Nonenzymatic proton handling by carbonic anhydrase II during H+-lactate cotransport via monocarboxylate transporter 1.
about
The spatial organization of proton and lactate transport in a rat brain tumorDuodenal acidity "sensing" but not epithelial HCO3- supply is critically dependent on carbonic anhydrase II expressionRole of carbonic anhydrase IV in the bicarbonate-mediated activation of murine and human spermT tubules and surface membranes provide equally effective pathways of carbonic anhydrase-facilitated lactic acid transport in skeletal muscle.Transport activity of the sodium bicarbonate cotransporter NBCe1 is enhanced by different isoforms of carbonic anhydraseIntramolecular proton shuttle supports not only catalytic but also noncatalytic function of carbonic anhydrase II.Analysis of the binding moiety mediating the interaction between monocarboxylate transporters and carbonic anhydrase IITransport activity of the high-affinity monocarboxylate transporter MCT2 is enhanced by extracellular carbonic anhydrase IV but not by intracellular carbonic anhydrase IIIncreased water flux induced by an aquaporin-1/carbonic anhydrase II interactionProtons migrate along interfacial water without significant contributions from jumps between ionizable groups on the membrane surfaceBicarbonate, NBCe1, NHE, and carbonic anhydrase activity enhance lactate-H+ transport in bovine corneal endothelium.GPI-anchored carbonic anhydrase IV displays both intra- and extracellular activity in cRNA-injected oocytes and in mouse neurons.Carbonic anhydrase II binds to and increases the activity of the epithelial sodium-proton exchanger, NHE3Fluid transport by the cornea endothelium is dependent on buffering lactic acid efflux.Tumour hypoxia induces a metabolic shift causing acidosis: a common feature in cancer.Red fluorescent protein pH biosensor to detect concentrative nucleoside transportIntracellular and extracellular carbonic anhydrases cooperate non-enzymatically to enhance activity of monocarboxylate transporters.Lactate-H⁺ transport is a significant component of the in vivo corneal endothelial pump.Bicarbonate transport in health and disease.Selective inhibition of human carbonic anhydrase IX in Xenopus oocytes and MDA-MB-231 breast cancer cells.Carbon dioxide and water transport through plant aquaporins.General requirement for harvesting antennae at ca and h channels and transporters.Transport metabolons with carbonic anhydrases.The role of membrane acid/base transporters and carbonic anhydrases for cellular pH and metabolic processes.Activity and distribution of intracellular carbonic anhydrase II and their effects on the transport activity of anion exchanger AE1/SLC4A1.Functional interaction between bicarbonate transporters and carbonic anhydrase modulates lactate uptake into mouse cardiomyocytes.Bicarbonate-dependent and bicarbonate-independent mechanisms contribute to nondiffusive uptake of acetate in the ruminal epithelium of sheep.Integration of a 'proton antenna' facilitates transport activity of the monocarboxylate transporter MCT4.Lactate flux in astrocytes is enhanced by a non-catalytic action of carbonic anhydrase II.Acute feedback control of astrocytic glycolysis by lactate.Carbonic Anhydrase IX (CAIX), Cancer, and Radiation Responsiveness.Cytosolic H+ microdomain developed around AE1 during AE1-mediated Cl-/HCO3- exchange.Carbonic Anhydrases: Role in pH Control and Cancer.A surface proton antenna in carbonic anhydrase II supports lactate transport in cancer cells.
P2860
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P2860
Nonenzymatic proton handling by carbonic anhydrase II during H+-lactate cotransport via monocarboxylate transporter 1.
description
2008 nî lūn-bûn
@nan
2008 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Nonenzymatic proton handling b ...... monocarboxylate transporter 1.
@ast
Nonenzymatic proton handling b ...... monocarboxylate transporter 1.
@en
Nonenzymatic proton handling b ...... monocarboxylate transporter 1.
@nl
type
label
Nonenzymatic proton handling b ...... monocarboxylate transporter 1.
@ast
Nonenzymatic proton handling b ...... monocarboxylate transporter 1.
@en
Nonenzymatic proton handling b ...... monocarboxylate transporter 1.
@nl
prefLabel
Nonenzymatic proton handling b ...... monocarboxylate transporter 1.
@ast
Nonenzymatic proton handling b ...... monocarboxylate transporter 1.
@en
Nonenzymatic proton handling b ...... monocarboxylate transporter 1.
@nl
P2860
P356
P1476
Nonenzymatic proton handling b ...... monocarboxylate transporter 1.
@en
P2093
Holger M Becker
Joachim W Deitmer
P2860
P304
21655-21667
P356
10.1074/JBC.M802134200
P407
P577
2008-06-06T00:00:00Z