Notch signaling, gamma-secretase inhibitors, and cancer therapy.
about
Proteolytic cleavage of protein tyrosine phosphatase mu regulates glioblastoma cell migrationHPV-p53-miR-34a axis in HPV-associated cancersMolecular classification of gastric cancer: Towards a pathway-driven targeted therapyEvasion of anti-growth signaling: A key step in tumorigenesis and potential target for treatment and prophylaxis by natural compounds.Targeting the Notch signaling pathway in cancer therapeuticsCan nanomedicines kill cancer stem cells?Development of nanoparticles incorporating a novel liposomal membrane destabilization peptide for efficient release of cargos into cancer cellsAlterations of the Notch pathway in lung cancer.Therapeutic targets of triple-negative breast cancer: a reviewPotential therapeutic approaches for modulating expression and accumulation of defective lamin A in laminopathies and age-related diseasesDll1- and dll4-mediated notch signaling are required for homeostasis of intestinal stem cellsΓ-secretase components as predictors of breast cancer outcomeThe novel gamma secretase inhibitor RO4929097 reduces the tumor initiating potential of melanomaMolecular cues on obesity signals, tumor markers and endometrial cancer.Preventive effect of Notch signaling inhibition by a gamma-secretase inhibitor on peritoneal dialysis fluid-induced peritoneal fibrosis in ratsComparison of dynamic contrast-enhanced MR, ultrasound and optical imaging modalities to evaluate the antiangiogenic effect of PF-03084014 and sunitinib.A novel function of DELTA-NOTCH signalling mediates the transition from proliferation to neurogenesis in neural progenitor cellsProteomic profiling of gamma-secretase substrates and mapping of substrate requirementsNotch1 activation is a poor prognostic factor in patients with gastric cancer.NOTCH ligands JAG1 and JAG2 as critical pro-survival factors in childhood medulloblastoma.Pathogenesis of ovarian cancer: clues from selected overexpressed genes.NOTCH inhibits osteoblast formation in inflammatory arthritis via noncanonical NF-κB.γ-secretase inhibitor DAPT sensitizes t-AUCB-induced apoptosis of human glioblastoma cells in vitro via blocking the p38 MAPK/MAPKAPK2/Hsp27 pathwayPresenilin/gamma-Secretase and Inflammation.NOTCH2 in breast cancer: association of SNP rs11249433 with gene expression in ER-positive breast tumors without TP53 mutations.Notch3 overexpression is related to the recurrence of ovarian cancer and confers resistance to carboplatin.Tumor-supportive and osteoclastogenic changes induced by breast cancer-derived factors are reversed by inhibition of {gamma}-secretase.Jagged1 expression regulated by Notch3 and Wnt/β-catenin signaling pathways in ovarian cancer.Multi-targeted therapy of cancer by niclosamide: A new application for an old drug.Targeting Notch signaling pathway to overcome drug resistance for cancer therapyA cell-surface β-hydroxylase is a biomarker and therapeutic target for hepatocellular carcinomaInitial testing (stage 1) of the notch inhibitor PF-03084014, by the pediatric preclinical testing program.Targeting Notch pathway induces growth inhibition and differentiation of neuroblastoma cells.The pathological significance of Notch1 in oral squamous cell carcinoma.Role of Notch and its oncogenic signaling crosstalk in breast cancer.HES1, a target of Notch signaling, is elevated in canine osteosarcoma, but reduced in the most aggressive tumorsThe role of Notch signaling pathway in epithelial-mesenchymal transition (EMT) during development and tumor aggressivenessRegulation of non-classical FGF1 release and FGF-dependent cell transformation by CBF1-mediated notch signaling.HES1-mediated inhibition of Notch1 signaling by a Gemini vitamin D analog leads to decreased CD44(+)/CD24(-/low) tumor-initiating subpopulation in basal-like breast cancer.Notch signaling activation is critical to the development of neuropathic pain.
P2860
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P2860
Notch signaling, gamma-secretase inhibitors, and cancer therapy.
description
2007 nî lūn-bûn
@nan
2007 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի մարտին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Notch signaling, gamma-secretase inhibitors, and cancer therapy.
@ast
Notch signaling, gamma-secretase inhibitors, and cancer therapy.
@en
Notch signaling, gamma-secretase inhibitors, and cancer therapy.
@nl
type
label
Notch signaling, gamma-secretase inhibitors, and cancer therapy.
@ast
Notch signaling, gamma-secretase inhibitors, and cancer therapy.
@en
Notch signaling, gamma-secretase inhibitors, and cancer therapy.
@nl
prefLabel
Notch signaling, gamma-secretase inhibitors, and cancer therapy.
@ast
Notch signaling, gamma-secretase inhibitors, and cancer therapy.
@en
Notch signaling, gamma-secretase inhibitors, and cancer therapy.
@nl
P1433
P1476
Notch signaling, gamma-secretase inhibitors, and cancer therapy.
@en
P2093
Ie-Ming Shih
Tian-Li Wang
P304
P356
10.1158/0008-5472.CAN-06-3958
P407
P577
2007-03-01T00:00:00Z