A novel T cell receptor single-chain signaling complex mediates antigen-specific T cell activity and tumor control
about
Recent advances in T-cell engineering for use in immunotherapyTCR affinity for p/MHC formed by tumor antigens that are self-proteins: impact on efficacy and toxicityStrategies to genetically engineer T cells for cancer immunotherapy.Deletion with 25 nucleotides of TCRζ gene in T cells from a case with chronic myeloid leukemiaAn Engineered Switch in T Cell Receptor Specificity Leads to an Unusual but Functional Binding Geometry.An optimized single chain TCR scaffold relying on the assembly with the native CD3-complex prevents residual mispairing with endogenous TCRs in human T-cells.Adoptive T Cell Therapies: A Comparison of T Cell Receptors and Chimeric Antigen ReceptorsImmunotherapy for advanced melanoma: future directions.Tumor-targeting domains for chimeric antigen receptor T cells.Therapeutic T cell engineering.Comparison of T Cell Activities Mediated by Human TCRs and CARs That Use the Same Recognition Domains.A CD200R-CD28 fusion protein appropriates an inhibitory signal to enhance T-cell function and therapy of murine leukemia.TCR modifications that enhance chain pairing in gene-modified T cells can augment cross-reactivity and alleviate CD8 dependence.An MHC-restricted antibody-based chimeric antigen receptor requires TCR-like affinity to maintain antigen specificity.
P2860
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P2860
A novel T cell receptor single-chain signaling complex mediates antigen-specific T cell activity and tumor control
description
2014 nî lūn-bûn
@nan
2014 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
A novel T cell receptor single ...... ell activity and tumor control
@ast
A novel T cell receptor single ...... ell activity and tumor control
@en
A novel T cell receptor single ...... ell activity and tumor control
@nl
type
label
A novel T cell receptor single ...... ell activity and tumor control
@ast
A novel T cell receptor single ...... ell activity and tumor control
@en
A novel T cell receptor single ...... ell activity and tumor control
@nl
prefLabel
A novel T cell receptor single ...... ell activity and tumor control
@ast
A novel T cell receptor single ...... ell activity and tumor control
@en
A novel T cell receptor single ...... ell activity and tumor control
@nl
P2093
P2860
P1476
A novel T cell receptor single ...... ell activity and tumor control
@en
P2093
Adam S Chervin
Carolina M Soto
Daniel T Harris
David M Kranz
Edward J Roy
Jennifer D Stone
P2860
P2888
P304
P356
10.1007/S00262-014-1586-Z
P577
2014-08-01T00:00:00Z
P6179
1043843785