Ubiquitination of mammalian Pex5p, the peroxisomal import receptor.
about
Members of the E2D (UbcH5) family mediate the ubiquitination of the conserved cysteine of Pex5p, the peroxisomal import receptorPEX5 protein binds monomeric catalase blocking its tetramerization and releases it upon binding the N-terminal domain of PEX14HECT and RING finger families of E3 ubiquitin ligases at a glanceThe ubiquitin-conjugating enzyme (E2) Ube2w ubiquitinates the N terminus of substratesPeroxisome biogenesis in mammalian cellsPlant peroxisomes: biogenesis and functionATM functions at the peroxisome to induce pexophagy in response to ROS.A disulphide bond in the E2 enzyme Pex4p modulates ubiquitin-conjugating activityThe predator becomes the prey: regulating the ubiquitin system by ubiquitylation and degradationPex2 and pex12 function as protein-ubiquitin ligases in peroxisomal protein import.Distinct ubiquitination cascades act on the peroxisomal targeting signal type 2 co-receptor Pex18p.The cytosolic domain of Pex22p stimulates the Pex4p-dependent ubiquitination of the PTS1-receptor.Ubp15p, a ubiquitin hydrolase associated with the peroxisomal export machinery.Degradation-mediated protein quality control at the inner nuclear membraneAWP1/ZFAND6 functions in Pex5 export by interacting with cys-monoubiquitinated Pex5 and Pex6 AAA ATPaseThe peroxisome: still a mysterious organelleProperties of the ubiquitin-pex5p thiol ester conjugate.Cysteine ubiquitination of PTS1 receptor Pex5p regulates Pex5p recycling.Ube2j2 ubiquitinates hydroxylated amino acids on ER-associated degradation substrates.Serine residues in the cytosolic tail of the T-cell antigen receptor alpha-chain mediate ubiquitination and endoplasmic reticulum-associated degradation of the unassembled protein.High-yield expression in Escherichia coli and purification of mouse ubiquitin-activating enzyme E1.A PEX7-centered perspective on the peroxisomal targeting signal type 2-mediated protein import pathway.Complex regulation controls Neurogenin3 proteolysis.Ubiquitylation on canonical and non-canonical sites targets the transcription factor neurogenin for ubiquitin-mediated proteolysisThe peroxisomal protein import machinery displays a preference for monomeric substrates.Peroxisome biogenesis and function.Revisiting the intraperoxisomal pathway of mammalian PEX7.Identification of ubiquitin-specific protease 9X (USP9X) as a deubiquitinase acting on ubiquitin-peroxin 5 (PEX5) thioester conjugate.Export-deficient monoubiquitinated PEX5 triggers peroxisome removal in SV40 large T antigen-transformed mouse embryonic fibroblasts.Cysteine-specific ubiquitination protects the peroxisomal import receptor Pex5p against proteasomal degradationThe ubiquitin-proteasome system of Saccharomyces cerevisiae.Covalent Label Transfer between Peroxisomal Importomer Components Reveals Export-driven Import InteractionsA cargo-centered perspective on the PEX5 receptor-mediated peroxisomal protein import pathway.Shuttles and cycles: transport of proteins into the peroxisome matrix (review).Mapping the cargo protein membrane translocation step into the PEX5 cycling pathway.Protein transport across the peroxisomal membrane.Peroxisome biogenesis and human peroxisome-deficiency disorders.Getting a camel through the eye of a needle: the import of folded proteins by peroxisomes.Making new out of old: recycling and modification of an ancient protein translocation system during eukaryotic evolution. Mechanistic comparison and phylogenetic analysis of ERAD, SELMA and the peroxisomal importomer.Ubiquitination of substrates by esterification.
P2860
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P2860
Ubiquitination of mammalian Pex5p, the peroxisomal import receptor.
description
2007 nî lūn-bûn
@nan
2007 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Ubiquitination of mammalian Pex5p, the peroxisomal import receptor.
@ast
Ubiquitination of mammalian Pex5p, the peroxisomal import receptor.
@en
Ubiquitination of mammalian Pex5p, the peroxisomal import receptor.
@nl
type
label
Ubiquitination of mammalian Pex5p, the peroxisomal import receptor.
@ast
Ubiquitination of mammalian Pex5p, the peroxisomal import receptor.
@en
Ubiquitination of mammalian Pex5p, the peroxisomal import receptor.
@nl
prefLabel
Ubiquitination of mammalian Pex5p, the peroxisomal import receptor.
@ast
Ubiquitination of mammalian Pex5p, the peroxisomal import receptor.
@en
Ubiquitination of mammalian Pex5p, the peroxisomal import receptor.
@nl
P2093
P2860
P50
P356
P1476
Ubiquitination of mammalian Pex5p, the peroxisomal import receptor
@en
P2093
Andreia F Carvalho
Clara Sá-Miranda
Cláudia P Grou
Inês S Alencastre
Manuel P Pinto
Marc Fransen
P2860
P304
31267-31272
P356
10.1074/JBC.M706325200
P407
P50
P577
2007-08-28T00:00:00Z