporters.
about
Genome sequence of Symbiobacterium thermophilum, an uncultivable bacterium that depends on microbial commensalismThe orphan transporter v7-3 (slc6a15) is a Na+-dependent neutral amino acid transporter (B0AT2)Antidepressant specificity of serotonin transporter suggested by three LeuT-SSRI structuresThe 'permeome' of the malaria parasite: an overview of the membrane transport proteins of Plasmodium falciparum.How LeuT shapes our understanding of the mechanisms of sodium-coupled neurotransmitter transportersA competitive inhibitor traps LeuT in an open-to-out conformation.Insights into transport mechanism from LeuT engineered to transport tryptophanAn in silico analysis of T-box regulated genes and T-box evolution in prokaryotes, with emphasis on prediction of substrate specificity of transportersLigand effects on cross-linking support a conformational mechanism for serotonin transport.Substrate-dependent proton antiport in neurotransmitter:sodium symporters.Ancestry and progeny of nutrient amino acid transporters.Reconstructing a chloride-binding site in a bacterial neurotransmitter transporter homologue.Cytoplasmic permeation pathway of neurotransmitter transporters.Microseconds simulations reveal a new sodium-binding site and the mechanism of sodium-coupled substrate uptake by LeuTMonitoring the function of membrane transport proteins in detergent-solubilized form.Involvement of serotonin transporter extracellular loop 1 in serotonin binding and transport.Identification of a chloride ion binding site in Na+/Cl -dependent transporters.Molecular basis of essential amino acid transport from studies of insect nutrient amino acid transporters of the SLC6 family (NAT-SLC6)How dopamine transporter interacts with dopamine: insights from molecular modeling and simulation.Knockdown of a nutrient amino acid transporter gene LdNAT1 reduces free neutral amino acid contents and impairs Leptinotarsa decemlineata pupationLessons from studies of Symbiobacterium thermophilum, a unique syntrophic bacterium.Chloride binding site of neurotransmitter sodium symporters.Comprehensive analysis of transport proteins encoded within the genome of Bdellovibrio bacteriovorus.A conserved Na(+) binding site of the sodium-coupled neutral amino acid transporter 2 (SNAT2).Substrate and drug binding sites in LeuT.Serotonin and serotonin transport in the regulation of lactation.Structure, function, and plasticity of GABA transporters.A blueprint of ectoine metabolism from the genome of the industrial producer Halomonas elongata DSM 2581 T.Biophysical Approaches to the Study of LeuT, a Prokaryotic Homolog of Neurotransmitter Sodium Symporters.The conserved glutamate (Glu136) in transmembrane domain 2 of the serotonin transporter is required for the conformational switch in the transport cycle.The human dopamine transporter forms a tetramer in the plasma membrane: cross-linking of a cysteine in the fourth transmembrane segment is sensitive to cocaine analogs.A glutamine residue conserved in the neurotransmitter:sodium:symporters is essential for the interaction of chloride with the GABA transporter GAT-1.Cloning and functional expression of the first eukaryotic Na+-tryptophan symporter, AgNAT6.Transmembrane domain 8 of the {gamma}-aminobutyric acid transporter GAT-1 lines a cytoplasmic accessibility pathway into its binding pocket.Switching the clientele: a lysine residing in the C terminus of the serotonin transporter specifies its preference for the coat protein complex II component SEC24CInteraction between lysine 102 and aspartate 338 in the insect amino acid cotransporter KAAT1.State-dependent conformations of the translocation pathway in the tyrosine transporter Tyt1, a novel neurotransmitter:sodium symporter from Fusobacterium nucleatum.The mechanism of a neurotransmitter:sodium symporter--inward release of Na+ and substrate is triggered by substrate in a second binding site.Combining structure-based pharmacophore and in silico approaches to discover novel selective serotonin reuptake inhibitors.The substrates of the gamma-aminobutyric acid transporter GAT-1 induce structural rearrangements around the interface of transmembrane domains 1 and 6.
P2860
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P2860
Characterization of a functional bacterial homologue of sodium-dependent neurotransmitter transporters.
description
2003 nî lūn-bûn
@nan
2003 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Characterization of a function ...... neurotransmitter transporters.
@ast
Characterization of a function ...... neurotransmitter transporters.
@en
Characterization of a function ...... neurotransmitter transporters.
@nl
type
label
Characterization of a function ...... neurotransmitter transporters.
@ast
Characterization of a function ...... neurotransmitter transporters.
@en
Characterization of a function ...... neurotransmitter transporters.
@nl
prefLabel
Characterization of a function ...... neurotransmitter transporters.
@ast
Characterization of a function ...... neurotransmitter transporters.
@en
Characterization of a function ...... neurotransmitter transporters.
@nl
P2093
P2860
P356
P1476
Characterization of a function ...... neurotransmitter transporters.
@en
P2093
Andreas Androutsellis-Theotokis
Gary Rudnick
Jonathan A Javitch
Kenji Ueda
Matthew L Beckman
Naomi R Goldberg
Shonit Das
Teruhiko Beppu
P2860
P304
12703-12709
P356
10.1074/JBC.M206563200
P407
P577
2003-02-04T00:00:00Z