Trans-ethnic fine-mapping of lipid loci identifies population-specific signals and allelic heterogeneity that increases the trait variance explained. - Wikidata - wikimedia - TriplyDB

Trans-ethnic fine-mapping of lipid loci identifies population-specific signals and allelic heterogeneity that increases the trait variance explained.

Trans-ethnic fine-mapping of lipid loci identifies population-specific signals and allelic heterogeneity that increases the trait variance explained.

http://www.wikidata.org/entity/Q34649888

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Insights into blood lipids from rare variant discovery Progress in understanding the genomic basis for adverse drug reactions: a comprehensive review and focus on the role of ethnicity Trans-ethnic genome-wide association studies: advantages and challenges of mapping in diverse populations.Genome-wide association study of ancestry-specific TB risk in the South African Coloured population Risk loci for chronic obstructive pulmonary disease: a genome-wide association study and meta-analysis.Fine-mapping of lipid regions in global populations discovers ethnic-specific signals and refines previously identified lipid loci.Genetic associations with lipoprotein subfraction measures differ by ethnicity in the multi-ethnic study of atherosclerosis (MESA).Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.Integrating functional data to prioritize causal variants in statistical fine-mapping studies.Genetic effects influencing risk for major depressive disorder in China and Europe.Amerindian-specific regions under positive selection harbour new lipid variants in Latinos.Genetic architecture of lipid traits changes over time and differs by race: Princeton Lipid Follow-up Study.Fine mapping the CETP region reveals a common intronic insertion associated to HDL-C Sequence variation in TMEM18 in association with body mass index: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study.Identifying causal variants at loci with multiple signals of association Genome-wide family-based linkage analysis of exome chip variants and cardiometabolic risk.Generalization and dilution of association results from European GWAS in populations of non-European ancestry: the PAGE study.Gene-based sequencing identifies lipid-influencing variants with ethnicity-specific effects in African Americans.rs7903146 polymorphism at transcription factor 7 like 2 gene is associated with total cholesterol and lipoprotein profile in HIV/hepatitis C virus-coinfected patients.Genome-wide meta-analysis identifies multiple novel associations and ethnic heterogeneity of psoriasis susceptibility.The effects of electronic medical record phenotyping details on genetic association studies: HDL-C as a case study.Advances in exercise, fitness, and performance genomics in 2014.Genome-Wide Association Analysis for Blood Lipid Traits Measured in Three Pig Populations Reveals a Substantial Level of Genetic Heterogeneity.Evaluating the Performance of Fine-Mapping Strategies at Common Variant GWAS Loci.Fine-scale population structure of Malays in Peninsular Malaysia and Singapore and implications for association studies Genetic architecture of colorectal cancer.Integration of multiethnic fine-mapping and genomic annotation to prioritize candidate functional SNPs at prostate cancer susceptibility regions.EIF3G is associated with narcolepsy across ethnicities.Exome-wide association analysis reveals novel coding sequence variants associated with lipid traits in Chinese.Trans-ethnic study design approaches for fine-mapping.Genome-wide characterization of shared and distinct genetic components that influence blood lipid levels in ethnically diverse human populations Genome-wide association study of colorectal cancer in Hispanics.Fine Mapping and Identification of BMI Loci in African Americans.Genetic association with lipids in Filipinos: waist circumference modifies an APOA5 effect on triglyceride levels Endothelin Type A Receptor Genotype is a Determinant of Quantitative Traits of Metabolic Syndrome in Asian Hypertensive Families: A SAPPHIRe Study.Deep targeted sequencing of 12 breast cancer susceptibility regions in 4611 women across four different ethnicities.Multiple linear combination (MLC) regression tests for common variants adapted to linkage disequilibrium structure Trans-ethnic follow-up of breast cancer GWAS hits using the preferential linkage disequilibrium approach.Proprotein convertases subtilisin/kexin type 9, an enzyme turned escort protein: hepatic and extra hepatic functions.Update on APOA5 Genetics: Toward a Better Understanding of Its Physiological Impact.

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Trans-ethnic fine-mapping of lipid loci identifies population-specific signals and allelic heterogeneity that increases the trait variance explained.

http://www.wikidata.org/entity/Q34649888

description

2013 nî lūn-bûn

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2013 թուականի Մարտին հրատարակուած գիտական յօդուած

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2013 թվականի մարտին հրատարակված գիտական հոդված

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年论文

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Trans-ethnic fine-mapping of l ...... the trait variance explained.

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Trans-ethnic fine-mapping of l ...... the trait variance explained.

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Trans-ethnic fine-mapping of l ...... the trait variance explained.

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Trans-ethnic fine-mapping of l ...... the trait variance explained.

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Trans-ethnic fine-mapping of l ...... the trait variance explained.

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Trans-ethnic fine-mapping of l ...... the trait variance explained.

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JOURNAL.PGEN.1003379

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Alan B Feranil

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Alena Stančáková

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Alicia M Young

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Amy J Swift

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Antero Y Kesäniemi

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Aravinda Chakravarti

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Barbara Cochran

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Cara L Carty

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Chao A Hsiung

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Charles B Eaton

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P2860

Fine mapping of five loci associated with low-density lipoprotein cholesterol detects variants that double the explained heritability

The proprotein convertase (PC) PCSK9 is inactivated by furin and/or PC5/6A: functional consequences of natural mutations and post-translational modifications

Type III hyperlipoproteinemia and spontaneous atherosclerosis in mice resulting from gene replacement of mouse Apoe with human Apoe*2

Genome-wide association studies for complex traits: consensus, uncertainty and challenges

Common variants at 30 loci contribute to polygenic dyslipidemia

Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

Biological, clinical and population relevance of 95 loci for blood lipids

Hundreds of variants clustered in genomic loci and biological pathways affect human height

From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus

Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans

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Jaakko Tuomilehto

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Charles Kooperberg

Loic Le Marchand

Alena Stančáková

Johanna Kuusisto

Thomas Quertermous

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2013-03-21T00:00:00Z

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236106157

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