Yeast dihydroorotate dehydrogenase as a new selectable marker for Plasmodium falciparum transfection.
about
Structure-Guided Lead Optimization of Triazolopyrimidine-Ring Substituents Identifies Potent Plasmodium falciparum Dihydroorotate Dehydrogenase Inhibitors with Clinical Candidate PotentialA triazolopyrimidine-based dihydroorotate dehydrogenase inhibitor (DSM421) with improved drug-like properties for treatment and prevention of malariaImaging of Plasmodium Liver Stages to Drive Next-Generation Antimalarial Drug DiscoveryKinase-associated endopeptidase 1 (Kae1) participates in an atypical ribosome-associated complex in the apicoplast of Plasmodium falciparumDeconvoluting heme biosynthesis to target blood-stage malaria parasitesDirect tests of enzymatic heme degradation by the malaria parasite Plasmodium falciparumMitochondrial RNA polymerase is an essential enzyme in erythrocytic stages of Plasmodium falciparumATP synthase complex of Plasmodium falciparum: dimeric assembly in mitochondrial membranes and resistance to genetic disruptionEvidence for a Golgi-to-endosome protein sorting pathway in Plasmodium falciparumTowards genome-wide experimental genetics in the in vivo malaria model parasite Plasmodium bergheiIdentification of inhibitors that dually target the new permeability pathway and dihydroorotate dehydrogenase in the blood stage of Plasmodium falciparumPlasmodium falciparum heat shock protein 110 stabilizes the asparagine repeat-rich parasite proteome during malarial feversDNA repair mechanisms and their biological roles in the malaria parasite Plasmodium falciparum.Lead optimization of aryl and aralkyl amine-based triazolopyrimidine inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase with antimalarial activity in miceVariation among Plasmodium falciparum strains in their reliance on mitochondrial electron transport chain functionArrested oocyst maturation in Plasmodium parasites lacking type II NADH:ubiquinone dehydrogenase.Inhibition of cytochrome bc1 as a strategy for single-dose, multi-stage antimalarial therapyA redesigned CRISPR/Cas9 system for marker-free genome editing in Plasmodium falciparum.Tetrahydro-2-naphthyl and 2-Indanyl Triazolopyrimidines Targeting Plasmodium falciparum Dihydroorotate Dehydrogenase Display Potent and Selective Antimalarial ActivityBiochemical and molecular characterization of the pyrimidine biosynthetic enzyme dihydroorotate dehydrogenase from Toxoplasma gondiiMalaria parasites utilize both homologous recombination and alternative end joining pathways to maintain genome integrity.A molecular switch in the efficiency of translation reinitiation controls expression of var2csa, a gene implicated in pregnancy-associated malaria.Functional genetics in Apicomplexa: potentials and limits.From the genome to the phenome: tools to understand the basic biology of Plasmodium falciparum.The Exported Chaperone PfHsp70x Is Dispensable for the Plasmodium falciparum Intraerythrocytic Life Cycle.Exploitation of a newly-identified entry pathway into the malaria parasite-infected erythrocyte to inhibit parasite egress.Genome editing in the human malaria parasite Plasmodium falciparum using the CRISPR-Cas9 system.Host biotin is required for liver stage development in malaria parasites.Establishment of a stable transfection system for genetic manipulation of Babesia gibsoni.EXP2 is a nutrient-permeable channel in the vacuolar membrane of Plasmodium and is essential for protein export via PTEXIsoxazolopyrimidine-Based Inhibitors of Dihydroorotate Dehydrogenase with Antimalarial Activity
P2860
Q27670499-0A434D08-1D71-4A34-887D-0316CDA7D36FQ27728080-960379BE-30A9-4AF5-BE6F-27108FF4086CQ27861956-AE30D0F4-166C-47E0-AC54-D6D25F1DC89AQ27972867-65EA8EB1-ABA7-4F10-9D90-8848354FF3B8Q27973107-0CCF0E00-90C4-44C0-BC3A-5FF96BD5A500Q27973434-872E3CAF-0B4C-4FB6-8052-071FE8C81B50Q27973464-71AB5F97-41DA-482E-8399-D4505334B438Q27973781-61732755-970B-4B72-A334-8AE2B9EEE240Q27974240-EEAEE7A3-B77B-4E5B-8F8D-6BD0B153B2D6Q28084219-79E3B441-F26F-407D-91E9-14802622E4B3Q30041617-C52E3D18-CA42-43E3-9641-DCCE7A782FADQ30042023-1BF09A9A-5F99-4678-8B2B-592C6FB5D043Q34297803-75B09B5E-14C9-4B70-8B61-974F54638F4CQ35071496-FB99563E-D887-435B-B72B-C8E25884D6FEQ35191792-0A506C99-49BC-41BC-BAF4-8EBFE81C16DDQ35213449-73802E1F-9AC2-478D-8476-E5533135C622Q35692516-2F876663-FC87-48AA-B24E-D2D015B628A1Q36790532-54B4BD22-7A14-4797-82DB-74CB117AD2B2Q36996257-822A3579-8E57-45E9-AA05-83116B0777DBQ37374814-898BCA45-58A1-4C10-B14A-987AAC69906DQ37417056-D7B6FE65-E308-4184-B4B6-8D42005F1AACQ37610154-396E1124-9B86-49AF-8BA3-3238D5FBFDF7Q37873986-A98BBEA5-6F11-4478-A796-1E31A710B5ABQ38250222-44378811-40F2-4CC7-BED1-50B10DD53342Q41676484-EFA206DE-3302-46D3-B9DA-B793612B4BCEQ41994264-EF53CBD3-B3B2-4908-A60A-CCBAC55C2EC3Q47868849-AF105468-30B0-473C-BF35-2737F5E4F020Q50421800-876ED1AA-E4F5-4302-BD28-AC8028E60D54Q52569145-C7FAA20D-37A2-4378-BA5F-0DEE684A27B5Q56305756-06F83BEF-0B0A-4497-B3CA-E34A9F55943CQ58776522-DEA71A37-F211-43A8-82BD-A2E86C6B6A05
P2860
Yeast dihydroorotate dehydrogenase as a new selectable marker for Plasmodium falciparum transfection.
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Yeast dihydroorotate dehydroge ...... odium falciparum transfection.
@ast
Yeast dihydroorotate dehydroge ...... odium falciparum transfection.
@en
Yeast dihydroorotate dehydroge ...... odium falciparum transfection.
@nl
type
label
Yeast dihydroorotate dehydroge ...... odium falciparum transfection.
@ast
Yeast dihydroorotate dehydroge ...... odium falciparum transfection.
@en
Yeast dihydroorotate dehydroge ...... odium falciparum transfection.
@nl
prefLabel
Yeast dihydroorotate dehydroge ...... odium falciparum transfection.
@ast
Yeast dihydroorotate dehydroge ...... odium falciparum transfection.
@en
Yeast dihydroorotate dehydroge ...... odium falciparum transfection.
@nl
P2093
P2860
P1476
Yeast dihydroorotate dehydroge ...... modium falciparum transfection
@en
P2093
Akhil B Vaidya
Hangjun Ke
Heather J Painter
Joanne M Morrisey
Kamal Laroiya
Margaret A Phillips
Pradipsinh K Rathod
Suresh M Ganesan
P2860
P356
10.1016/J.MOLBIOPARA.2011.01.004
P577
2011-01-18T00:00:00Z