A new bispecific antibody targeting non-overlapping epitopes on IGF2: design, in vitro characterization and pharmacokinetics in macaques
about
A dual-specific anti-IGF-1/IGF-2 human monoclonal antibody alone and in combination with temsirolimus for therapy of neuroblastoma.Insulin-like growth factor 2 axis supports the serum-independent growth of malignant rhabdoid tumor and is activated by microenvironment stress.Targeted Fcγ Receptor (FcγR)-mediated Clearance by a Biparatopic Bispecific AntibodyA native-like bispecific antibody suppresses the inflammatory cytokine response by simultaneously neutralizing tumor necrosis factor-alpha and interleukin-17A.Tandem phage-display for the identification of non-overlapping binding pairs of recombinant affinity reagents.A dual-specific IGF-I/II human engineered antibody domain inhibits IGF signaling in breast cancer cells.Expanding the Boundaries of Biotherapeutics with Bispecific Antibodies
P2860
Q37162205-899D0576-9FF3-4BBA-BAEC-D4DF04A86D20Q38682244-EFBBD269-BEBF-4047-97F9-E082930D225CQ40366353-1064DB6C-ADC4-40F6-AC22-231A2A1765E1Q47102100-A57CE50C-99AF-4E79-A430-DB26FE518167Q47686932-B51E231D-79AF-4A85-99FF-A2954DAC0507Q55128069-2F1A73C0-647E-4C37-9CBD-890231531B57Q58724935-55889231-622D-4357-B1B4-2D8F3EFFE81B
P2860
A new bispecific antibody targeting non-overlapping epitopes on IGF2: design, in vitro characterization and pharmacokinetics in macaques
description
2014 nî lūn-bûn
@nan
2014 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
A new bispecific antibody targ ...... d pharmacokinetics in macaques
@ast
A new bispecific antibody targ ...... d pharmacokinetics in macaques
@en
A new bispecific antibody targ ...... d pharmacokinetics in macaques
@nl
type
label
A new bispecific antibody targ ...... d pharmacokinetics in macaques
@ast
A new bispecific antibody targ ...... d pharmacokinetics in macaques
@en
A new bispecific antibody targ ...... d pharmacokinetics in macaques
@nl
prefLabel
A new bispecific antibody targ ...... d pharmacokinetics in macaques
@ast
A new bispecific antibody targ ...... d pharmacokinetics in macaques
@en
A new bispecific antibody targ ...... d pharmacokinetics in macaques
@nl
P2093
P2860
P1476
A new bispecific antibody targ ...... d pharmacokinetics in macaques
@en
P2093
Dimiter S Dimitrov
Karalyne Crowder
Weizao Chen
Yanping Wang
P2860
P304
P356
10.1016/J.YEXMP.2014.09.007
P577
2014-09-16T00:00:00Z