Clinical evaluation of ganaxolone in pediatric and adolescent patients with refractory epilepsy. - Wikidata - wikimedia - TriplyDB

Clinical evaluation of ganaxolone in pediatric and adolescent patients with refractory epilepsy.

Clinical evaluation of ganaxolone in pediatric and adolescent patients with refractory epilepsy.

http://www.wikidata.org/entity/Q34651475

about

Ganaxolone add-on for drug-resistant epilepsy Neurosteroids: endogenous role in the human brain and therapeutic potentials Hormonal aspects of epilepsy.Allopregnanolone and neuroinflammation: a focus on multiple sclerosis.Simultaneous quantification of GABAergic 3alpha,5alpha/3alpha,5beta neuroactive steroids in human and rat serum.Impaired neurosteroid synthesis in multiple sclerosis.Modulation of the GABAergic pathway for the treatment of fragile X syndrome.Mutations of protocadherin 19 in female epilepsy (PCDH19-FE) lead to allopregnanolone deficiency.Role of anticonvulsant and antiepileptogenic neurosteroids in the pathophysiology and treatment of epilepsy.Differential interactions engendered by benzodiazepine and neuroactive steroid combinations on schedule-controlled responding in rats.Neuroendocrine aspects of catamenial epilepsy Pregnenolone sulfate as a modulator of synaptic plasticity.Neurosteroidogenesis Today: Novel Targets for Neuroactive Steroid Synthesis and Action and Their Relevance for Translational Research.Modulation of Immunity and the Inflammatory Response: A New Target for Treating Drug-resistant Epilepsy.New and investigational antiepileptic drugs.Clinical Potential of Neurosteroids for CNS Disorders.Pharmacotherapy of epilepsy: newly approved and developmental agents.Hormonal therapy for epilepsy.Emerging drugs for focal epilepsy.Investigating psychotropic properties of antiepileptic drugs.Improving Outcomes in Infantile Spasms: Role of Pharmacotherapy.The Impact of Next-Generation Sequencing on the Diagnosis and Treatment of Epilepsy in Paediatric Patients.Treatment of Lennox-Gastaut syndrome: overview and recent findings.A randomized double-blind, placebo-controlled trial of ganaxolone in children and adolescents with fragile X syndrome.Ganaxolone: A New Treatment for Neonatal Seizures.Synthesis and pharmacological evaluation of neurosteroid photoaffinity ligands.Randomized, double-blind, placebo-controlled phase 2 study of ganaxolone as add-on therapy in adults with uncontrolled partial-onset seizures.Benzodiazepine and neuroactive steroid combinations in rats: anxiolytic-like and discriminative stimulus effects.Genetic and Molecular Regulation of Extrasynaptic GABA-A Receptors in the Brain: Therapeutic Insights for Epilepsy.Antiepileptic drugs in development pipeline: A recent update.

P2860

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P2860

Clinical evaluation of ganaxolone in pediatric and adolescent patients with refractory epilepsy.

http://www.wikidata.org/entity/Q34651475

description

2007 nî lūn-bûn

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2007 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2007 թվականի հուլիսին հրատարակված գիտական հոդված

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2007年の論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年论文

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name

Clinical evaluation of ganaxol ...... ents with refractory epilepsy.

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Clinical evaluation of ganaxol ...... ents with refractory epilepsy.

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Clinical evaluation of ganaxol ...... ents with refractory epilepsy.

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type

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Clinical evaluation of ganaxol ...... ents with refractory epilepsy.

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Clinical evaluation of ganaxol ...... ents with refractory epilepsy.

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Clinical evaluation of ganaxol ...... ents with refractory epilepsy.

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Clinical evaluation of ganaxol ...... ents with refractory epilepsy.

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Clinical evaluation of ganaxol ...... ents with refractory epilepsy.

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Clinical evaluation of ganaxol ...... ents with refractory epilepsy.

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J.1528-1167.2007.01182.X

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Clinical evaluation of ganaxol ...... ents with refractory epilepsy.

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Christine Soufflet

http://www.w3.org/2001/XMLSchema#string

Earl Giller

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Elisabeth Rey

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Julia Tsai

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Ken Shaw

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Olivier Dulac

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Vincent A Pieribone

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P2860

Endogenous neurosteroids regulate GABAA receptors through two discrete transmembrane sites.

Neurosteroids: a new brain function?

Assessment of ganaxolone's anticonvulsant activity using a randomized, double-blind, presurgical trial design. Ganaxolone Presurgical Study Group.

Ganaxolone for treating intractable infantile spasms: a multicenter, open-label, add-on trial.

Effect of ganaxolone on flurothyl seizures in developing rats.

Ganaxolone, a selective, high-affinity steroid modulator of the gamma-aminobutyric acid-A receptor, exacerbates seizures in animal models of absence.

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