ATP citrate lyase: activation and therapeutic implications in non-small cell lung cancer.
about
Acetylation stabilizes ATP-citrate lyase to promote lipid biosynthesis and tumor growthIdentification of the citrate-binding site of human ATP-citrate lyase using X-ray crystallographyPolyunsaturated fatty acid metabolism in prostate cancerThe diverse role of the PPARγ coactivator 1 family of transcriptional coactivators in cancerPPARδ activation acts cooperatively with 3-phosphoinositide-dependent protein kinase-1 to enhance mammary tumorigenesisProfiling Y561-dependent and -independent substrates of CSF-1R in epithelial cellsReductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxiaTumor macroenvironment and metabolism.Associations among Metabolism, Circadian Rhythm and Age-Associated DiseasesRole of insulin-like growth factor binding protein 2 in lung adenocarcinoma: IGF-independent antiapoptotic effect via caspase-3Identification of ATP citrate lyase as a positive regulator of glycolytic function in glioblastomasMetabolic genes in cancer: their roles in tumor progression and clinical implicationsmTORC2 in the center of cancer metabolic reprogrammingInterplay between epigenetics and metabolism in oncogenesis: mechanisms and therapeutic approachesDeficiency in hepatic ATP-citrate lyase affects VLDL-triglyceride mobilization and liver fatty acid composition in miceAkt-dependent metabolic reprogramming regulates tumor cell histone acetylationLiverome: a curated database of liver cancer-related gene signatures with self-contained context informationA two-way street: reciprocal regulation of metabolism and signalling.Mutations in CIC and IDH1 cooperatively regulate 2-hydroxyglutarate levels and cell clonogenicityActivation of ATP citrate lyase by mTOR signal induces disturbed lipid metabolism in hepatitis B virus pre-S2 mutant tumorigenesis.Identification of c-Src tyrosine kinase substrates in platelet-derived growth factor receptor signaling.ATP citrate lyase mediates resistance of colorectal cancer cells to SN38.Functional polymorphisms of ATP citrate lyase gene predicts clinical outcome of patients with advanced colorectal cancer.Signalling mechanisms regulating phenotypic changes in breast cancer cells.Cancer cells differentially activate and thrive on de novo lipid synthesis pathways in a low-lipid environment.Metabolic alterations and targeted therapies in prostate cancer.Is acetylation a metabolic rheostat that regulates skeletal muscle insulin action?Prognostic Value of Malic Enzyme and ATP-Citrate Lyase in Non-Small Cell Lung Cancer of the Young and the Elderly.ACLY and ACC1 Regulate Hypoxia-Induced Apoptosis by Modulating ETV4 via α-ketoglutarate.ATP citrate lyase expression is associated with advanced stage and prognosis in gastric adenocarcinoma.Glucose-dependent acetylation of Rictor promotes targeted cancer therapy resistance.Repression of endometrial tumor growth by targeting SREBP1 and lipogenesisInhibition of lung cancer growth: ATP citrate lyase knockdown and statin treatment leads to dual blockade of mitogen-activated protein kinase (MAPK) and phosphatidylinositol-3-kinase (PI3K)/AKT pathways.Dysregulated lipid metabolism in cancer.Key Roles of Glutamine Pathways in Reprogramming the Cancer Metabolism.The potential utility of acetyltanshinone IIA in the treatment of HER2-overexpressed breast cancer: Induction of cancer cell death by targeting apoptotic and metabolic signaling pathwaysThe Emerging Hallmarks of Cancer MetabolismYeast and cancer cells - common principles in lipid metabolism.Prognostic and therapeutic implications of increased ATP citrate lyase expression in human epithelial ovarian cancer.AMPK regulates NADPH homeostasis to promote tumour cell survival during energy stress.
P2860
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P2860
ATP citrate lyase: activation and therapeutic implications in non-small cell lung cancer.
description
2008 nî lūn-bûn
@nan
2008 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
ATP citrate lyase: activation and therapeutic implications in non-small cell lung cancer.
@ast
ATP citrate lyase: activation and therapeutic implications in non-small cell lung cancer.
@en
ATP citrate lyase: activation and therapeutic implications in non-small cell lung cancer.
@nl
type
label
ATP citrate lyase: activation and therapeutic implications in non-small cell lung cancer.
@ast
ATP citrate lyase: activation and therapeutic implications in non-small cell lung cancer.
@en
ATP citrate lyase: activation and therapeutic implications in non-small cell lung cancer.
@nl
prefLabel
ATP citrate lyase: activation and therapeutic implications in non-small cell lung cancer.
@ast
ATP citrate lyase: activation and therapeutic implications in non-small cell lung cancer.
@en
ATP citrate lyase: activation and therapeutic implications in non-small cell lung cancer.
@nl
P2093
P1433
P1476
ATP citrate lyase: activation and therapeutic implications in non-small cell lung cancer
@en
P2093
Erika Miyagi
Fumika Inazuka
Ken Nakagawa
Kimie Nomura
Masaaki Matsuura
Masaru Ushijima
Sakae Okumura
Tadahito Narita
Tetsuo Mashima
Toshiro Migita
P304
P356
10.1158/0008-5472.CAN-08-1235
P407
P577
2008-10-01T00:00:00Z