Backsteps induced by nucleotide analogs suggest the front head of kinesin is gated by strain
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The Mechanochemical Cycle of Mammalian Kinesin-2 KIF3A/B under Load.The forward and backward stepping processes of kinesin are gated by ATP bindingTwo distinct modes of processive kinesin movement in mixtures of ATP and AMP-PNP.A kinesin-13 mutant catalytically depolymerizes microtubules in ADPProcessive movement by a kinesin heterodimer with an inactivating mutation in one head.Mechanism of cooperative behaviour in systems of slow and fast molecular motors.Direct observation of the binding state of the kinesin head to the microtubule.The AAA3 domain of cytoplasmic dynein acts as a switch to facilitate microtubule release.Kinesin Motor Enzymology: Chemistry, Structure, and Physics of Nanoscale Molecular MachinesInsights into the Mechanical Properties of the Kinesin Neck Linker Domain from Sequence Analysis and Molecular Dynamics SimulationsDissection of kinesin's processivity.Kinesin's step dissected with single-motor FRET.Kinesin's neck-linker determines its ability to navigate obstacles on the microtubule surfaceCrystal structure of Zen4 in the apo state reveals a missing conformation of kinesin.Mechanical properties of organelles driven by microtubule-dependent molecular motors in living cells.Mechanism of processive movement of monomeric and dimeric kinesin molecules.DNA unwinding by ring-shaped T4 helicase gp41 is hindered by tension on the occluded strandA seesaw model for intermolecular gating in the kinesin motor proteinA universal pathway for kinesin stepping.High-resolution structures of kinesin on microtubules provide a basis for nucleotide-gated force-generationEg5 steps it up!Processivity of the kinesin-2 KIF3A results from rear head gating and not front head gatingExamining kinesin processivity within a general gating framework.Kinesin motor mechanics: binding, stepping, tracking, gating, and limping.A structural perspective on the dynamics of kinesin motors.Internal strain regulates the nucleotide binding site of the kinesin leading headMicrotubule capture by mitotic kinesin centromere protein E (CENP-E).Kinesin is an evolutionarily fine-tuned molecular ratchet-and-pawl device of decisively locked direction.Mechanical control of the directional stepping dynamics of the kinesin motor.Getting in sync with dimeric Eg5. Initiation and regulation of the processive run.To step or not to step? How biochemistry and mechanics influence processivity in Kinesin and Eg5.The Kinesin-1 Chemomechanical Cycle: Stepping Toward a Consensus.Dwell time symmetry in random walks and molecular motors.A mobile kinesin-head intermediate during the ATP-waiting state.Alternating-site mechanism of kinesin-1 characterized by single-molecule FRET using fluorescent ATP analogues.Why kinesin is so processive.Energetics of kinesin-1 stepping mechanism.Single molecule measurements of F1-ATPase reveal an interdependence between the power stroke and the dwell durationOn the origin of kinesin limping.Walking the walk: how kinesin and dynein coordinate their steps.
P2860
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P2860
Backsteps induced by nucleotide analogs suggest the front head of kinesin is gated by strain
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2006 nî lūn-bûn
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2006 թուականի Մայիսին հրատարակուած գիտական յօդուած
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2006 թվականի մայիսին հրատարակված գիտական հոդված
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2006年の論文
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2006年論文
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2006年論文
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2006年論文
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2006年論文
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2006年論文
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2006年论文
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Backsteps induced by nucleotid ...... of kinesin is gated by strain
@ast
Backsteps induced by nucleotid ...... of kinesin is gated by strain
@en
Backsteps induced by nucleotid ...... of kinesin is gated by strain
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Backsteps induced by nucleotid ...... of kinesin is gated by strain
@ast
Backsteps induced by nucleotid ...... of kinesin is gated by strain
@en
Backsteps induced by nucleotid ...... of kinesin is gated by strain
@nl
prefLabel
Backsteps induced by nucleotid ...... of kinesin is gated by strain
@ast
Backsteps induced by nucleotid ...... of kinesin is gated by strain
@en
Backsteps induced by nucleotid ...... of kinesin is gated by strain
@nl
P2860
P356
P1476
Backsteps induced by nucleotid ...... of kinesin is gated by strain
@en
P2093
Nicholas R Guydosh
P2860
P304
P356
10.1073/PNAS.0600931103
P407
P577
2006-05-12T00:00:00Z