RORγt drives production of the cytokine GM-CSF in helper T cells, which is essential for the effector phase of autoimmune neuroinflammation. - Wikidata - wikimedia - TriplyDB

RORγt drives production of the cytokine GM-CSF in helper T cells, which is essential for the effector phase of autoimmune neuroinflammation.

RORγt drives production of the cytokine GM-CSF in helper T cells, which is essential for the effector phase of autoimmune neuroinflammation.

http://www.wikidata.org/entity/Q34660473

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Modulation of autoimmune diseases by interleukin (IL)-17 producing regulatory T helper (Th17) cells Recent advances in understanding the molecular mechanisms of the development and function of Th17 cells Interactions between Autophagy and Inhibitory Cytokines The Emerging Roles of Gamma-Delta T Cells in Tissue Inflammation in Experimental Autoimmune Encephalomyelitis Th17 Cells Pathways in Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorders: Pathophysiological and Therapeutic Implications Cytokine-Defined B Cell Responses as Therapeutic Targets in Multiple Sclerosis Advances in T Helper 17 Cell Biology: Pathogenic Role and Potential Therapy in Multiple Sclerosis Th1 and Th17 Cells in Tuberculosis: Protection, Pathology, and Biomarkers Translational utility of experimental autoimmune encephalomyelitis: recent developments γδ T Cells and NK Cells - Distinct Pathogenic Roles as Innate-Like Immune Cells in CNS Autoimmunity Novel Insights and Therapeutics in Multiple Sclerosis Maintenance of Immune Homeostasis through ILC/T Cell Interactions Change of paradigm: CD8+ T cells as important helper for CD4+ T cells during asthma and autoimmune encephalomyelitis Pivotal roles of GM-CSF in autoimmunity and inflammation Vaccines for Pseudomonas aeruginosa: a long and winding road Innate immunity in the central nervous system Pouring fuel on the fire: Th17 cells, the environment, and autoimmunity Defining the functional states of Th17 cells A role for G-CSF and GM-CSF in nonmyeloid cancers An Update on PYRIN Domain-Containing Pattern Recognition Receptors: From Immunity to Pathology NF-κB in inflammation and renal diseases The dopaminergic system in autoimmune diseases Adaptive immunity to fungi NK-DC crosstalk controls the autopathogenic Th17 response through an innate IFN-γ-IL-27 axis.Lithium controls central nervous system autoimmunity through modulation of IFN-γ signaling The IL-23-IL-17 immune axis: from mechanisms to therapeutic testing NF-κB Pathways in the Pathogenesis of Multiple Sclerosis and the Therapeutic Implications Environmental factors in autoimmune diseases and their role in multiple sclerosis GM-CSF: An immune modulatory cytokine that can suppress autoimmunity T Helper Lymphocyte Subsets and Plasticity in Autoimmunity and Cancer: An Overview Role of the immunogenic and tolerogenic subsets of dendritic cells in multiple sclerosis Multiple Sclerosis and T Lymphocytes: An Entangled Story Laquinimod, a quinoline-3-carboxamide, induces type II myeloid cells that modulate central nervous system autoimmunity Sphingosine 1 Phosphate at the Blood Brain Barrier: Can the Modulation of S1P Receptor 1 Influence the Response of Endothelial Cells and Astrocytes to Inflammatory Stimuli?A validated regulatory network for Th17 cell specification Colony-stimulating factor (CSF) 1 receptor blockade reduces inflammation in human and murine models of rheumatoid arthritis Marking and quantifying IL-17A-producing cells in vivo MicroRNA-21 promotes Th17 differentiation and mediates experimental autoimmune encephalomyelitis Protective and pathogenic functions of macrophage subsets The role of dendritic cells in autoimmunity

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RORγt drives production of the cytokine GM-CSF in helper T cells, which is essential for the effector phase of autoimmune neuroinflammation.

http://www.wikidata.org/entity/Q34660473

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2011 nî lūn-bûn

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2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2011 թվականի ապրիլին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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RORγt drives production of the ...... autoimmune neuroinflammation.

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Nature Immunology

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RORγt drives production of the ...... f autoimmune neuroinflammation

@en

P2093

Adriano Fontana

http://www.w3.org/2001/XMLSchema#string

Burkhard Becher

http://www.w3.org/2001/XMLSchema#string

Gabor Gyülvészi

http://www.w3.org/2001/XMLSchema#string

Laura Codarri

http://www.w3.org/2001/XMLSchema#string

Laurent Magnenat

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Lysann Hesske

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Vinko Tosevski

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P2860

Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12

Granulocyte/macrophage colony-stimulating factor-deficient mice show no major perturbation of hematopoiesis but develop a characteristic pulmonary pathology

The interleukin 23 receptor is essential for the terminal differentiation of interleukin 17-producing effector T helper cells in vivo

Generation of pathogenic T(H)17 cells in the absence of TGF-β signalling

APC-derived cytokines and T cell polarization in autoimmune inflammation

Th17 and regulatory T cells in mediating and restraining inflammation.

Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells

Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17

IL-23: changing the verdict on IL-12 function in inflammation and autoimmunity

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560-567

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scholarly article

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10.1038/NI.2027

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6

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12

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51073137

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21516112

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