Interferon-inducible mechanism of dendritic cell-mediated HIV-1 dissemination is dependent on Siglec-1/CD169.
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Blocking HIV-1 transmission in the female reproductive tract: from microbicide development to exploring local antiviral responsesExosomes: Implications in HIV-1 PathogenesisCD169-dependent cell-associated HIV-1 transmission: a driver of virus disseminationDressing up Nanoparticles: A Membrane Wrap to Induce Formation of the Virological Synapse.CD169-mediated trafficking of HIV to plasma membrane invaginations in dendritic cells attenuates efficacy of anti-gp120 broadly neutralizing antibodiesPolyICLC Exerts Pro- and Anti-HIV Effects on the DC-T Cell Milieu In Vitro and In VivoRetroviruses use CD169-mediated trans-infection of permissive lymphocytes to establish infection.Possible functions of CD169-positive sinus macrophages in lymph nodes in anti-tumor immune responsesGlycosphingolipid-functionalized nanoparticles recapitulate CD169-dependent HIV-1 uptake and trafficking in dendritic cellsVirus particle release from glycosphingolipid-enriched microdomains is essential for dendritic cell-mediated capture and transfer of HIV-1 and henipavirus.The interplay between Siglecs and sialylated pathogensSiglec-mediated regulation of immune cell function in disease.HIV-1 immune activation induces Siglec-1 expression and enhances viral trans-infection in blood and tissue myeloid cells.Strategies for preventing mucosal cell-associated HIV transmission.Modeling mucosal cell-associated HIV type 1 transmission in vitro.HIV-1 capture and transmission by dendritic cells: the role of viral glycolipids and the cellular receptor Siglec-1Quantifying lipid contents in enveloped virus particles with plasmonic nanoparticlesIFITM Proteins Restrict HIV-1 Infection by Antagonizing the Envelope Glycoprotein.Siglec-1 initiates formation of the virus-containing compartment and enhances macrophage-to-T cell transmission of HIV-1.Mucosal stromal fibroblasts markedly enhance HIV infection of CD4+ T cells.Mouse Siglec-1 Mediates trans-Infection of Surface-bound Murine Leukemia Virus in a Sialic Acid N-Acyl Side Chain-dependent Manner.Lipid-Mediated Targeting with Membrane-Wrapped Nanoparticles in the Presence of Corona FormationAntiretroviral therapy in HIV-1-infected individuals with CD4 count below 100 cells/mm3 results in differential recovery of monocyte activation.Effect of cytokines on Siglec-1 and HIV-1 entry in monocyte-derived macrophages: the importance of HIV-1 envelope V1V2 regionIdentification of Siglec-1 null individuals infected with HIV-1.Cell-Free versus Cell-to-Cell Infection by Human Immunodeficiency Virus Type 1 and Human T-Lymphotropic Virus Type 1: Exploring the Link among Viral Source, Viral Trafficking, and Viral Replication.Neutralizing IgG at the portal of infection mediates protection against vaginal simian/human immunodeficiency virus challengeHost Immune Responses in HIV-1 Infection: The Emerging Pathogenic Role of Siglecs and Their Clinical Correlates.DC-T cell virological synapses and the skin: novel perspectives in dermatology.A mechanistic overview of dendritic cell-mediated HIV-1 trans infection: the story so far.Therapeutic Targeting of Siglecs using Antibody- and Glycan-Based Approaches.Access of HIV-2 to CD169-dependent dendritic cell-mediated trans infection pathway is attenuated.Trans-dissemination of exosomes from HIV-1-infected cells fosters both HIV-1 trans-infection in resting CD4(+) T lymphocytes and reactivation of the HIV-1 reservoir.Viruses exploit the tissue physiology of the host to spread in vivo.Metabolic Glycoengineering with N-Acyl Side Chain Modified Mannosamines.Metabolic sialic acid blockade lowers the activation threshold of moDCs for TLR stimulation.HIV Fusion in Dendritic Cells Occurs Mainly at the Surface and Is Limited by Low CD4 Levels.Interferon-Inducible CD169/Siglec1 Attenuates Anti-HIV-1 Effects of Alpha Interferon.Virion-Associated Vpr Alleviates a Postintegration Block to HIV-1 Infection of Dendritic Cells.The role of Siglec-1 in HIV-1/macrophage interaction.
P2860
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P2860
Interferon-inducible mechanism of dendritic cell-mediated HIV-1 dissemination is dependent on Siglec-1/CD169.
description
2013 nî lūn-bûn
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2013 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Interferon-inducible mechanism ...... s dependent on Siglec-1/CD169.
@ast
Interferon-inducible mechanism ...... s dependent on Siglec-1/CD169.
@en
Interferon-inducible mechanism ...... s dependent on Siglec-1/CD169.
@nl
type
label
Interferon-inducible mechanism ...... s dependent on Siglec-1/CD169.
@ast
Interferon-inducible mechanism ...... s dependent on Siglec-1/CD169.
@en
Interferon-inducible mechanism ...... s dependent on Siglec-1/CD169.
@nl
prefLabel
Interferon-inducible mechanism ...... s dependent on Siglec-1/CD169.
@ast
Interferon-inducible mechanism ...... s dependent on Siglec-1/CD169.
@en
Interferon-inducible mechanism ...... s dependent on Siglec-1/CD169.
@nl
P2093
P2860
P1433
P1476
Interferon-inducible mechanism ...... s dependent on Siglec-1/CD169.
@en
P2093
Björn M Reinhard
Hisashi Akiyama
Nora P Ramirez
Wendy Blay Puryear
P2860
P304
P356
10.1371/JOURNAL.PPAT.1003291
P577
2013-04-11T00:00:00Z