Recognition of fresh human tumor by human peripheral blood lymphocytes transduced with a bicistronic retroviral vector encoding a murine anti-p53 TCR.
about
Adoptive immunotherapy for cancer: building on successGene therapy with human and mouse T-cell receptors mediates cancer regression and targets normal tissues expressing cognate antigenAdoptive cell transfer: a clinical path to effective cancer immunotherapyCancer regression in patients after transfer of genetically engineered lymphocytesGenetic engineering with T cell receptorsAdoptive T-cell therapy for LeukemiaT-cell receptor gene therapy--ready to go viral?Manufacture of tumor- and virus-specific T lymphocytes for adoptive cell therapiesHow (specific) would like your T-cells today? Generating T-cell therapeutic function through TCR-gene transferCase report of a serious adverse event following the administration of T cells transduced with a chimeric antigen receptor recognizing ERBB2Lentiviral vector design for optimal T cell receptor gene expression in the transduction of peripheral blood lymphocytes and tumor-infiltrating lymphocytes.The impact of TCR-binding properties and antigen presentation format on T cell responsiveness.Relationship of p53 overexpression on cancers and recognition by anti-p53 T cell receptor-transduced T cellsA human ErbB2-specific T-cell receptor confers potent antitumor effector functions in genetically engineered primary cytotoxic lymphocytes.The human application of gene therapy to re-program T-cell specificity using chimeric antigen receptorsGenetically engineered T cells for the treatment of cancer.Development of human anti-murine T-cell receptor antibodies in both responding and nonresponding patients enrolled in TCR gene therapy trials.Improving adoptive T cell therapy by targeting and controlling IL-12 expression to the tumor environment.Treating cancer with genetically engineered T cells.Increased intensity lymphodepletion and adoptive immunotherapy--how far can we go?Cytokine-independent growth and clonal expansion of a primary human CD8+ T-cell clone following retroviral transduction with the IL-15 gene.Clinical-scale lentiviral vector transduction of PBL for TCR gene therapy and potential for expression in less-differentiated cells.Isolation of neoantigen-specific T cells from tumor and peripheral lymphocytes.Extrathymic generation of tumor-specific T cells from genetically engineered human hematopoietic stem cells via Notch signaling.Enhanced receptor expression and in vitro effector function of a murine-human hybrid MART-1-reactive T cell receptor following a rapid expansionA T-cell receptor associated with naturally occurring human tumor immunity.Enhanced antitumor activity of T cells engineered to express T-cell receptors with a second disulfide bond.Enhanced antitumor activity of murine-human hybrid T-cell receptor (TCR) in human lymphocytes is associated with improved pairing and TCR/CD3 stability.Efficient nonviral Sleeping Beauty transposon-based TCR gene transfer to peripheral blood lymphocytes confers antigen-specific antitumor reactivity.Characterization of genetically modified T-cell receptors that recognize the CEA:691-699 peptide in the context of HLA-A2.1 on human colorectal cancer cells.Gene transfer of tumor-reactive TCR confers both high avidity and tumor reactivity to nonreactive peripheral blood mononuclear cells and tumor-infiltrating lymphocytes.Adoptive cell transfer therapyAdoptive T-cell transfer in cancer immunotherapy.Effects of the tumor microenvironment on the efficacy of tumor immunotherapy.Identification of T-cell Receptors Targeting KRAS-Mutated Human Tumors.An array of possibilities in cancer research using cytokine antibody arrays.T-cell receptor gene transfer by lentiviral vectors in adoptive cell therapy.Advances and prospects in adoptive cell transfer therapy for ovarian cancerA comparison and critical analysis of preclinical anticancer vaccination strategies.Development of optimal bicistronic lentiviral vectors facilitates high-level TCR gene expression and robust tumor cell recognition
P2860
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P2860
Recognition of fresh human tumor by human peripheral blood lymphocytes transduced with a bicistronic retroviral vector encoding a murine anti-p53 TCR.
description
2005 nî lūn-bûn
@nan
2005 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Recognition of fresh human tum ...... ncoding a murine anti-p53 TCR.
@ast
Recognition of fresh human tum ...... ncoding a murine anti-p53 TCR.
@en
Recognition of fresh human tum ...... ncoding a murine anti-p53 TCR.
@nl
type
label
Recognition of fresh human tum ...... ncoding a murine anti-p53 TCR.
@ast
Recognition of fresh human tum ...... ncoding a murine anti-p53 TCR.
@en
Recognition of fresh human tum ...... ncoding a murine anti-p53 TCR.
@nl
prefLabel
Recognition of fresh human tum ...... ncoding a murine anti-p53 TCR.
@ast
Recognition of fresh human tum ...... ncoding a murine anti-p53 TCR.
@en
Recognition of fresh human tum ...... ncoding a murine anti-p53 TCR.
@nl
P2093
P2860
P1476
Recognition of fresh human tum ...... encoding a murine anti-p53 TCR
@en
P2093
Regina Bray
Richard A Morgan
Steven A Rosenberg
Yangbing Zhao
Zhili Zheng
P2860
P304
P356
10.4049/JIMMUNOL.175.9.5799
P407
P577
2005-11-01T00:00:00Z