Pharmacological strategies to increase the antitumor activity of methylating agents.
about
The combination of BH3-mimetic ABT-737 with the alkylating agent temozolomide induces strong synergistic killing of melanoma cells independent of p53Dose finding and O6-alkylguanine-DNA alkyltransferase study of cisplatin combined with temozolomide in paediatric solid malignancies.DNA ligase IV as a new molecular target for temozolomidePotentiation of temozolomide cytotoxicity by inhibition of DNA polymerase beta is accentuated by BRCA2 mutation.Effect of n3-methyladenine and an isosteric stable analogue on DNA polymerization.3-Methyl-3-deazaadenine, a stable isostere of N3-methyl-adenine, is efficiently bypassed by replication in vivo and by transcription in vitro.N-methylpurine DNA glycosylase inhibits p53-mediated cell cycle arrest and coordinates with p53 to determine sensitivity to alkylating agents.Downregulation of hPMC2 imparts chemotherapeutic sensitivity to alkylating agents in breast cancer cellsOncolytic viruses and DNA-repair machinery: overcoming chemoresistance of gliomas.Propolis changes the anticancer activity of temozolomide in U87MG human glioblastoma cell lineProspective study evaluating the radiosensitizing effect of reduced doses of temozolomide in the treatment of Egyptian patients with glioblastoma multiformeNew (alternative) temozolomide regimens for the treatment of glioma.Mutagenicity of N3-methyladenine: a multi-translesion polymerase affair.Towards tailored therapy of glioblastoma multiforme.Methoxyamine sensitizes the resistant glioblastoma T98G cell line to the alkylating agent temozolomide.Thermodynamic characterization of DNA with 3-deazaadenine and 3-methyl-3-deazaadenine substitutions: the effect of placing a hydrophobic group in the minor groove of DNA.Replication of the 2,6-diamino-4-hydroxy-N(5)-(methyl)-formamidopyrimidine (MeFapy-dGuo) adduct by eukaryotic DNA polymerases.The Alkylating Chemotherapeutic Temozolomide Induces Metabolic Stress in IDH1-Mutant Cancers and Potentiates NAD+ Depletion-Mediated Cytotoxicity.A phase IB trial of intravenous INO-1001 plus oral temozolomide in subjects with unresectable stage-III or IV melanoma.Successful Second-Line Metronomic Temozolomide in Metastatic Paraganglioma: Case Reports and Review of the Literature.PAXX Participates in Base Excision Repair via Interacting with Pol β and Contributes to TMZ Resistance in Glioma Cells
P2860
Q28476737-AA2DC25B-73F8-47C9-ACF9-C07258B7D3D3Q33368246-9031A980-4FDB-425A-BE17-9153153FF8FFQ33699997-15CCB543-A2E0-4EDB-B4B2-B46F6C3B778CQ34146866-0FCDD711-9977-4938-92B6-0DB7749F3516Q34155773-873890EC-F871-4D95-A011-602FBE69AE41Q35136570-48FC97E5-4336-41B0-82C6-0B6F8A445BE6Q36137812-F88AB788-923F-40C5-9219-4BFB74E066F1Q36214603-2A9F38B0-0F2F-4D93-9163-53B3B3D8D488Q36668242-A4B9F52B-CB68-4006-8F5E-2BC5E4556D85Q36687919-FC87D402-8770-456F-B4CB-F62EF32A963AQ37231076-CBC8AC7D-B856-4A86-9D6A-D4BC8861469CQ37261125-C30AD209-149C-4A20-9881-8ECBE40A6845Q37479968-2830C69D-425E-46CE-BAE1-2713725B0E81Q37908815-44D8439C-161B-46DF-B6EC-F0CF6D6ACBECQ39308847-7CCBC51F-BB67-488E-AFF0-0D568B8F8CBAQ40879843-97C2ED5D-2066-4542-9441-6F5889416BE9Q42092883-16D6EFA0-1EA8-47FC-A93C-13AF079319C3Q42511174-AEEFCABF-EBCE-43CA-9D96-8015E6A64553Q46013098-C6749B11-B622-4D1E-AD61-41A49ACC4DEAQ55332110-B1AC0D0E-9742-4427-A1C9-03E263AE812BQ58709371-72F48F5B-79B7-47C3-B630-5871272C4D64
P2860
Pharmacological strategies to increase the antitumor activity of methylating agents.
description
2002 nî lūn-bûn
@nan
2002 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Pharmacological strategies to increase the antitumor activity of methylating agents.
@ast
Pharmacological strategies to increase the antitumor activity of methylating agents.
@en
Pharmacological strategies to increase the antitumor activity of methylating agents.
@nl
type
label
Pharmacological strategies to increase the antitumor activity of methylating agents.
@ast
Pharmacological strategies to increase the antitumor activity of methylating agents.
@en
Pharmacological strategies to increase the antitumor activity of methylating agents.
@nl
prefLabel
Pharmacological strategies to increase the antitumor activity of methylating agents.
@ast
Pharmacological strategies to increase the antitumor activity of methylating agents.
@en
Pharmacological strategies to increase the antitumor activity of methylating agents.
@nl
P356
P1476
Pharmacological strategies to increase the antitumor activity of methylating agents.
@en
P2093
Grazia Graziani
Lucio Tentori
P304
P356
10.2174/0929867023369916
P577
2002-07-01T00:00:00Z