TDP-43 toxicity proceeds via calcium dysregulation and necrosis in aging Caenorhabditis elegans motor neurons.

TDP-43 toxicity proceeds via calcium dysregulation and necrosis in aging Caenorhabditis elegans motor neurons.

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http://www.wikidata.org/entity/Q34674858
Calcium dysregulation links ALS defective proteins and motor neuron selective vulnerabilityModelling amyotrophic lateral sclerosis: progress and possibilitiesMass spectrometric analysis of accumulated TDP-43 in amyotrophic lateral sclerosis brains.Mitochondria-associated membrane collapse is a common pathomechanism in SIGMAR1- and SOD1-linked ALSCalcium dysregulation, functional calpainopathy, and endoplasmic reticulum stress in sporadic inclusion body myositis.The cleavage pattern of TDP-43 determines its rate of clearance and cytotoxicity.Reactive oxygen species-mediated neurodegeneration is independent of the ryanodine receptor in Caernorhabditis elegans.The Progranulin Cleavage Products, Granulins, Exacerbate TDP-43 Toxicity and Increase TDP-43 Levels.Nuclear localized C9orf72-associated arginine-containing dipeptides exhibit age-dependent toxicity in C. elegans.Neurodegeneration in C. elegans models of ALS requires TIR-1/Sarm1 immune pathway activation in neurons.Insulin Signaling Regulates Oocyte Quality Maintenance with Age via Cathepsin B Activity.
P2860

TDP-43 toxicity proceeds via calcium dysregulation and necrosis in aging Caenorhabditis elegans motor neurons.

Item
http://www.wikidata.org/entity/Q34674858
description
2014 nî lūn-bûn
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2014 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
TDP-43 toxicity proceeds via c ...... abditis elegans motor neurons.
@ast
TDP-43 toxicity proceeds via c ...... abditis elegans motor neurons.
@en
TDP-43 toxicity proceeds via c ...... abditis elegans motor neurons.
@nl
type
label
TDP-43 toxicity proceeds via c ...... abditis elegans motor neurons.
@ast
TDP-43 toxicity proceeds via c ...... abditis elegans motor neurons.
@en
TDP-43 toxicity proceeds via c ...... abditis elegans motor neurons.
@nl
prefLabel
TDP-43 toxicity proceeds via c ...... abditis elegans motor neurons.
@ast
TDP-43 toxicity proceeds via c ...... abditis elegans motor neurons.
@en
TDP-43 toxicity proceeds via c ...... abditis elegans motor neurons.
@nl
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P698
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TDP-43 toxicity proceeds via c ...... abditis elegans motor neurons.
@en
P2093
P2860
P304
P31
P356
10.1523/JNEUROSCI.2495-13.2014
P407
P433
P478
P50
P577
P698
P921
P932