ATP citrate lyase: activation and therapeutic implications in non-small cell lung cancer. - Wikidata - wikimedia - TriplyDB

ATP citrate lyase: activation and therapeutic implications in non-small cell lung cancer.

ATP citrate lyase: activation and therapeutic implications in non-small cell lung cancer.

http://www.wikidata.org/entity/Q34657399

about

Acetylation stabilizes ATP-citrate lyase to promote lipid biosynthesis and tumor growth Identification of the citrate-binding site of human ATP-citrate lyase using X-ray crystallography Polyunsaturated fatty acid metabolism in prostate cancer The diverse role of the PPARγ coactivator 1 family of transcriptional coactivators in cancer PPARδ activation acts cooperatively with 3-phosphoinositide-dependent protein kinase-1 to enhance mammary tumorigenesis Profiling Y561-dependent and -independent substrates of CSF-1R in epithelial cells Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia Tumor macroenvironment and metabolism.Associations among Metabolism, Circadian Rhythm and Age-Associated Diseases Role of insulin-like growth factor binding protein 2 in lung adenocarcinoma: IGF-independent antiapoptotic effect via caspase-3 Identification of ATP citrate lyase as a positive regulator of glycolytic function in glioblastomas Metabolic genes in cancer: their roles in tumor progression and clinical implications mTORC2 in the center of cancer metabolic reprogramming Interplay between epigenetics and metabolism in oncogenesis: mechanisms and therapeutic approaches Deficiency in hepatic ATP-citrate lyase affects VLDL-triglyceride mobilization and liver fatty acid composition in mice Akt-dependent metabolic reprogramming regulates tumor cell histone acetylation Liverome: a curated database of liver cancer-related gene signatures with self-contained context information A two-way street: reciprocal regulation of metabolism and signalling.Mutations in CIC and IDH1 cooperatively regulate 2-hydroxyglutarate levels and cell clonogenicity Activation of ATP citrate lyase by mTOR signal induces disturbed lipid metabolism in hepatitis B virus pre-S2 mutant tumorigenesis.Identification of c-Src tyrosine kinase substrates in platelet-derived growth factor receptor signaling.ATP citrate lyase mediates resistance of colorectal cancer cells to SN38.Functional polymorphisms of ATP citrate lyase gene predicts clinical outcome of patients with advanced colorectal cancer.Signalling mechanisms regulating phenotypic changes in breast cancer cells.Cancer cells differentially activate and thrive on de novo lipid synthesis pathways in a low-lipid environment.Metabolic alterations and targeted therapies in prostate cancer.Is acetylation a metabolic rheostat that regulates skeletal muscle insulin action?Prognostic Value of Malic Enzyme and ATP-Citrate Lyase in Non-Small Cell Lung Cancer of the Young and the Elderly.ACLY and ACC1 Regulate Hypoxia-Induced Apoptosis by Modulating ETV4 via α-ketoglutarate.ATP citrate lyase expression is associated with advanced stage and prognosis in gastric adenocarcinoma.Glucose-dependent acetylation of Rictor promotes targeted cancer therapy resistance.Repression of endometrial tumor growth by targeting SREBP1 and lipogenesis Inhibition of lung cancer growth: ATP citrate lyase knockdown and statin treatment leads to dual blockade of mitogen-activated protein kinase (MAPK) and phosphatidylinositol-3-kinase (PI3K)/AKT pathways.Dysregulated lipid metabolism in cancer.Key Roles of Glutamine Pathways in Reprogramming the Cancer Metabolism.The potential utility of acetyltanshinone IIA in the treatment of HER2-overexpressed breast cancer: Induction of cancer cell death by targeting apoptotic and metabolic signaling pathways The Emerging Hallmarks of Cancer Metabolism Yeast and cancer cells - common principles in lipid metabolism.Prognostic and therapeutic implications of increased ATP citrate lyase expression in human epithelial ovarian cancer.AMPK regulates NADPH homeostasis to promote tumour cell survival during energy stress.

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P2860

ATP citrate lyase: activation and therapeutic implications in non-small cell lung cancer.

http://www.wikidata.org/entity/Q34657399

description

2008 nî lūn-bûn

@nan

2008 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

@zh-hk

2008年論文

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2008年論文

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2008年论文

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name

ATP citrate lyase: activation and therapeutic implications in non-small cell lung cancer.

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ATP citrate lyase: activation and therapeutic implications in non-small cell lung cancer.

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ATP citrate lyase: activation and therapeutic implications in non-small cell lung cancer.

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type

label

ATP citrate lyase: activation and therapeutic implications in non-small cell lung cancer.

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ATP citrate lyase: activation and therapeutic implications in non-small cell lung cancer.

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ATP citrate lyase: activation and therapeutic implications in non-small cell lung cancer.

@nl

prefLabel

ATP citrate lyase: activation and therapeutic implications in non-small cell lung cancer.

@ast

ATP citrate lyase: activation and therapeutic implications in non-small cell lung cancer.

@en

ATP citrate lyase: activation and therapeutic implications in non-small cell lung cancer.

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0008-5472.CAN-08-1235

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Cancer Research

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ATP citrate lyase: activation and therapeutic implications in non-small cell lung cancer

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Erika Miyagi

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Fumika Inazuka

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Ken Nakagawa

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Kimie Nomura

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Masaaki Matsuura

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Masaru Ushijima

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Sakae Okumura

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Tadahito Narita

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Tetsuo Mashima

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Toshiro Migita

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8547-8554

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scholarly article

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10.1158/0008-5472.CAN-08-1235

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20

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68

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Hiroyuki Seimiya

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2008-10-01T00:00:00Z

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23387155

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