Spatial heterogeneity of endothelial phenotypes correlates with side-specific vulnerability to calcification in normal porcine aortic valves.
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Large animal models of cardiovascular diseaseFibrocalcific aortic valve disease: opportunity to understand disease mechanisms using mouse modelsIn vitro models of aortic valve calcification: solidifying a systemMolecular and cellular aspects of calcific aortic valve diseasePulling on my heartstrings: mechanotransduction in cardiac development and functionThe heterogeneous biomechanics and mechanobiology of the mitral valve: implications for tissue engineering.Calcific aortic valve stenosis: methods, models, and mechanismsEx vivo evidence for the contribution of hemodynamic shear stress abnormalities to the early pathogenesis of calcific bicuspid aortic valve disease.Cofilin is a marker of myofibroblast differentiation in cells from porcine aortic cardiac valves.A computational model of aging and calcification in the aortic heart valveMechano-potential etiologies of aortic valve diseaseAortic valve: mechanical environment and mechanobiology.Altered shear stress stimulates upregulation of endothelial VCAM-1 and ICAM-1 in a BMP-4- and TGF-beta1-dependent pathwayPreferential activation of SMAD1/5/8 on the fibrosa endothelium in calcified human aortic valves--association with low BMP antagonists and SMAD6Elevated cyclic stretch induces aortic valve calcification in a bone morphogenic protein-dependent mannerDrug-induced valvulopathy: an update.Effects of disturbed flow on vascular endothelium: pathophysiological basis and clinical perspectivesSerotonin receptors and heart valve disease--it was meant 2B.Potential drug targets for calcific aortic valve disease.Endothelial protein kinase C isoform identity and differential activity of PKCzeta in an athero-susceptible region of porcine aorta.Tie1 attenuation reduces murine atherosclerosis in a dose-dependent and shear stress-specific mannerDirecting valvular interstitial cell myofibroblast-like differentiation in a hybrid hydrogel platform.Scanning ion conductance microscopy: a convergent high-resolution technology for multi-parametric analysis of living cardiovascular cellsDefining the role of fluid shear stress in the expression of early signaling markers for calcific aortic valve disease.Networked-based characterization of extracellular matrix proteins from adult mouse pulmonary and aortic valves.Inflammatory regulation of valvular remodeling: the good(?), the bad, and the ugly.Animal models of calcific aortic valve diseaseSide-specific mechanical properties of valve endothelial cells.An ex vivo study of the biological properties of porcine aortic valves in response to circumferential cyclic stretch.Discovery of shear- and side-specific mRNAs and miRNAs in human aortic valvular endothelial cells.Endothelial-derived oxidative stress drives myofibroblastic activation and calcification of the aortic valveCalcific aortic valve disease: not simply a degenerative process: A review and agenda for research from the National Heart and Lung and Blood Institute Aortic Stenosis Working Group. Executive summary: Calcific aortic valve disease-2011 update.Age-Dependent Changes in Geometry, Tissue Composition and Mechanical Properties of Fetal to Adult Cryopreserved Human Heart ValvesPathological Investigation of Congenital Bicuspid Aortic Valve Stenosis, Compared with Atherosclerotic Tricuspid Aortic Valve Stenosis and Congenital Bicuspid Aortic Valve Regurgitation.Thematic review series: The immune system and atherogenesis. Cytokines affecting endothelial and smooth muscle cells in vascular disease.Osteopontin controls endothelial cell migration in vitro and in excised human valvular tissue from patients with calcific aortic stenosis and controls.Pioglitazone attenuates valvular calcification induced by hypercholesterolemia.Heart valve tissue engineering: concepts, approaches, progress, and challenges.Calcific Aortic Valve Disease: Part 1--Molecular Pathogenetic Aspects, Hemodynamics, and Adaptive Feedbacks.Side-specific endothelial-dependent regulation of aortic valve calcification: interplay of hemodynamics and nitric oxide signaling.
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P2860
Spatial heterogeneity of endothelial phenotypes correlates with side-specific vulnerability to calcification in normal porcine aortic valves.
description
2005 nî lūn-bûn
@nan
2005 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի մարտին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Spatial heterogeneity of endot ...... normal porcine aortic valves.
@ast
Spatial heterogeneity of endot ...... normal porcine aortic valves.
@en
Spatial heterogeneity of endot ...... normal porcine aortic valves.
@nl
type
label
Spatial heterogeneity of endot ...... normal porcine aortic valves.
@ast
Spatial heterogeneity of endot ...... normal porcine aortic valves.
@en
Spatial heterogeneity of endot ...... normal porcine aortic valves.
@nl
prefLabel
Spatial heterogeneity of endot ...... normal porcine aortic valves.
@ast
Spatial heterogeneity of endot ...... normal porcine aortic valves.
@en
Spatial heterogeneity of endot ...... normal porcine aortic valves.
@nl
P2860
P1433
P1476
Spatial heterogeneity of endot ...... n normal porcine aortic valves
@en
P2093
Craig A Simmons
Peter F Davies
P2860
P304
P356
10.1161/01.RES.0000161998.92009.64
P577
2005-03-10T00:00:00Z