about
The MLL fusion gene, MLL-AF4, regulates cyclin-dependent kinase inhibitor CDKN1B (p27kip1) expressionHoxa9 and Meis1 are key targets for MLL-ENL-mediated cellular immortalizationDifferential and common leukemogenic potentials of multiple NUP98-Hox fusion proteins alone or with Meis1The homeobox gene CDX2 is aberrantly expressed in most cases of acute myeloid leukemia and promotes leukemogenesisLinking Pesticide Exposure with Pediatric Leukemia: Potential Underlying MechanismsAcute Myeloid Leukemia: A Concise ReviewMolecular prognostic factors in cytogenetically normal acute myeloid leukemiaNovel Prognostic and Therapeutic Mutations in Acute Myeloid LeukemiaFunctional contribution of EEN to leukemogenic transformation by MLL-EEN fusion proteinADAR1 is required for hematopoietic progenitor cell survival via RNA editingMenin-MLL inhibitors reverse oncogenic activity of MLL fusion proteins in leukemiaThe homeobox gene Hhex regulates the earliest stages of definitive hematopoiesis.Genetic abnormalities and challenges in the treatment of acute myeloid leukemia.PQJS380: a novel lead compound to induce apoptosis in acute lymphoblastic leukemia cellsMLL 5 protein forms intranuclear foci, and overexpression inhibits cell cycle progressionPharmacologic inhibition of the Menin-MLL interaction blocks progression of MLL leukemia in vivo.Malignant hematopoietic cell lines: in vitro models for the study of MLL gene alterations.Linking the epigenetic 'language' of covalent histone modifications to cancer.MLL fusions: pathways to leukemiaThe MLL partial tandem duplication: evidence for recessive gain-of-function in acute myeloid leukemia identifies a novel patient subgroup for molecular-targeted therapyC/EBPbeta suppression by interruption of CUGBP1 resulting from a complex rearrangement of MLL.The biological and clinical significance of MLL abnormalities in haematological malignancies.CCI-007, a novel small molecule with cytotoxic activity against infant leukemia with MLL rearrangements.Predicting the effect of transcription therapy in hematologic malignancies.Molecular genetic analysis of haematological malignancies: I. Acute leukaemias and myeloproliferative disorders.Hox genes: from leukemia to hematopoietic stem cell expansion.Successful Administration of Recombinant Human Soluble Thrombomodulin α (Recomodulin) for Disseminated Intravascular Coagulation during Induction Chemotherapy in an Elderly Patient with Acute Monoblastic Leukemia Involving the t(9;11)(p22;q23) MLL/ARNA-mediated gene silencing in hematopoietic cells.Epigenetic regulation of normal and malignant hematopoiesis.RAS oncogene suppression induces apoptosis followed by more differentiated and less myelosuppressive disease upon relapse of acute myeloid leukemia.Menin, histone h3 methyltransferases, and regulation of cell proliferation: current knowledge and perspective.Conquering the complex world of human septins: implications for health and disease.MLL-SEPT5 fusion transcript in infant acute myeloid leukemia with t(11;22)(q23;q11).New insights into MLL gene rearranged acute leukemias using gene expression profiling: shared pathways, lineage commitment, and partner genes.Chemical exposure and infant leukaemia: development of an adverse outcome pathway (AOP) for aetiology and risk assessment research.Chlorpyrifos Induces MLL Translocations Through Caspase 3-Dependent Genomic Instability and Topoisomerase II Inhibition in Human Fetal Liver Hematopoietic Stem Cells.Zinc Finger Nuclease induced DNA double stranded breaks and rearrangements in MLL.Acute myeloid leukaemia genomics.Direct physical and functional interaction of the NuA4 complex components Yaf9p and Swc4p.Notch signaling is a potent inducer of growth arrest and apoptosis in a wide range of B-cell malignancies.
P2860
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P2860
description
2002 nî lūn-bûn
@nan
2002 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
The role of MLL in hematopoiesis and leukemia.
@ast
The role of MLL in hematopoiesis and leukemia.
@en
The role of MLL in hematopoiesis and leukemia.
@nl
type
label
The role of MLL in hematopoiesis and leukemia.
@ast
The role of MLL in hematopoiesis and leukemia.
@en
The role of MLL in hematopoiesis and leukemia.
@nl
prefLabel
The role of MLL in hematopoiesis and leukemia.
@ast
The role of MLL in hematopoiesis and leukemia.
@en
The role of MLL in hematopoiesis and leukemia.
@nl
P2093
P1476
The role of MLL in hematopoiesis and leukemia.
@en
P2093
Patricia Ernst
Stanley J Korsmeyer
P304
P356
10.1097/00062752-200207000-00004
P577
2002-07-01T00:00:00Z